Compound Summary


  Compound Information

药名:

isoorientin

别名:

isoorientin 7-olate; isoorientin(1-); Isoorientin; AIDS-026707; 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-4-chromenone; C01821; NCGC00163566-01; (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-oxido-4-oxo-4H-chromen-6-yl]-D-glucitol; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; 4261-42-1; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]chromone; AIDS026707; CHEBI:58333; CHEBI:17965; (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-6-yl]-D-glucitol; 6C-hexosyl luteolin; Homoorientin; isoorientin anion; isoorientin ; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; Luteolin 6-C-glucoside

分子式:

C21H20O11

Smiles:

c12c(OC(c3c([H])c([H])c(O[H])c(O[H])c3[H])=C([H])C1=O)c([H])c(O[H])c([C@@]4([H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(C([H])([H])O[H])O4)c2O[H]

成分:

HBIN031002

OB_score:

23.295391

CAS_id:

4261-42-1

SymMap_id:

SMIT00054

TCMID_id:

23134

TCMSP_id:

MOL000498;MOL011109

PubChem_id:

114776


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001639 绿豆皮
TCMBANKHE002482 异叶蔓荆
TCMBANKHE002553 荭草花
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE005470 Indigo turalis 青黛 To remove toxic heat, to reduce heat in blood, and to relieve convulsions./1. Inhibiting leukemia7212 and many other other tumors in experimental animals2. Enhancing the fuction of reticuloendothelial system in healthy mice and promoting phagocytosis of macrophage in mice with cancer.3. It may cause abdominal pain, diarrhea or bloody stools.
TCMBANKHE003967 Radix Platycodi 桔梗 To relieve cought, to soothe sore throat, and to promote expectoration and discharge of pus./Cough with profuse phlegm, swelling pain in throat, pulmonary welling abscess with hacking of pus and blood, fullness in chest and rib-side pain, dysentery, dribbling urinary block.
TCMBANKHE004160 Semen Cassiae;Semen Sene 决明子 To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia.
TCMBANKHE004586 香茅 Common cold with headache, diarrhea, wind-cold impediment pain, cold pain in stomach duct and abdomen, knocks and falls.
TCMBANKHE007206 Lignum Santaii Albi 檀香 To promote the flow of qi in the heart, to warm the spleen and stomach, to increse appetite, and to relieve pain./Pain in chest and abdomen, cold stomachache, vomiting of water due to congealing cold qi stagnation, coronary heart disease with pattern of qi stagnation and blood stasis.
TCMBANKHE007156 Herba Patriniae 败酱草 1. To eliminate heat and toxic material, relieve abscess and promote pus drainage. 2. To remove blood stasis and alleviate pain/1. Two active components, patrinene and isopatrinene, possess sedative effect. 2. To promote regeneration of hepatic cells and portal circulation, protect hepatic cells from degernation and improve hepatic function.
TCMBANKHE007523 Folium Polygoni Tinctorii 蓼大青叶 To remove toxic heat, and to cause subsidence of eruptions by reducing heat in blood./Treatment of fever and eruptions in epidemic diseases, cough and asthma due to heat in the lung, inflammation of the throat, mnmps, erysipelas, carbuncle.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE005736 Herba Commelie 鸭跖草 1. Clear away heat and toxic materials. 2. Clear away heat and promote diuresis. /Common cold, wind-heat common cold, influenza, noninfectious fever, ardent fever incessant, ascites, edema, hordeolum, swelling pain in throat, scant urine with edema, heat strangury with inhibited pain, swollen welling abscess and toxin of clove.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE006352 Abrus Precatorius L. 相思子 Vomiting, welling abscess, parotitis, scab and lichen, wind-damp bone pain.
TCMBANKHE007224 Tripterospermum taiwanense 台湾双蝴蝶 To clear heat and resolve toxin, suppress cough./Jaundice, wind-heat cough.
TCMBANKHE009034 Fructus Polygoni Orientalis 水红花子 To reduce masses by dissipating blood stasis, and to relieve pain by removing stagnancy of food./Treatment of mass in the abdomen, goitre with pain, epigastric pain and distension due to indigestion.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE009129 Flos Trollii chinensis 金莲花 For clearing heat and removing toxic substances/Common cold with fever, swelling pain in throat, mouth sore, gum swelling and pain, gum hemorrhage, red eyes with gall, swelling toxin of clove sore, acute periostitis, acute lymphangitis.
TCMBANKHE007269 Fructus Viticis 蔓荆子 To dispel wind-heat from the head and eyes./Externally contracted wind-heat, dizziness and headache, migraine, gum swelling and pain, red eyes with gall, delacrimation, wind-damp impediment pain, hypertonicity of limbs.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE008279 山楂叶 Hypertension, lacquer sore, enduring sores.
TCMBANKHE006959/YNS-135/YEM-14 Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L. 决明子;草决明|决明 决明根|草决明 云南药材标准:第三册|云南民族药物志:第一卷 安神补脑,清肝明目,理气止痛。主治失眠多梦,入睡易惊,腹内痉挛剧痛,腹部包块,黄疸,疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic. 傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族
TCMBANKHE004801/YEM-339 Herba Verbae|Verbena officinalis L. 马鞭草 马鞭草 云南民族药物志:第二卷 To promote the flow of blood and to relieve blood stasis, to stop malarial attacks, to counteract toxicity, and to cause diuresis./Malaria, amenorrhea and dysmenorrhea, throat impediment, edema, heat strangury, diphtheria, bilharziosis, dysentery, concretion conglomeration accumulation and gathering. 白族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/纳西族/普米族/佤族/彝族/藏族/壮族
TCMBANKHE005494/YEM-445 Fructus Hordei Germitus|Hordeum vulgare L. 麦芽|大麦 大麦 云南民族药物志:第三卷 To invigo rate the function of the spleen, to regulate the function of the stomach, and to promote the flow of milk./Food accumulation, abdominal distention and diarrhea, nausea and vomiting, inappetence, galactostasis, distending pain in breast. 佤族/彝族
TCMBANKHE006849/YEM-65 Gentiana rhodantha|Gentiana rhodantha Franch.ex Hemsl. 红花龙胆 红花龙胆 云南民族药物志:第一卷 To clear heat and disinhibit damp, cool blood and resolve toxin./Cough and asthma due to lung heat, consumption cough with phlegm and blood, jaundice, dysentery, bloody stool, inhibited urination, postpartum fever, infant fright wind, gan accumulation, toxin swelling of sores, burns and scalds, snake bite. 哈尼族/傈僳族/藏族
TCMBANKHE007022/YEM-929/XU-706 Spica Prunellae|Prunella vulgaris L.|Prunella vulgaris 夏枯草 夏枯草 云南民族药物志:第五卷|云南红河屏边县 To quench fire of the liver and counteract inflammation of the eye, and to reduce modulation and induce subsidence of swelling./Red eyes with gall, eyeball night pain, headache and dizziness, scrofula, goiter and tuberculosis, mammary welling abscess, thyroid enlargement, scrofula, hyperplasia of mammary glands, hypertension. 阿昌族/白族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/水族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000290 NQO1 DHQU; DIA4; DTD; NMOR1; NMORI; QR1 NAD(P)H quinone dehydrogenase 1
TCMBANKGE001126 NFE2L2 HEBP1; IMDDHH; NRF2; Nrf-2 nuclear factor, erythroid 2 like 2
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1