Compound Summary


  Compound Information

药名:

Isoliensinine

别名:

7-Isoquinolinol, 1,2,3,4-tetrahydro-1-((4-hydroxy-3-((1,2,3,4-tetrahydro-6-methoxy-1-((4-methoxyphenyl)methyl)-2-methyl-7-isoquinolinyl)oxy)phenyl)methyl)-6-methoxy-2-methyl-, (R-(R*,R*))-; 1-{[4-hydroxy-3-({6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl}oxy)phenyl]methyl}-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol; (1R)-1-[4-hydroxy-3-[[(1R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]benzyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; Isoliensinine; Isoliensinin; 6817-41-0; (1R)-1-[[4-hydroxy-3-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenyl]methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-hydroxy-3-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]phenyl]methyl]-6-methoxy-2-methyl-, (1R)-; AIDS-226951; AIDS226951

分子式:

C39H45NO6

Smiles:

c1(OC([H])([H])[H])c([H])c(C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(C([H])([H])[H])C([H])([H])c3c([H])c([H])c(OC([H])([H])[H])c([H])c3[H])c2c([H])c1Oc4c(O[H])c([H])c([H])c(C([H])([H])[C@] 5([H])c(c([H])c(O[H])c(OC([H])([H])[H])c6[H])c6C([H])([H])C([H])([H])N5C([H])([H])[H])c4[H]

成分:

HBIN030869

OB_score:

2.435712

CAS_id:

6817-41-0

SymMap_id:

SMIT00754

TCMID_id:

11488

TCMSP_id:

MOL009168

PubChem_id:

5274591


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000350 Receptaculum Nelumbinis 莲房 To remove blood stasis and arrest bleeding./Treatment of abnormal uterine bleeding, hematurial hemorrhoidal bleeding, postpartum blood stasis, lochiorrhea.
TCMBANKHE002237 Stamen Nelumbinis 莲须 To astringe the kindey and arrest spontaneous emission./Treatment of seminal emission, spermatorrhea, excessive leukorrhea, frequent urination.
TCMBANKHE002277 荷花
TCMBANKHE002301 莲衣
TCMBANKHE004755 Semen Impatientis 急性子 To remove stagnation of qi, eliminate blood stasis, and soften hard masses./Concretion and conglomeration, lump glomus, amenorrhea, dysphagia-occlusion.
TCMBANKHE003720 herba centellae 积雪草 To remove heat and damp, to counteract toxicity, and to cause subsidence of swelling./Sand qi abdominal pain, summerheat-heat diarrhea, dysentery, damp-heat jaundice, sand strangury, blood strangury, blood ejection, spontaneous external bleeding, red eyes, swollen throat, wind papules, scab and lichen, swelling toxin of clove welling abscess, knocks and falls, hypertension.
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE004086 Plumula Nelumbinis 莲子心 To remove heat from the heart and calm the nerves, to restore the coordination between the heart and the kidney, to check emission, and to arrest bleeding./Heat entering pericardium, clouded spirit with delirious speech, non-interaction of heart and kidney, insomnia and emission, blood ejection due to blood heat, hypertension.
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE006761 nodus nelumbinis rhizomatis 藕节 To arrest bleeding and remove blood stasis./Treament of hematemesis, hemoptysis, hematuria, abnormal uterine bleeding.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE005111/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 荷叶蒂|莲 云南民族药物志:第一卷 To clear summerheat and eliminate damp, dispel stasis and stanch bleeding, quiet fetus./Summerheat-damp diarrhea, blood dysentery, flooding and spotting, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE008259/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 荷梗|莲 云南民族药物志:第一卷 To dispel summerheat, rectify qi and transform damp./Summerheat-damp and oppression in chest, diarrhea, dysentery, strangury, Vaginal discharge. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE006652/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 莲子|莲 云南民族药物志:第一卷 To supplement spleen and check diarrhea, boost kidney and secure essence, nourish heart and quiet spirit./Chronic diarrhea, inappetence, emission, restlessness, fright palpitation, insomnia, flooding and spotting, excessive leukorrhea. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005257/YEM-104 Folium Nelumbinis|Nelumbo nucifera Gaertn. 荷叶|莲 云南民族药物志:第一卷 To relieve summer-heat, to invigorate the spleen function of the spleen and arrest bleeding by reducing heat in blood./Summerheat-heat vexation and thirst, summerheat-damp diarrhea, spleen vacuity diarrhea, blood heat, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE007683/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 藕|莲 云南民族药物志:第一卷 To clear heat and engender liquid, cool blood, stanch bleeding and dissipate stasis./Febrile diseases with vexation and thirst, blood ejection, spontaneous external bleeding, precipitate blood. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE003733/YEM-396 Melia azedarach 莲花|棟 苦棟皮 云南民族药物志:第二卷 To clear heat and dispel damp, kill worms and relieve itch./Prickly heat. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/普米族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000298 SOD1 ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer superoxide dismutase 1