Compound Summary


  Compound Information

药名:

2'-O-methylisoliquiritigenin

别名:

(E)-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; C15531; 2'-o-methyl isoliquiritigenin; 2'-O-Methyl isoliquiritigenin; (E)-1-(4-hydroxy-2-methoxy-phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

分子式:

C16H14O4

Smiles:

c1(O[H])c([H])c([H])c(C(=O)\C([H])=C([H])\c2c([H])c([H])c(O[H])c([H])c2[H])c(OC([H])([H])[H])c1[H]

成分:

HBIN006254

OB_score:

75.856011

CAS_id:

51828-10-5

SymMap_id:

SMIT05104;SMIT16651

TCMID_id:

14524

TCMSP_id:

MOL002955

PubChem_id:

25201046


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004344 南鹤虱 Ascariasis, oxyuria disease, taeniasis, ancylostomiasis, abdominal pain due to worm accumulation, child gan accumulation, pudendal itch.
TCMBANKHE001170 猕猴桃根
TCMBANKHE002237 Stamen Nelumbinis 莲须 To astringe the kindey and arrest spontaneous emission./Treatment of seminal emission, spermatorrhea, excessive leukorrhea, frequent urination.
TCMBANKHE005727 南鹤虱
TCMBANKHE005732 Dalbergia odorifera 降真香 To quicken blood and dissipate stasis, stanch bleeding and settle pain, downbear qi , break foul./Chest and rib-side pain, knocks and falls, bleeding due to external injury, bleeding due to external injury.
TCMBANKHE004862 Lignum Dalbergiae odoriferae Rosewood 降香 To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits.
TCMBANKHE005039 Semen Sterculiae Lychnophorae 胖大海 To remove heat from the lung, to cure sore throat, to counteract toxicity, and to relax the bowels./Treament of hoarseness of voice, dry cough, and sore, dry throat due to heat in the lung, constipation with headache and blood-shot eyes.
TCMBANKHE008054 Cymbopogon goeringii 野香茅 To relieve cough and calm asthma, dispel wind and eliminate damp, free channels and relieve pain, check diarrhea./Acute bronchitis, chronic bronchitis, bronchitis, rheumatic arthritis, headache, knocks and falls, diarrhea, qi pain in heart and stomach, abdominal pain, water diarrhea.
TCMBANKHE005688 Rhizoma Acori Talarinowii 石菖蒲 To eliminate damp and phlegm, to improve appetite, and to restore consciousness and benefit the mentality./Febrile diseases clouded spirit, phlegm reversal, amnesia, tinnitus, deafness, distending pain in stomach duct and abdomen, food-denying dysentery, wind-damp impediment pain, knocks and falls, scab and lichen with welling abscess and flat abscess.
TCMBANKHE006927 Asarum europaeum 欧细辛
TCMBANKHE007004 Semen Myristicae 肉豆蔻 To warm the spleen and stomach and promote the flow of qi , to arrest diarrhea as an astringent./Spleen-stomach vacuity cold, incessant chronic diarrhea, distending pain in stomach duct, reduced food intake with vomiting.
TCMBANKHE005594/YEM-148 Acorus calamus|Acorus calamus L. 白鲳;白菖|菖蒲 水菖蒲 云南民族药物志:第一卷 To transform phlegm and open orifices, dispel damp and fortify stomach, kill worms and relieve itch./Stupor due to phlegm reversal, wind stroke, epilepsy, fright palpitation and amnesia, tinnitus and deafness, food accumulation abdominal pain, diarrhea and dysentery, wind-damp pain, eczema, scab sore. 阿昌族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/怒族/普米族/佤族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003260 HBA1 ECYT7; HBA-T3; HBH; METHBA hemoglobin subunit alpha 1
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1