Compound Summary
Compound Information
药名: | 7-hydroxymitragynine |
分子式: | C23H30N2O5 |
Smiles: | CCC1CN2CCC3(C(=NC4=C3C(=CC=C4)OC)C2CC1C(=COC)C(=O)OC)O |
成分: | HBIN013289 |
TCMID_id: | 10527 |
PubChem_id: | 139024851 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000015 | ADORA2A | A2aR; ADORA2; RDC8 | adenosine A2a receptor |
| TCMBANKGE000061 | OXTR | OT-R | oxytocin receptor |
| TCMBANKGE000135 | CXCR4 | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS | C-X-C motif chemokine receptor 4 |
| TCMBANKGE000154 | CCR2 | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | C-C motif chemokine receptor 2 |
| TCMBANKGE000219 | CCR5 | CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22 | C-C motif chemokine receptor 5 |
| TCMBANKGE000386 | GPR83 | GIR; GPR72 | G protein-coupled receptor 83 |
| TCMBANKGE000408 | CCR3 | C C CKR3; CC-CKR-3; CD193; CKR 3; CKR3; CMKBR3 | C-C motif chemokine receptor 3 |
| TCMBANKGE000409 | CCR4 | CC-CKR-4; CD194; CKR4; CMKBR4; ChemR13; HGCN:14099; K5-5 | C-C motif chemokine receptor 4 |
| TCMBANKGE000434 | PTGER2 | EP2 | prostaglandin E receptor 2 |
| TCMBANKGE000514 | CNR1 | CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR | cannabinoid receptor 1 |
| TCMBANKGE000522 | AGTR1 | AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R | angiotensin II receptor type 1 |
| TCMBANKGE000536 | EDNRB | ABCDS; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A | endothelin receptor type B |
| TCMBANKGE000633 | ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | adrenoceptor beta 2 |
| TCMBANKGE000705 | GPR84 | EX33; GPCR4 | G protein-coupled receptor 84 |
| TCMBANKGE000753 | CNR2 | CB-2; CB2; CX5 | cannabinoid receptor 2 |
| TCMBANKGE000801 | HTR1A | 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD | 5-hydroxytryptamine receptor 1A |
| TCMBANKGE000861 | PTGER4 | EP4; EP4R | prostaglandin E receptor 4 |
| TCMBANKGE000869 | DRD2 | D2DR; D2R | dopamine receptor D2 |
| TCMBANKGE001194 | ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | adrenoceptor alpha 2A |
| TCMBANKGE001195 | RXFP3 | GPCR135; RLN3R1; RXFPR3; SALPR | relaxin family peptide receptor 3 |
| TCMBANKGE001417 | HTR1E | 5-HT1E | 5-hydroxytryptamine receptor 1E |
| TCMBANKGE001469 | GPR78 | - | G protein-coupled receptor 78 |
| TCMBANKGE001506 | ADRA1B | ADRA1; ALPHA1BAR | adrenoceptor alpha 1B |
| TCMBANKGE001830 | LSP1 | WP34; pp52 | lymphocyte specific protein 1 |
| TCMBANKGE001861 | BDKRB1 | B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1 | bradykinin receptor B1 |
| TCMBANKGE001943 | ADRA1D | ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 | adrenoceptor alpha 1D |
| TCMBANKGE002118 | GPR176 | HB-954 | G protein-coupled receptor 176 |
| TCMBANKGE002262 | PROKR1 | GPR73; GPR73a; PK-R1; PKR1; ZAQ | prokineticin receptor 1 |
| TCMBANKGE002264 | ACKR3 | CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1 | atypical chemokine receptor 3 |
| TCMBANKGE002321 | SSTR1 | SRIF-2; SS-1-R; SS1-R; SS1R | somatostatin receptor 1 |
| TCMBANKGE002362 | GPR22 | - | G protein-coupled receptor 22 |
| TCMBANKGE002391 | LPAR3 | EDG7; Edg-7; GPCR; HOFNH30; LP-A3; LPA3; RP4-678I3 | lysophosphatidic acid receptor 3 |
| TCMBANKGE002393 | GRPR | BB2; BB2R | gastrin releasing peptide receptor |
| TCMBANKGE002550 | NPSR1 | ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1 | neuropeptide S receptor 1 |
| TCMBANKGE002560 | NTSR1 | NTR | neurotensin receptor 1 |
| TCMBANKGE002563 | GPR37 | EDNRBL; PAELR; hET(B)R-LP | G protein-coupled receptor 37 |
| TCMBANKGE002564 | GPR65 | TDAG8; hTDAG8 | G protein-coupled receptor 65 |
| TCMBANKGE002688 | HTR1F | 5-HT-1F; 5-HT1F; 5HT6; HTR1EL; MR77 | 5-hydroxytryptamine receptor 1F |
| TCMBANKGE002734 | TAAR2 | GPR58; taR-2 | trace amine associated receptor 2 |
| TCMBANKGE003053 | HTR2B | 5-HT(2B); 5-HT-2B; 5-HT2B | 5-hydroxytryptamine receptor 2B |
| TCMBANKGE003079 | CCKBR | CCK-B; CCK2R; GASR | cholecystokinin B receptor |
| TCMBANKGE003267 | LTB4R2 | BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9 | leukotriene B4 receptor 2 |
| TCMBANKGE003313 | SSTR5 | SS-5-R | somatostatin receptor 5 |
| TCMBANKGE003502 | GNRHR | GNRHR1; GRHR; HH7; LHRHR; LRHR | gonadotropin releasing hormone receptor |
| TCMBANKGE003584 | HCRTR1 | OX1R | hypocretin receptor 1 |
| TCMBANKGE003646 | HRH2 | H2R; HH2R | histamine receptor H2 |
| TCMBANKGE003680 | ADORA2B | ADORA2 | adenosine A2b receptor |
| TCMBANKGE003718 | NTSR2 | NTR2 | neurotensin receptor 2 |
| TCMBANKGE003874 | CXCR6 | BONZO; CD186; STRL33; TYMSTR | C-X-C motif chemokine receptor 6 |
| TCMBANKGE003910 | NPY4R2 | CH17-360D5.1; NPY4-R; NPY4R; PP1; PPYR1 | neuropeptide Y receptor Y4-2 |
| TCMBANKGE003934 | HTR2C | 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C | 5-hydroxytryptamine receptor 2C |
| TCMBANKGE003975 | GPR119 | GPCR2 | G protein-coupled receptor 119 |
| TCMBANKGE004030 | AVPR1A | AVPR V1a; AVPR1; V1aR | arginine vasopressin receptor 1A |
| TCMBANKGE004055 | SSTR4 | SS-4-R; SS4-R; SS4R | somatostatin receptor 4 |
| TCMBANKGE004143 | KISS1R | AXOR12; CPPB1; GPR54; HH8; HOT7T175; KISS-1R | KISS1 receptor |
| TCMBANKGE004308 | GPR12 | GPCR12; GPCR21; PPP1R84 | G protein-coupled receptor 12 |
| TCMBANKGE004324 | RGR | RP44 | retinal G protein coupled receptor |
| TCMBANKGE004376 | TAAR1 | TA1; TAR1; TRAR1 | trace amine associated receptor 1 |
| TCMBANKGE004445 | OPN5 | GPR136; GRP136; PGR12; TMEM13 | opsin 5 |
| TCMBANKGE004548 | CCR9 | CC-CKR-9; CDw199; GPR-9-6; GPR28 | C-C motif chemokine receptor 9 |
| TCMBANKGE004757 | HTR6 | 5-HT6; 5-HT6R | 5-hydroxytryptamine receptor 6 |
| TCMBANKGE004828 | HRH3 | GPCR97; HH3R | histamine receptor H3 |
| TCMBANKGE004913 | TBXA2R | BDPLT13; TXA2-R | thromboxane A2 receptor |
| TCMBANKGE005056 | NPBWR2 | GPR8 | neuropeptides B and W receptor 2 |
| TCMBANKGE005381 | GPR52 | - | G protein-coupled receptor 52 |
| TCMBANKGE005406 | CCR1 | CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1 | C-C motif chemokine receptor 1 |
| TCMBANKGE005598 | HTR4 | 5-HT4; 5-HT4R | 5-hydroxytryptamine receptor 4 |
| TCMBANKGE005603 | PTGFR | FP | prostaglandin F receptor |
| TCMBANKGE005674 | GPR3 | ACCA | G protein-coupled receptor 3 |
| TCMBANKGE005777 | AGTR2 | AT2; ATGR2; MRX88 | angiotensin II receptor type 2 |
| TCMBANKGE005805 | MC1R | CMM5; MSH-R; SHEP2 | melanocortin 1 receptor |
| TCMBANKGE005975 | ADORA1 | RDC7 | adenosine A1 receptor |
| TCMBANKGE006055 | MCHR1 | GPR24; MCH-1R; MCH1R; SLC-1; SLC1 | melanin concentrating hormone receptor 1 |
| TCMBANKGE006079 | NMUR2 | FM-4; FM4; NMU-R2; NMU2R; TGR-1; TGR1 | neuromedin U receptor 2 |
| TCMBANKGE006096 | GALR3 | - | galanin receptor 3 |
| TCMBANKGE006136 | OPN1SW | BCP; BOP; CBT | opsin 1, short wave sensitive |
| TCMBANKGE006164 | GPR21 | - | G protein-coupled receptor 21 |
| TCMBANKGE006224 | PTGIR | IP; PRIPR | prostaglandin I2 receptor |
| TCMBANKGE006459 | GPR135 | HUMNPIIY20 | G protein-coupled receptor 135 |
| TCMBANKGE006486 | FFAR4 | BMIQ10; GPR120; GPR129; GT01; O3FAR1; PGR4 | free fatty acid receptor 4 |
| TCMBANKGE006657 | MC2R | ACTHR | melanocortin 2 receptor |
| TCMBANKGE006755 | GPR27 | SREB1 | G protein-coupled receptor 27 |
| TCMBANKGE006851 | MLNR | GPR38; MTLR1 | motilin receptor |
| TCMBANKGE006869 | PTGER3 | EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; PGE2-R; lnc003875 | prostaglandin E receptor 3 |
| TCMBANKGE006915 | MC5R | MC2 | melanocortin 5 receptor |
| TCMBANKGE007058 | GPR37L1 | ET(B)R-LP-2; ETBR-LP-2; ETBRLP2 | G protein-coupled receptor 37 like 1 |
| TCMBANKGE007107 | NPFFR2 | GPR74; HLWAR77; NPFF2; NPGPR | neuropeptide FF receptor 2 |
| TCMBANKGE007136 | GPR45 | PSP24; PSP24(ALPHA); PSP24A | G protein-coupled receptor 45 |
| TCMBANKGE007314 | GPR101 | GPCR6; PAGH2; PITA2 | G protein-coupled receptor 101 |
| TCMBANKGE007496 | GPR161 | RE2 | G protein-coupled receptor 161 |
| TCMBANKGE007635 | NMUR1 | (FM-3); FM-3; FM3; GPC-R; GPR66; NMU1R | neuromedin U receptor 1 |
| TCMBANKGE007713 | LPAR1 | EDG2; GPR26; Gpcr26; LPA1; Mrec1.3; VZG1; edg-2; rec.1.3; vzg-1 | lysophosphatidic acid receptor 1 |
| TCMBANKGE007896 | AVPR2 | ADHR; DI1; DIR; DIR3; NDI; V2R | arginine vasopressin receptor 2 |
| TCMBANKGE007952 | GPR173 | SREB3 | G protein-coupled receptor 173 |
| TCMBANKGE007963 | GPR26 | - | G protein-coupled receptor 26 |
| TCMBANKGE008011 | HTR2A | 5-HT2A; HTR2 | 5-hydroxytryptamine receptor 2A |
| TCMBANKGE008056 | ADRA2C | ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR | adrenoceptor alpha 2C |
| TCMBANKGE008255 | GPR6 | - | G protein-coupled receptor 6 |
| TCMBANKGE008272 | GPR62 | GPCR8; KPG_005 | G protein-coupled receptor 62 |
| TCMBANKGE008311 | QRFPR | AQ27; GPR103; SP9155 | pyroglutamylated RFamide peptide receptor |
| TCMBANKGE008550 | RRH | - | retinal pigment epithelium-derived rhodopsin homolog |
| TCMBANKGE008588 | GPR88 | COCPMR; STRG | G protein-coupled receptor 88 |
| TCMBANKGE008702 | OPRM1 | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM | opioid receptor mu 1 |
| TCMBANKGE008743 | OPRK1 | K-OR-1; KOP; KOR; KOR-1; KOR1; OPRK | opioid receptor kappa 1 |
| TCMBANKGE008845 | GALR1 | GALNR; GALNR1 | galanin receptor 1 |
| TCMBANKGE009032 | TAAR6 | TA4; TAR4; TAR6; TRAR4; taR-4; taR-6 | trace amine associated receptor 6 |
| TCMBANKGE009036 | GPR19 | - | G protein-coupled receptor 19 |
| TCMBANKGE009228 | GPR151 | GALR4; GALRL; GPCR; GPCR-2037; PGR7 | G protein-coupled receptor 151 |
| TCMBANKGE009253 | GPR139 | GPRg1; PGR3 | G protein-coupled receptor 139 |
| TCMBANKGE009319 | GPR61 | BALGR; GPCR3 | G protein-coupled receptor 61 |
| TCMBANKGE009476 | NPY5R | NPY5-R; NPYR5; NPYY5-R | neuropeptide Y receptor Y5 |
| TCMBANKGE009615 | PTGER1 | EP1 | prostaglandin E receptor 1 |
| TCMBANKGE009707 | GALR2 | GAL2-R; GALNR2; GALR-2 | galanin receptor 2 |
| TCMBANKGE009836 | AVPR1B | AVPR3; V1bR | arginine vasopressin receptor 1B |
| TCMBANKGE010343 | TRHR | CHNG7; TRH-R | thyrotropin releasing hormone receptor |
| TCMBANKGE010398 | MCHR2 | GPR145; GPRv17; MCH-2R; MCH-R2; MCH2; MCH2R; MCHR-2; SLT | melanin concentrating hormone receptor 2 |
| TCMBANKGE010467 | MC4R | BMIQ20 | melanocortin 4 receptor |
| TCMBANKGE010579 | NPY1R | NPY1-R; NPYR | neuropeptide Y receptor Y1 |
| TCMBANKGE010680 | RXFP4 | GPCR142; GPR100; RLN3R2; RXFPR4 | relaxin family peptide/INSL5 receptor 4 |
| TCMBANKGE010800 | GPR85 | SREB; SREB2 | G protein-coupled receptor 85 |
| TCMBANKGE010854 | TAAR8 | GPR102; TA5; TAR5; TRAR5; TaR-5; TaR-8 | trace amine associated receptor 8 |
| TCMBANKGE010907 | PROKR2 | GPR73L1; GPR73b; GPRg2; HH3; KAL3; PKR2; dJ680N4.3 | prokineticin receptor 2 |
| TCMBANKGE010943 | BRS3 | BB3; BB3R; BBR3 | bombesin receptor subtype 3 |
| TCMBANKGE011045 | TMIGD3 | AD026 | transmembrane and immunoglobulin domain containing 3 |
| TCMBANKGE011156 | PRLHR | GPR10; GR3; PrRPR | prolactin releasing hormone receptor |
| TCMBANKGE011260 | GPR63 | PSP24(beta); PSP24B | G protein-coupled receptor 63 |
| TCMBANKGE011385 | APLNR | AGTRL1; APJ; APJR; HG11 | apelin receptor |
| TCMBANKGE011551 | GPR39 | - | G protein-coupled receptor 39 |
| TCMBANKGE011700 | GPR142 | GPRg1b; PGR2 | G protein-coupled receptor 142 |
| TCMBANKGE011775 | OPN4 | MOP | opsin 4 |
| TCMBANKGE011803 | HTR7 | 5-HT7 | 5-hydroxytryptamine receptor 7 |
| TCMBANKGE011860 | NPBWR1 | GPR7 | neuropeptides B and W receptor 1 |
| TCMBANKGE012197 | PTGDR | AS1; ASRT1; DP; DP1; PTGDR1 | prostaglandin D2 receptor |
| TCMBANKGE012345 | DRD3 | D3DR; ETM1; FET1 | dopamine receptor D3 |
| TCMBANKGE012350 | GPR148 | BTR; PGR6 | G protein-coupled receptor 148 |
| TCMBANKGE012438 | NPY2R | NPY2-R | neuropeptide Y receptor Y2 |
| TCMBANKGE012594 | RHO | CSNBAD1; OPN2; RP4 | rhodopsin |
| TCMBANKGE012889 | OPRL1 | KOR-3; KOR3; NOCIR; NOP; NOPr; OOR; OPRL; ORL1 | opioid related nociceptin receptor 1 |
| TCMBANKGE012982 | HTR5A | 5-HT5A | 5-hydroxytryptamine receptor 5A |
| TCMBANKGE013226 | DRD4 | D4DR | dopamine receptor D4 |
| TCMBANKGE013375 | LTB4R | BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7 | leukotriene B4 receptor |
| TCMBANKGE013468 | NMBR | BB1; BB1R; NMB-R | neuromedin B receptor |
| TCMBANKGE013687 | NPFFR1 | GPR147; NPFF1; NPFF1R1; OT7T022 | neuropeptide FF receptor 1 |
| TCMBANKGE013697 | TAAR5 | PNR | trace amine associated receptor 5 |
| TCMBANKGE013729 | OPN1LW | CBBM; CBP; COD5; RCP; ROP | opsin 1, long wave sensitive |
| TCMBANKGE013826 | DRD5 | DBDR; DRD1B; DRD1L2 | dopamine receptor D5 |
| TCMBANKGE013860 | EDNRA | ET-A; ETA; ETA-R; ETAR; ETRA; MFDA; hET-AR | endothelin receptor type A |
| TCMBANKGE013874 | GHSR | GHDP | growth hormone secretagogue receptor |
| TCMBANKGE014009 | CCKAR | CCK-A; CCK1-R; CCK1R; CCKRA | cholecystokinin A receptor |
| TCMBANKGE014106 | LPAR2 | EDG-4; EDG4; LPA-2; LPA2 | lysophosphatidic acid receptor 2 |
| TCMBANKGE014188 | HRH4 | AXOR35; BG26; GPCR105; GPRv53; H4; H4R; HH4R | histamine receptor H4 |
| TCMBANKGE014221 | OPN3 | ECPN; PPP1R116 | opsin 3 |
| TCMBANKGE014319 | GPR150 | PGR11 | G protein-coupled receptor 150 |
| TCMBANKGE014423 | ADRA1A | ADRA1C; ADRA1L1; ALPHA1AAR | adrenoceptor alpha 1A |
| TCMBANKGE014625 | OPRD1 | DOP; DOR; DOR1; OPRD | opioid receptor delta 1 |
| TCMBANKGE014693 | ADRB3 | BETA3AR | adrenoceptor beta 3 |
| TCMBANKGE014724 | MC3R | BMIQ9; MC3; MC3-R; OB20; OQTL | melanocortin 3 receptor |
| TCMBANKGE014756 | HCRTR2 | OX2R | hypocretin receptor 2 |
| TCMBANKGE014790 | ADRB1 | ADRB1R; B1AR; BETA1AR; FNSS2; RHR | adrenoceptor beta 1 |
| TCMBANKGE014812 | SSTR2 | - | somatostatin receptor 2 |
| TCMBANKGE014869 | HTR1B | 5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12 | 5-hydroxytryptamine receptor 1B |
| TCMBANKGE014873 | OPN1MW2 | GOP | opsin 1, medium wave sensitive 2 |
| TCMBANKGE015084 | UTS2R | GPR14; UR-2-R; UTR; UTR2 | urotensin 2 receptor |
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Dai SX Lab