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Compound Summary

Compound Information

TCMBANKIN050326

药名:	saponin
别名:	Saponin
分子式:	C45H73NO15
Smiles:	[C@]1([H])(O[H])[C@@]([H])(C([H])([H])O[H])O[C@@]([H])(O[C@]2([H])[C@@]([H])(O[C@@]3([H])O[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]3([H])O[H])[C@]([H])(O[C@]4([H])C([H])([H])C(=C( [H])C([H])([H])[C@]5([H])[C@]6([H])C([H])([H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])([C@]([H])(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C7([H])[H])N78)[C@]8([H])C9( [H])[H])[C@]59[H])[C@]6(C([H])([H])[H])C([H])([H])C4([H])[H])O[C@]([H])(C([H])([H])O[H])[C@]2([H])O[H])[C@]([H])(O[H])[C@@]1([H])O[H]
成分:	HBIN043106
SymMap_id:	SMIT01668;SMIT11242
TCMID_id:	23110
TCMSP_id:	MOL010173

化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000271		木瓜核
TCMBANKHE000459	Flos Albiziae	合欢花			Treatment of anxiety, depression and insomnia./Treatment of anxiety, depression and insomnia.
TCMBANKHE002730		橘络
TCMBANKHE002863		木瓜枝
TCMBANKHE003257		木瓜根
TCMBANKHE004803	Radix Rubiae	茜草			To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge./1. Hemostatic. 2. Bacteriostatic in vitro. 3. Antitussive and expectorant.
TCMBANKHE008901	Radix Pseudostellariae	太子参			To replenish qi and invigorate the spleen function, and topromote fluid secretion and moisten the lung./Treatment of hypofunction of the spleen with lassitude and anorexia, debility and deficiency of qi and yin marked by spontaneous sweating and thirst during convalescence dry cough due to dryness of the lung.
TCMBANKHE006755	Herba Hyperici japonici	田基黄;地耳草			1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE007023		猫眼草			Phlegm-rheum cough asthma, edema, scrofula, scab and lichen, innominate toxin swelling.
TCMBANKHE006664/YNS-181/XU-60/XU-236	Fructus Arctii lappae\|Arctium lappa L.\|Arctium lappa	牛蒡子;大力子\|牛蒡	牛蒡根	云南药材标准：第二册\|西藏昌都市洛隆县	祛风清热，解毒消肿，力气通便。用于咽喉肿痛，牙龈肿痛，咳嗽痰稠，腹胀便秘，消渴；黄白带下，干血痨，产后少乳，风毒面肿，大头风，疮疡肿痛\|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin.
TCMBANKHE005628/YEM-121	Fructus Chaenomelis\|Chaenomeles speciosa (Sweet) Nakai	木瓜\|皱皮木瓜	木瓜	云南民族药物志：第一卷	To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema.	傣族/景颇族/苗族/彝族/藏族
TCMBANKHE006892/YEM-215/XU-360	Wikstroemia indica\|Wikstroemia indica (L.)C.A. Mey.	了哥王根\|了哥王	了哥王	云南民族药物志：第二卷\|广西崇左市天等县	To clear heat, disinhibit urine, resolve toxin, break accumulation and kill worms./Pertussis, rheumatic arthritis, leprosy, bronchial asthma, amebic dysentery, pneumonia, epidemic parotitis, edema, scrofula, toxin swelling of sores, swelling and pus of sores, knocks and falls.	傣族/德昂族/景颇族/傈僳族/苗族/瑶族/壮族
TCMBANKHE004517/YEM-793	Hemsleya macrosperma\|Hemsleya macrosperma C.Y.Wu ex C.Y.Wu et C.L.Chen.	大籽雪胆\|罗锅底	苦金盆	云南民族药物志：第四卷	See Hemsleya amabilis./See Hemsleya amabilis.	傣族/苗族/佤族

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000298	SOD1	ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer	superoxide dismutase 1
TCMBANKGE000313	JUN	AP-1; AP1; c-Jun; cJUN; p39	Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000820	CFLAR	CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP	CASP8 and FADD like apoptosis regulator
TCMBANKGE000866	PRKCB	PKC-beta; PKCB; PKCI(2); PKCbeta; PRKCB1; PRKCB2	protein kinase C beta
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE006270	TRAF1	EBI6; MGC:10353	TNF receptor associated factor 1
TCMBANKGE009127	BCL2A1	ACC-1; ACC-2; ACC1; ACC2; BCL2L5; BFL1; GRS; HBPA1	BCL2 related protein A1
TCMBANKGE015072	PNLIP	PL; PNLIPD; PTL	pancreatic lipase