Compound Summary

  Compound Information

TCMBANKIN058079

药名:	ampelopsin
别名:	(2R-trans)-2,3-Dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; Flavanone, 3,3',4',5,5',7-hexahydroxy-; 27200-12-0; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; (+)-Dihydromyricetin; C02906; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4-chromanone; (+)-Ampelopsin; (2R,3R)-3,5,7,3',4',5'-hexahydroxyflavanone; Dihydromyricetin; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R-trans)-; Ampelopsin (flavanol); Ampelopsin; CHEBI:28429; 3,3',4',5,5',7-Hexahydroxy-2,3-dihydroflavanonol; (2R-trans)-2,3-Dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; LS-39586; 27200-12-0; HY-N0112; NCGC00346604-01; Dihydromyricetin, >=98% (HPLC); KS-000001HH; MFCD00189451; UNII-KD8QND6427; AN-8425; CHEBI:28429; AC-8004; 3,3',4',5,5',7-Hexahydroxy-2,3-dihydroflavanonol; (2r,3r)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one; C15H12O8; (2R,3R)-3,3',4',5,5',7-hexahydroxy-2,3-dihydroflavanonol; AJ-47993; TR-031359; (+)-Ampelopsin; KD8QND6427; AK160312; Ampelopsin (flavanol); MolPort-006-069-341; AX8114231; AB0020621; AC1Q6KIA; V1568; (2R,3R)-3,5,7,3',4',5'-hexahydroxyflavanone; rac-ampelopsin; CHEMBL3348861; BDBM212434; AKOS022168215; (2R,3R)-2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; C02906; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-4H-chromen-4-one; M-1204; AC1L4PNK; 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R,3R)-; Bio-0899; DTXSID50181676; Dihydromyricetin, analytical standard; Dihydromyricetin; 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R-trans)-; Dihydromyricetin (diH-Myr); CD0156; ZINC100037633; ST24045966; Ampeloptin; CTK8E2644; CS-3809; BG01609529; Flavanone, 3,3',4',5,5',7-hexahydroxy-; Dihydromyricetin (Ampeloptin); SCHEMBL723736; 2B89FBAC-4DD1-44C9-BE2A-9D0C173BDFD8; (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one; s2399; Q-100341; Dihydromyricetin - Ampeloptin; FT-0686596; (+)-Dihydromyricetin;
分子式:	C15H12O8
Smiles:	C1=C(C=C(C(=C1O)O)O)C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O
成分:	HBIN015890;HBIN023933;HBIN015902;HBIN023933
OB_score:	23.476859
CAS_id:	27200-12-0
SymMap_id:	SMIT00329; SMIT18905
TCMID_id:	1074;32748;25582
TCMSP_id:	MOL013374
PubChem_id:	161557
DrugBank_id:	DB15645

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001390		无莿根
TCMBANKHE003755	Radix Ampelopsis	白蔹			To remove toxic heat, to cure carbuncles, and to reduce nodules./Swelling toxin of sore and welling abscess, burns and scalds, scrofula, damp sore, warm malaria, frightepilepsy, blood dysentery, intestinal wind, hemorrhoids and fistulas, leukorrhea, knocks and falls, bleeding due to external injury.
TCMBANKHE005968	Cedrus atlantica	北非雪松
TCMBANKHE006493	Schisandra chinensis	五味子			To promote contraction and secure astriction, boost qi and engender liquid, quiet heart and spirit./Enduring cough and vacuity asthma, dream emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating and night sweating, fluid damage and thirst, palpitation and insomnia.
TCMBANKHE005221	Semen Ginkgo	白果			1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE005252		枳椇子			Drunkenness, vexation and thirst, vomiting, inhibited urine and stool.
TCMBANKHE005325	Galla Chinensis	五倍子			To remove heat from the lung, to arrest cough, diarrhea, excessive sweating, bleeding and exudation from sores./1. Astringent, antidiarrheal, haemostatic and antibacterial.2. Acting as a detoxicating agent by combining with various ions of heavy metals, alkaloids or glycosides to form insoluble compounds.
TCMBANKHE006099		桑白皮			Lung heat cough asthma, water-rheum collecting lung, distention fullness and rapid asthma, edema, beriberi, inhibited urination.
TCMBANKHE007751	Cortex Fraxini	秦皮			To remove damp-heat, to arrest discharges, and to improve eyesight./1. Inhibiting the growth of dysentery bacillus and staphylococcus.2. Antitussive and expectorant.3. Aesculin, one of its active components, prolongs the hypnotic effect of hexobarbital in mice.4. Aescuktin, another active component, exerts an antihistaminic effect and relaxes smooth muscles of guinea-pig's trachea in vitro.5. Analgesic. The effect of aescuktin is stronger than that of aspirin but weaker than codeine.
TCMBANKHE008354	Semen Ginkgo	白果			1. To strengthen lung qi and soothe asthma; 2. To relieve leukorrhea/AD syndrome, primary degenerative dementia of Alzheimer disease, multi-infarct dementia, improving cognitive function in elderly dementia patients, stable intermittent claudication, cerebrovascular insufficiency diseases, cough with profuse phlegm, vaginal discharge, enuresis and frequent urination.
TCMBANKHE007061	Ampelopsis megalophylla	大叶蛇葡萄			To clear heat and disinhibit damp, calm liver and lower blood pressure, quicken blood and free network vessels./Dysentery, diarrhea, dribbling pain of urination, hypertension, dizzy head and distention eyes, knocks and falls.
TCMBANKHE007176	Fagopyrum tataricum	苦荞麦
TCMBANKHE008602	Cercidiphyllum japonicum	日本连香树			To dispel wind and settle fright, check tetany./Infant fright wind, convulsion with cold limbs.
TCMBANKHE008466	Rhododendron cinnabarinum	朱砂杜鹃
TCMBANKHE005899/XU-345	Spina gleditsiae;Spi gleditsiae|Gleditsia sinensis	皂刺;皂角刺|皂荚		云南省曲靖市会泽县	Treatment of carbuncle and boil at the early stage or formation of abscess difficult to burst, external use for scabies and leprosy. /1. To relieve carbuncle and drain pus. For the early stage of carbuncle or carbuncle with unruptured abscess. 2. To expel wind and kill parasites. For tinea infection and leprosy.
TCMBANKHE007915/XU-570	Ampelopsis grossedentata [Syn. Ampelopsis cantoniesis var. grossedentata ]|Ampelopsis grossedentata	显齿蛇葡萄		广西省百色市靖西市	To clear heat and resolve toxin, disinhibit damp and disperse swelling./Common cold with fever, swelling pain in throat, icterohepatitis, red eyes with gall, swollen sore of welling abscess and boil.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000048

Neoplasms

group

Neoplasms

22251058

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000135	CXCR4	CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS	C-X-C motif chemokine receptor 4
TCMBANKGE000251	FGF2	BFGF; FGF-2; FGFB; HBGF-2	fibroblast growth factor 2
TCMBANKGE000279	SPHK1	SPHK	sphingosine kinase 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000987	COL11A2	DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3	collagen type XI alpha 2 chain
TCMBANKGE001106	MTOR	FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS	mechanistic target of rapamycin kinase
TCMBANKGE001147	CDH1	Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO	cadherin 1
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001198	BECN1	ATG6; VPS30; beclin1	beclin 1