Compound Summary


  Compound Information

药名:

D-Asparaginsaeure

别名:

(R)-Aspartic acid; Tocris-0213; Lopac-A-9256; (2R)-2-aminosuccinic acid; NCGC00024498-01; aspartic acid D-form; Biomol-NT_000167; (2R)-2-aminobutanedioic acid; (R)-2-aminobutanedioic acid; C00402; NCGC00015104-01; PDSP1_001545; NCGC00024498-03; (-)-Aspartic acid; (R)-2-aminosuccinic acid; Aspartic acid, D-; InChI=1/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9; BPBio1_001126; PDSP2_001529; 219096_ALDRICH; NCGC00024498-02; BRN 1723529; CHEBI:17364; NSC 97922; EINECS 217-234-6; (R)-(−)-Aminosuccinic acid;AC1O70SP; (3S)-3-amino-4-oxobutanoic acid; (S)-3-Formyl-beta-alanine; AKOS006351600; SCHEMBL8536

分子式:

C13H15NO6

Smiles:

C(C(C(=O)O)N)C(=O)O

成分:

HBIN022707;HBIN017124

OB_score:

70.568356

CAS_id:

3160-47-2

SymMap_id:

SMIT11392;SMIT01788

TCMID_id:

23532

TCMSP_id:

MOL010336

PubChem_id:

83887

DrugBank_id:

DB00128


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000047 Plastrum Testudinis Praparata 制龟板 Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi), Sea-ear sh/Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi),
TCMBANKHE000098 Colla carapacis et plastri testudinis 龟板胶 Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi), Sea-ear sh/Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi),
TCMBANKHE001819 Plastrum Testudinis 龟板 Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi), Sea-ear sh/Treatment of hyperactivity of liver yang due to deficient yin of the liver and kidneys manifested as dizziness, distension and pain in the head and blurred vision. Tortoise plastron (Guiban) is used with White peony root (Baishao), Cyathula root (Niuxi),
TCMBANKHE002151 Massa Fermentata Rhizpma Pinelliae 半夏曲
TCMBANKHE002223 Semen Sesami 芝麻 Treatment of dizziness, blurred vision, tinnitus, impaired hearing, premature greying of the hair and beard, loss of hair after a serious disease, constipation./Treatment of dizziness, blurred vision, tinnitus, impaired hearing, premature greying of the hair and beard, loss of hair after a serious disease, constipation.
TCMBANKHE002636 独角莲
TCMBANKHE002659 Concretio Silicea Bambusae 天竺黄 For desolving phlegm
TCMBANKHE002700 Cornu Saigae Tataricae 羚羊角 Treatment of high fever with convulsion and impairment of consciousness, eclompsia, epilepsy, mamia, headache and dizziness, redness of the eye with corneal opacity, epidemic fibrile diseases with eruption, carbuncle, abscess and sores./1. Intraperitoneal injection of its alcoholic extract (0.05mg/g) exerts sedative effect in mice.2. Its alcoholic extract and hydrolsate lower vaccine-induced fever in rabbits.3. Analgesic, anti-convulsive and hypotensive.
TCMBANKHE002704 Matrinum 苦参碱
TCMBANKHE003087 建曲 Food digestion
TCMBANKHE005949 Rhizoma Polygoti 黄精 To reinforce qi and nourish yin, to invigorate the function of the spleen, to moisten the lung, and to benefit the kidney./Yin vacuity taxation cough, lung heat dry cough, fatigue hypodynamia due to spleen vacuity, reduced food intake with dry mouth, diabetes mellitus, limp aching lumbus and knees due to kidney yin vacuity, impotence and emission, tinnitus and dim vision, premature graying in beard and hair, vacuity and marked emaciation, wind lai lichen.
TCMBANKHE004803 Radix Rubiae 茜草 To remove heat from blood and arrest bleeding, to eliminate blood stasis, and to stimulate menstrual discharge./1. Hemostatic. 2. Bacteriostatic in vitro. 3. Antitussive and expectorant.
TCMBANKHE008901 Radix Pseudostellariae 太子参 To replenish qi and invigorate the spleen function, and topromote fluid secretion and moisten the lung./Treatment of hypofunction of the spleen with lassitude and anorexia, debility and deficiency of qi and yin marked by spontaneous sweating and thirst during convalescence dry cough due to dryness of the lung.
TCMBANKHE005182 Changium smyrnioides 明党参 To moisten lung and transform phlegm, nourish yin and harmonize stomach, resolve toxin./Lung heat cough, vomiting nausea, reduced food intake with dry mouth, anemia, dizziness, leukorrhea, clove toxin sores.
TCMBANKHE006504 Gallus gallus domesticus 鸡内金 To fortify spleen and disperse food, rough essence and arrest emission, disperse concretion and transform stone./Indigestion, food stagnation, vomiting nausea, diarrhea and dysentery, child gan accumulation, emission, enuresis, frequent urination, calculus of urinary system, gallstones, amenorrhea with concretion and conglomeration, throat impediment with nipple moth, gan of teeth and gum, mouth sore.
TCMBANKHE006755 Herba Hyperici japonici 田基黄;地耳草 1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema./Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls.
TCMBANKHE006428 Herba Cistanches 肉苁蓉 To reinforce the kidney, replenish vital essence and blood, and induce Taxation./Impotence, infertility, backache, limp aching lumbus and knees, weakness in sinews and bones, intestinal dry and constipation.
TCMBANKHE008228 Bubalus bubalis 水牛角 To clear heat, resolve toxin, cool blood, settle fright./Headache due to febrile disease, ardent fever with clouded spirit, macular eruption and papules, blood ejection, spontaneous external bleeding, stasis heat yellowing, infant fright wind, swelling pain in throat, mouth and tongue sores.
TCMBANKHE008996 Agaricus bisporus 双孢蘑菇 See Agaricus campestris./See Agaricus campestris.
TCMBANKHE008227 Ficus simplicissima 粗叶榕 To fortify spleen and supplement lung, move qi and disinhibit damp, soothe sinews and quicken network vessels./Spleen vacuity edema, reduced food intake with fatigue, tuberculosis with cough, vaginal discharge, night sweating, postpartum scant milk, wind-damp impediment pain, edema, cirrhosis with ascites, hepatitis, knocks and falls.
TCMBANKHE006664/YNS-181/XU-60/XU-236 Fructus Arctii lappae|Arctium lappa L.|Arctium lappa 牛蒡子;大力子|牛蒡 牛蒡根 云南药材标准:第二册|西藏昌都市洛隆县 祛风清热,解毒消肿,力气通便。用于咽喉肿痛,牙龈肿痛,咳嗽痰稠,腹胀便秘,消渴;黄白带下,干血痨,产后少乳,风毒面肿,大头风,疮疡肿痛|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin.
TCMBANKHE004548/YEM-392 Radix Liriopes|Liriope spicata(Thunb.)Lour. 山麦冬 土麦冬 云南民族药物志:第二卷 Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine./Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine. 德昂族/水族/彝族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE008422/YNS-215/YEM-751/XU-85/XU-86/XU-593 Ageratum conyzoides|Ageratum conyzoides L.|Ageratum conyzoides L. 胜红蓟|藿香蓟 胜红蓟 云南药材标准:第六册|云南民族药物志:第四卷|广东省廉江市石岭镇 疏风清热,解毒止痒,止血。用于感冒发热,喉咙肿痛,疮疖,湿疹,崩漏。|To clear heat and resolve toxin, stanch bleeding, relieve pain./Common cold with fever, swelling pain in throat, hemoptysis, spontaneous external bleeding, flooding and spotting, pain in stomach duct and abdomen, wind-damp impediment pain, knocks and falls, bleeding due to external injury, swelling toxin of welling abscess and sore, eczema titillation. 傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000241 CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 caspase 8
TCMBANKGE000665 CASP6 MCH2 caspase 6
TCMBANKGE000729 CASP1 ICE; IL1BC; P45 caspase 1
TCMBANKGE000820 CFLAR CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP CASP8 and FADD like apoptosis regulator
TCMBANKGE001155 CASP7 CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 caspase 7
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE013390 CASP2 CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57 caspase 2