Compound Summary


  Compound Information

药名:

mangiferin

别名:

Chinoinin; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]xanthone; AIDS-073319; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]xanthen-9-one; (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol; C10077; 1,3,6,7-tetrahydroxyxanthone C2-beta-D-glucoside; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-9-xanthenone; 4773-96-0; BCBcMAP01_000240; AIDS073319; M3547_SIGMA; 2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one; SMP1_000290; 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one; Mangiferin; Mangiferin Mangifera indica bark; CHEBI:6682

分子式:

C19H18O11

Smiles:

C1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=C(C(=C3)O)C4C(C(C(C(O4)CO)O)O)O)O

成分:

HBIN034394

OB_score:

13.705346

CAS_id:

4773-96-0

SymMap_id:

SMIT01501; SMIT06436

TCMID_id:

13474

TCMSP_id:

MOL004525

PubChem_id:

5281647


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000481 Pyrrosia pseudocalvata
TCMBANKHE000747 Hypericum ancherii
TCMBANKHE001367 Semen Hyoscyami 天仙子 To relieve spasm and pain, and to cause tranquilization./1. Antisudorific, saliva antisecretory and mydriatic.2. Relaxing the smooth muscles.3. Increasing heart rate and exciting the respiratory center.
TCMBANKHE002083 石见穿
TCMBANKHE003222 Folium Viticis Negundo 牡荆叶 To counteract toxicity, and to induce expectoration, relieve cough and asthma./1. Oral administration of its eemulsion (0.52-1.73g.kg) exerts a strong expectorant effect in mice.2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.3. Increasing the hypnotic effect of pentobarital sodium in mice.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE005226 Rhizoma Dryriae 骨碎补 To replenish the kidney, to strengthen the bones, to promote the healing of fracture, and to relieve pain./Kidney vacuity lumbago, tinnitus and deafness, tooth mobilizing, wrenching and contusion from knocks and falls, sinew and bone wound, alopecia areata, white patch wind.
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE004561 Crocus sativus 臧红花 To quicken blood and transform stasis, dissipate depression and open binds./Anxiety and depression, glomus and oppression in chest and diaphragm, blood ejection, cold damage mania, fright palpitation, amenorrhea, postpartum blood stasis abdominal pain, painful swelling from knocks and falls.
TCMBANKHE004743 Pyrrosia petiolosa 有柄石韦 See Pyrrosia lingua./See Pyrrosia lingua.
TCMBANKHE008734 omphalia 雷丸 To kill worms./1. Its proteolytic enzyme is a taeniacidal agent. 2. Its alcoholic extract is an ascaricide.
TCMBANKHE005448 Pyrrosia calvata 光石韦
TCMBANKHE005496 Pyrrosia davidii 北京石韦 See Pyrrosia lingua./See Pyrrosia lingua.
TCMBANKHE005497 Rhizoma Belamcandae 射干 To remove toxic heat, eliminate phlegm, and soothe the sore throat./Heat toxin and phlegm-fire stasis, swelling pain in throat, cough and asthma.
TCMBANKHE007497 Swertia mussotii 川西獐牙菜 To clear liver and disinhibit gallbladder, abate jaundice, disinhibit water and disperse edema./Acute icterohepatitis, hepatitis, cholecystitis, edema.
TCMBANKHE006641 Calculus Bovis 牛黄 To restore consciousness by reducing fire and eliminating phlegm , to relieve convulsions, and to counteract toxicity./Ardent fever, coma, fright epilepsy, convulsion, febrile diseases clouded spirit, wind stroke with orifice block, acute infant fright wind, swelling pain in throat, mouth and tongue sores, welling abscess and flat abscess with clove sore.
TCMBANKHE006866 杧果核
TCMBANKHE007172 Mangifera persiciformis 扁桃 See Mangifera indica./See Mangifera indica.
TCMBANKHE007449 Salacia prinoides [Syn. Salacia chinensis] 桫拉木 To expel wind and eliminate damp, free channels and quicken blood./Wind-damp impediment, blood stasis lumbago.
TCMBANKHE008003 Swertia franchetiana 抱茎獐牙菜
TCMBANKHE008687 Rhizoma Anemarrhee 知母 To remove heat and quench fire, and to promote the production of body fluid and relieve dryness syndromes./Diabetes mellitus, warm heat disease, ardent fever with vexation and thirst, cough and asthma, dry cough, constipation, steaming bone tidal fever, vacuity vexation and insomnia, strangury-turbidity.
TCMBANKHE006668/YEM-19 Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng. 白木香 沉香 云南民族药物志:第一卷 See Aquilaria agallocha./See Aquilaria agallocha . 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE007246/YEM-255 Pyrrosia sheareri|Pyrrosia sheareri( Baker )Ching 庐山石韦 庐山石韦 云南民族药物志:第二卷 See Pyrrosia lingua./See Pyrrosia lingua. 苗族/彝族/藏族
TCMBANKHE005548/YEM-255 Pyrrosia sheareri( Baker )Ching 石韦|庐山石韦 庐山石韦 云南民族药物志:第二卷 Heat strangury, blood strangury, stone strangury, urinary stoppage, dripping with inhibited pain, blood ejection, nosebleed(epistaxis), hematuria, flooding and spotting, lung heat cough asthma, urethral stone, urinary tract infection, bleeding. 苗族/彝族/藏族
TCMBANKHE006849/YEM-65 Gentiana rhodantha|Gentiana rhodantha Franch.ex Hemsl. 红花龙胆 红花龙胆 云南民族药物志:第一卷 To clear heat and disinhibit damp, cool blood and resolve toxin./Cough and asthma due to lung heat, consumption cough with phlegm and blood, jaundice, dysentery, bloody stool, inhibited urination, postpartum fever, infant fright wind, gan accumulation, toxin swelling of sores, burns and scalds, snake bite. 哈尼族/傈僳族/藏族
TCMBANKHE007819/YEM-691 Mangifera indica|Mangifera indica L. 杧果叶|杧果 杧果 云南民族药物志:第四卷 To allay thirst, transform stagnation, relieve itch./Gan accumulation, diabetes mellitus, eczema titillation, wart. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族
TCMBANKHE008634/YEM-691 Mangifera indica|Mangifera indica L. 杧果树皮|杧果 杧果 云南民族药物志:第四卷 To clear summerheat heat, stanch bleeding, resolve sore toxin./Summerheat damage, generalized fever and aversion to cold. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族
TCMBANKHE006555/YEM-691 Mangifera indica|Mangifera indica L. 杧果 杧果 云南民族药物志:第四卷 To boost stomach, engender liquid, check vomiting, relieve cough./Thirst, vomiting, reduced food intake, cough. 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族
TCMBANKHE007805/YEM-855 Urena lobata|Urena lobata L. 地桃花 地桃花 云南民族药物志:第五卷 To dispel wind and disinhibit damp, quicken blood and disperse swelling, clear heat and resolve toxin./Common cold, wind-damp impediment pain, dysentery, diarrhea, strangury syndrome, vaginal discharge, menstrual disorder, painful swelling from knocks and falls, throat impediment, mammary welling abscess, sore and boil, poisonous snake bite. 布朗族/傣族/哈尼族/拉祜族/傈僳族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000298 SOD1 ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer superoxide dismutase 1
TCMBANKGE001141 PPARA NR1C1; PPAR; PPARalpha; hPPAR peroxisome proliferator activated receptor alpha
TCMBANKGE001176 CAT - catalase
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1