Compound Summary


  Compound Information

药名:

CIR

别名:

C00327; EINECS 206-759-6; (2S)-2-amino-5-(carbamoylamino)pentanoic acid; (2S)-2-amino-5-ureidopentanoic acid; C7629_SIGMA; (2S)-2-amino-5-ureido-pentanoic acid; Citrulline, L-; alpha-Amino-delta-ureidovaleric acid; NSC 27425; (2S)-2-amino-5-(aminocarbonylamino)pentanoic acid; Ornithine, N5-(aminocarbonyl)-; N5-(Aminocarbonyl)ornithine; Ornithine, N5-carbamoyl-, L- (8CI); N(5)-(aminocarbonyl)-L-ornithine; SBB012374; N(delta)-Carbamylornithine; N(5)-carbamoyl-L-ornithine; (2S)-2-amino-5-ureido-valeric acid; (S)-2-Amino-5-ureidopentanoic acid; SMP1_000146; 2-Amino-5-ureidovaleric acid; NCGC00142602-01; L-2-Amino-5-ureidovaleric acid; delta-Ureidonorvaline; CHEBI:16349; citrulline; AB1007188; AC1LCUKE; d-citrullin; AK-58500; (R)-2-Amino-5-ureidopentanoic acid; MFCD00216469; KB-49607; D-Citruline; AX8031821; D-Ornithine,N5-(aminocarbonyl)-; W-204205; H-D-Orn(carbamoyl)-OH; (2R)-5-(aminocarbonylamino)-2-azanyl-pentanoic acid; DTXSID90348463; MolPort-003-928-964; 594C519; H-D-Cit-OH; D-Citrulline, >=99.0%; CTK4C0068; N(5)-carbamoyl-D-ornithine; AmbotzHAA1014; AJ-33795; AB0012765; ST24035348; ACM13594520; D-Citrulline; A807006; PubChem17499; TC-108738; J-300336; CHEBI:49007; SC-10122; C6H13N3O3; SCHEMBL437142; ANW-19993; AM82460; AS-12983; GTPL4683; ZINC2166829; FT-0659369; 13594-51-9; B-7191; D0V2DT; (2R)-2-amino-5-(carbamoylamino)pentanoic acid

分子式:

C6H13N3O3

Smiles:

C(CC(C(=O)O)N)CNC(=O)N

成分:

HBIN020706;HBIN021006

OB_score:

52.960247

CAS_id:

372-75-8

SymMap_id:

SMIT05819;SMIT14702

TCMID_id:

3774

TCMSP_id:

MOL003800

PubChem_id:

9750


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001875 Herba Clinopodii 断血流 To arrest bleeding./Treatment of excessive menstrual discharge, hemorrhage from hysteromyoma, hematuria, epistaxis, gingival bleeding, traumatic bleeding.
TCMBANKHE002363 Salmiacum 硒砂
TCMBANKHE002642 冬瓜子 Phlegm-heat cough, pulmonary welling abscess, intestinal welling abscess, white turbidity, vaginal discharge, beriberi, edema, strangury syndrome.
TCMBANKHE003742 Agaricus campestris 蘑菇 To fortify spleen and promote digestion, calm liver and raise spirit./Non-digestion of food accumulation, torpid intake, scant breast milk, hypertension, fatigued spirit and desire to sleep.
TCMBANKHE003919 Medicago sativa 苜蓿 To clear heat and cool blood, disinhibit damp and abate jaundice./Febrile diseases with vexation and fullness, jaundice, enteritis, dysentery, edema, urethral stone, hematochezia from hemorrhoids.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE008355 Polypodium niponicum 水龙骨 To clear heat and disinhibit damp, quicken blood and free network vessels./Opacity of urine, diarrhea, strangury, wind-damp impediment pain, knocks and falls.
TCMBANKHE004907 连钱草 Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE005507 Radix Phytolaccae 商陆 To cause drastic purgation and also diuresis, to counteract toxicity, and to reduce modulation./Edema distention fullness, urinary and fecal stoppage, swelling toxin of welling abscess and sore.
TCMBANKHE008834 Radix seu Rhizoma rdostachyos 甘松 To regulate the flow of qi and relieve pain, and to invigorate the spleen function./Stomachache, distention fullness in chest and abdomen, headache, hysteria, beriberi.
TCMBANKHE006021 Semen Sesami Nigrum 黑芝麻 To tonify the liver and the kidney, to replenish vital essence and blood, and to relax the bowels./Dizziness, tinnitus and deafness, premature graying in beard and hair, hair loss during convalescence, intestinal dry and constipation.
TCMBANKHE008343 Radix Trichosanthis 天花粉 To remove heat, to promote the production of body fluid, and to facilitate the drainage of pus and the subsidence of swelling./Febrile diseases thirst, lung heat dry cough, diabetes mellitus due to internal heat, toxin swelling of sores, induce abortion.
TCMBANKHE007295 Radix Aucklandiae 木香 To relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. /Distending pain in chest and stomach duct, diarrhea and tenesmus, non-digestion of food accumu lation, no thought of food and drink.
TCMBANKHE007751 Cortex Fraxini 秦皮 To remove damp-heat, to arrest discharges, and to improve eyesight./1. Inhibiting the growth of dysentery bacillus and staphylococcus.2. Antitussive and expectorant.3. Aesculin, one of its active components, prolongs the hypnotic effect of hexobarbital in mice.4. Aescuktin, another active component, exerts an antihistaminic effect and relaxes smooth muscles of guinea-pig's trachea in vitro.5. Analgesic. The effect of aescuktin is stronger than that of aspirin but weaker than codeine.
TCMBANKHE006143/YEM-213 Luffa cylindrica|Luffa cylindrica(L.)Roem. 丝瓜 丝瓜 云南民族药物志:第二卷 To clear heat and resolve phlegm, cool blood and resolve toxin./Febrile diseases with vexation and thirst, cough of phlegm asthma, intestinal wind bleeding, bleeding from hemorrhoids, blood strangury, flooding and spotting, sores with welling abscess and flat abscess, galactostasis, innominate toxin swelling, edema. 阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/藏族
TCMBANKHE004905/YNS-291/YEM-267/XU-217 Diospyros kaki|Diospyros kaki Thumb.var. silvestris Makino|Diospyros kaki Thunb.|Diospyros kaki var. silvestris 柿子|野柿|柿 野柿根|柿 云南药材标准:第五册|云南民族药物志:第二卷|广西省桂林市荔浦县蒲芦乡天河瀑布景区外 调补四塔,补土健胃,增性强身,清火解毒,用于气虚喘咳,神疲乏力,不思饮食,性欲减退,早衰,胆汁病()|To clear heat, engender liquid, moisten lung, resolve toxin./Cough, heat vexation and thirst, blood ejection, mouth sore, heat dysentery, hematochezia. 傣族/哈尼族/傈僳族/苗族/水族/佤族/彝族
TCMBANKHE004220/YEM-273 Datura metel|Datura metel L. 曼陀罗子|洋金花 洋金花 云南民族药物志:第二卷 To calm asthma, dispel wind, relieve pain./Cough and asthma, fright epilepsy, wind-cold-damp impediment, dysentery, prolapse of rectum, knocks and falls. 傣族/傈僳族/彝族/壮族
TCMBANKHE004546/YEM-320 Citrullus vulgaris [Syn. Citrullus lanatus ]|Citrullus lanatus(Thunb.)Matsum.et Nakai 西瓜 西瓜 云南民族药物志:第二卷 To clear heat and resolve summerheat, resolve summerheat and engender liquid, disinhibit urine./Summerheat-heat vexation and thirst, exuberant heat fluid damage, inhibited urination, throat impediment, mouth sore. 傣族/佤族/壮族
TCMBANKHE002308/YEM-320 Exocarpium Citrulli|Citrullus lanatus(Thunb.)Matsum.et Nakai 西瓜皮|西瓜 西瓜 云南民族药物志:第二卷 For summer-heat syndrome with fever, thirst and oliguria with yellowish urine and edema./1. An active component, citrulline, raises urea level in blood and in urine, thus promotes diuresis.2. Oral administration of cucurbocitrin, another active component, or its aqueous extract can lower blood pressure and capillary pressure in healthy person. 傣族/佤族/壮族
TCMBANKHE004583/YEM-60/XU-35 Juglans regia|Juglans regia L. 胡桃仁|胡桃|核桃树根 核桃 云南民族药物志:第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 To supplement kidney and boost essence, warm lung and settle asthma, moisten intestines and free stool./Enduring cough and asthma, bronchitis, lumbago and limp leg, frequent urination, enuresis, impotence, emission, intestinal dry and constipation, stone strangury, sores and scrofula. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE006699/YEM-696 Cucurbita moschata|Cucurbita moschata(Duch.ex Lam.)Duch.ex Poiret 南瓜 南瓜 云南民族药物志:第四卷 To resolve toxin and disperse swelling./Pulmonary welling abscess, asthma, swollen welling abscess, scalds, poisonous bee stings. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/佤族/彝族
TCMBANKHE006930/YNS-289/YEM-892 Momordica charantia|Momordica charantia L. 苦瓜 野苦瓜叶|苦瓜 云南药材标准:第五册|云南民族药物志:第五卷 清热解毒,消肿排脓,生津止渴,安蛔止痛,用于小儿发热,咽喉肿痛,口舌生疮,脘腹疼痛,蛔虫病,消渴,小便热痛,赤白下痢,疔疮痈结,鹅掌风,虫蛇咬伤。|To dispel summerheat, brighten eyes, resolve toxin./Summerheat-heat vexation and thirst, diabetes mellitus, painful red eyes, dysentery, swelling toxin of sore and welling abscess. 傣族/基诺族/佤族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2