Compound Summary

  Compound Information

TCMBANKIN049920

药名:	alpha-Lipoic acid
别名:	α-lipoicacid; 5-[1,2]-dithiolan-3-yl-pentanoic acid
分子式:	C8H14O2S2
Smiles:	C1([H])([H])C([H])([H])[C@]([H])(SS1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H]
成分:	HBIN015585
TCMID_id:	23187;12894
PubChem_id:	864

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004864	Porphyra tenera	紫菜			To transform phlegm and soften hardness, clear heat and disinhibit urine./Goiter and tuberculosis, beriberi, edema, strangury, swelling pain in throat, cough, diarrhea.
TCMBANKHE005024	Liriodendron tulipifera	北美鹅掌楸			To dispel wind and eliminate damp, dissipate cold and relieve cough./Wind-damp impediment pain, wind-cold cough.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000067	NCF1	NCF1A; NOXO2; SH3PXD1A; p47phox	neutrophil cytosolic factor 1
TCMBANKGE000139	POR	CPR; CYPOR; P450R	cytochrome p450 oxidoreductase
TCMBANKGE000261	INS	IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10; PNDM4	insulin
TCMBANKGE000274	CCL2	GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF	C-C motif chemokine ligand 2
TCMBANKGE000298	SOD1	ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer	superoxide dismutase 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000562	IL18	IGIF; IL-18; IL-1g; IL1F4	interleukin 18
TCMBANKGE000614	LTBP1	-	latent transforming growth factor beta binding protein 1
TCMBANKGE000699	CYBA	p22-PHOX	cytochrome b-245 alpha chain
TCMBANKGE000758	HSF1	HSTF1	heat shock transcription factor 1
TCMBANKGE000787	VCAM1	CD106; INCAM-100	vascular cell adhesion molecule 1
TCMBANKGE000872	IGF1R	CD221; IGFIR; IGFR; JTK13	insulin like growth factor 1 receptor
TCMBANKGE001042	PTPN1	PTP1B	protein tyrosine phosphatase non-receptor type 1
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001076	SOD2	GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD	superoxide dismutase 2
TCMBANKGE001077	HSPA5	BIP; GRP78; HEL-S-89n; MIF2	heat shock protein family A (Hsp70) member 5
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001135	SREBF1	SREBP1; bHLHd1	sterol regulatory element binding transcription factor 1
TCMBANKGE001149	PPARGC1A	LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1	PPARG coactivator 1 alpha
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001167	CDC37	P50CDC37	cell division cycle 37, HSP90 cochaperone
TCMBANKGE001176	CAT	-	catalase
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE005460	XPR1	IBGC6; SLC53A1; SYG1; X3	xenotropic and polytropic retrovirus receptor 1
TCMBANKGE007230	FXN	CyaY; FA; FARR; FRDA; X25	frataxin
TCMBANKGE008566	PNP	NP; PRO1837; PUNP	purine nucleoside phosphorylase
TCMBANKGE010804	PRKAG2	AAKG; AAKG2; CMH6; H91620p; WPWS	protein kinase AMP-activated non-catalytic subunit gamma 2
TCMBANKGE013026	HSPD1	CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13	heat shock protein family D (Hsp60) member 1