Compound Summary


  Compound Information

药名:

1H,3H-Pyrano(3,4-c)pyran-1-one, 5-ethenyl-6-(beta-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-, (4aS-(4aalpha,5beta,6alpha))-;sweroside

别名:

(4aS,5R,6S)-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-5-vinyl-4,4a,5,6-tetrahydro-3H-pyrano[5,4-c]pyran-1-one; ACon1_000233; (4aS,5R,6S)-5-ethenyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,6-tetrahydro-3H-pyrano[5,4-c]pyran-1-one; 14215-86-2; (4aS,5R,6S)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-5-vinyl-4,4a,5,6-tetrahydro-3H-pyrano[5,4-c]pyran-1-one; ACon0_001457; (4aS,5R,6S)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-5-vinyl-4,4a,5,6-tetrahydro-3H-pyrano[5,4-c]pyran-1-one; MEGxp0_000813

分子式:

C16H22O9

Smiles:

C=CC1C2CCOC(=O)C2=COC1OC3C(C(C(C(O3)CO)O)O)O

成分:

HBIN002554;HBIN045174

OB_score:

4.955221

CAS_id:

14215-86-2

SymMap_id:

SMIT03199;SMIT01632

TCMID_id:

20487

TCMSP_id:

MOL000650

PubChem_id:

161036


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000262 Swertia chirata
TCMBANKHE001763 Ophiorrhiza liukiuensis 琉球蛇根草
TCMBANKHE001868 Lonicera quinquelocularis
TCMBANKHE002046 金果揽 See Tinospora sagittata .
TCMBANKHE003589 Tripterospermum japonicum 日本双蝴蝶茶花 See Tripterospermum taiwanense./See Tripterospermum taiwanense.
TCMBANKHE003723 Flos Lonicerae 金银花 To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003771 Gentiana dahurica 达乌里秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE003783 Fructus Corni 枣皮 Treatment of dizziness, tinnitus, soreness in the loins and knees, impotence, seminal emission, enuresis, frequency of urination, excessive uterine bleeding and leukorrhea, collapse with profuse sweating, diabetes./1. Relieving cyclophosphamide-induced leukopenia in mice.2. Diuretic and hypotensive3. Inhibiting the growth of Bacillus dysenteriae in vitro.
TCMBANKHE003801 Swertia calycina 苞萼獐牙菜
TCMBANKHE003804 Swertia pseudochinensis 獐牙菜 To drain fire and resolve toxin, disinhibit damp, fortify spleen./Acute icterohepatitis, chronic liver diseases, damp-heat jaundice, dysentery, gastritis, indigestion, acute conjunctivitis, toothache, mouth sore, swelling pain of sores.
TCMBANKHE003952 Folium Rhododendri Daurici 满山红 Acute bronchitis, chronic bronchitis.
TCMBANKHE005721 Swertia chinensis 当药 To clear heat and resolve toxin, disinhibit damp and fortify stomach./Medullitis, pharyngolaryngitis, tonsillitis, conjunctivitis, hepatitis, indigestion, dysentery, sore and welling abscess with scab and lichen, poisonous snake bites.
TCMBANKHE004053 Sinoadina racemosa [Syn. Adina racemosa ] 鸡子木
TCMBANKHE004098 Herba Swertiae 青叶胆 To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis.
TCMBANKHE007954 Flos Rhododendri Mollis 闹羊花 To relieve rheumatic conditions, and to eliminate blood stasis and alleviate pain./Tachycardia, palpitation, hypertension, wind-damp impediment pain, knocks and falls, intractable lichen.
TCMBANKHE004340 萱草根 Edema, jaundice, strangury-turbidity, vaginal discharge, spontaneous external bleeding, hematochezia, flooding and spotting, scrofula, mammary welling abscess, galactostasis.
TCMBANKHE009149 Swertia angustifolia 狭叶獐牙菜
TCMBANKHE007224 Tripterospermum taiwanense 台湾双蝴蝶 To clear heat and resolve toxin, suppress cough./Jaundice, wind-heat cough.
TCMBANKHE005606 Gentiana crassicaulis 粗茎秦艽 See Gentiana macrophylla./See Gentiana macrophylla.
TCMBANKHE005640 Swertia erythrosticta 红直獐牙菜 To clear heat and resolve toxin, disinhibit damp and abate jaundice, kill worms./Wind-heat cough, sore swollen throat, jaundice (icterus, ICT), syphilis, swelling and toxin of sore and welling abscess, scab and lichen.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE008683/XU-650 Swertia macrosperma 大籽獐牙菜 云南省昆明市呈贡区梁王山
TCMBANKHE007107 Swertia pubescens 毛獐牙菜
TCMBANKHE008332 绵萆薢 Strangury with white turbidity, excessive leukorrhea, damp-heat sore toxin, impediment pain in lumbus and knees.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE009045 Swertia fasciculata 簇花獐牙菜
TCMBANKHE007353 Gentiana lactea 乳白龙胆
TCMBANKHE007856 Swertia nervosa 显脉獐牙菜 To clear heat and resolve toxin, quicken blood and regulate menstruation./Jaundice (icterus, ICT), bitter taste, tidal fever.
TCMBANKHE008003 Swertia franchetiana 抱茎獐牙菜
TCMBANKHE003774/XU-523 Swertia cincta 西南獐芽菜|西南獐牙菜 四川省凉山州宁南县
TCMBANKHE007892/YNS-331 Swertia punicea|Swertia punicea Hemsl 紫红獐牙菜 紫红青叶胆 云南药材标准:第一册 清肝利胆,清热利湿。用于黄疸尿赤,热淋涩痛。|To clear liver and disinhibit gallbladder, clear heat and resolve toxin, disinhibit damp./Acute icterohepatitis, cholecystitis, wind-heat common cold, wind-fire toothache, swelling pain in throat, indigestion, acute bacillary dysentery, infection of urinary system, tinnitus and deafness, burns and scalds.
TCMBANKHE004162/YEM-17 Catharanthus roseus|Catharanthus roseus (L.) G.Don 长春花 长春花 云南民族药物志:第一卷 To resolve toxin, clear heat and calm liver, anticancer./Hypertension, swelling toxin of welling abscess and sore, scalds.
TCMBANKHE000196/YEM-180 Bulbus Lilii Preparata|Lilium brownii F. E. Brown. ex Miellez 炙百合|百合 野百合 云南民族药物志:第一卷 1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpitation and absent-mindedness)./1. To moisurize the lung and relieve cough (lung-dryness with cough and hemoptysis). 2. To relieve cardiac heat and tranquilize the mind (convalescence of febrile diseases or yin-deficiency with heat manifested as irritability, insomnia, dreaminess, palpi 哈尼族/傈僳族/彝族
TCMBANKHE005867/YEM-91 Lonicera japonica|Lonicera japonica Thunb. 忍冬藤|金银花 金银花 云南民族药物志:第一卷 To clear heat and resolve toxin, free network vessels./Warm disease fever, swelling toxin of sore and welling abscess, heat toxin blood dysentery, wind-damp-heat impediment. 阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/纳西族/佤族/瑶族/彝族/壮族
TCMBANKHE007630/YEM-983 Dipsacus asperoides|Dipsacus asperoides C.Y.Cheng et T.M.Ai 川续断 续断 云南民族药物志:第五卷 To supplement liver and kidney, strengthen sinews and bones, joint bones, check flooding and spotting./Limp aching lumbus and knees, wind-damp impediment pain, flooding and spotting, profuse menstruation, fetal bleeding, knocks and falls. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族
TCMBANKHE006587/YEM-983 Radix Dipsaci|Dipsacus asperoides C.Y.Cheng et T.M.Ai 续断|川续断 续断 云南民族药物志:第五卷 For tonifying yang/See Dipsacus asperoides. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001818 NQO2 DHQV; DIA6; NMOR2; QR2 N-ribosyldihydronicotinamide:quinone reductase 2
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1