Compound Summary
Compound Information
药名: | piceatannol |
别名: | (e)-piceatannol; NCGC00015794-01; 5-[(Z)-2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,3-diol; 5-[(Z)-2-(3,4-dihydroxyphenyl)vinyl]benzene-1,3-diol; Lopac-P-0453; PIT; e-piceatannol; (e)-piceatannol; 5-[(Z)-2-(3,4-dihydroxyphenyl)vinyl]resorcinol; NCGC00094226-05; 5-[(E)-2-(3,4-dihydroxyphenyl)vinyl]resorcinol; KBio3_000859; IDI1_002155; 3,3',4,5'-Tetrahydroxystilbene; 3,3',4,5'-Stilbenetetrol; C05901; EU-0100915; NSC 622471; 1,2-Benzenediol, 4-[2-(3,5-dihydroxyphenyl)ethenyl]-, (E)-; 3,3',4'5-Tetrahydroxystilbene; 5-[2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,3-diol; NSC365798; Lopac0_000915; 5-[2-(3,4-dihydroxyphenyl)vinyl]benzene-1,3-diol; 5-[2-(3,4-dihydroxyphenyl)vinyl]resorcinol; MEGxp0_000245; KBio2_000460; SMP2_000263; trans-3,3′,4,5′-Tetrahydroxystilbene; 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-; 21100-92-5; trans-3,3',4,5'-Tetrahydroxystilbene; 5-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]benzene-1,3-diol; AIDS-160223; (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol; Piceatannol; NSC 365798; 4339-71-3; E-Piceatannol; 3-Hydroxyresveratol; 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol; KBio2_005596; 10083-24-6; NCGC00094226-04; BiomolKI2_000031; 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol; KBioGR_000460; Bio2_000880; KBioSS_000460; NSC622471; KBio2_003028; 5-[(E)-2-(3,4-dihydroxyphenyl)vinyl]benzene-1,3-diol; KBio3_000860; 3,5,3',4'-Tetrahydroxystilbene; 1,2-Benzenediol, {4-[2-(3,} 5-dihydroxyphenyl)ethenyl]-, (E)-; BSPBio_001120; NCGC00094226-02; NCI60_003368; 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-, (E)-; Astringinine; P0453_SIGMA; BiomolKI_000023; AIDS160223; CHEBI:28814; 4-(2-(3,5-Dihydroxyphenyl)vinyl)-1,2-benzenediol; Bio2_000400; 3,3′,4,5′-Tetrahydroxy-trans-stilbene; K00089; ZINC00014036 |
分子式: | C14H12O4 |
Smiles: | C1=CC(=C(C=C1C=CC2=CC(=CC(=C2)O)O)O)O |
成分: | HBIN039816;HBIN040152;HBIN025320;HBIN025319;HBIN011959 |
OB_score: | 82.411914;72.290295 |
CAS_id: | 4339-71-3;10083-24-6 |
SymMap_id: | SMIT04557;SMIT06464 |
TCMID_id: | 28917;17264 |
TCMSP_id: | MOL002284;MOL004570 |
PubChem_id: | 667639;6603962 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE002937 | Vouacapoua macropetala | 长话版克亚树 | ||||
| TCMBANKHE004898 | Smilax menispermoidea | 防己叶菝葜 | See Smilax glabra ./See Smilax glabra . | |||
| TCMBANKHE004347 | Rheum emodi [Syn. Rheum australe] | 藏边大黄 | To clear heat and resolve toxin, stanch bleeding and engender flesh./Lung heat cough, swelling pain in throat, swelling toxin of welling abscess and sore, bleeding due to external injury, hematochezia. | |||
| TCMBANKHE006135 | Rheum wittrocki | 天山大黄 | ||||
| TCMBANKHE005382 | Caragana tibetica | 毛刺锦鸡儿 | ||||
| TCMBANKHE008082 | Picea abies | 欧洲云杉 | ||||
| TCMBANKHE006305 | Phytolacca americana [Syn. Phytolacca decandra ] | 美商陆 | See Phytolacca esculenta./See Phytolacca esculenta. | |||
| TCMBANKHE006313 | Radix et Rhizoma Rhei | 大黄 | To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds. | |||
| TCMBANKHE007131/XU-525 | Rhodomyrtus tomentosa | 桃金娘 | 广西省北海市银海区福成镇 | To nourish blood and stanch bleeding, astringe intestines and secure essence./Blood vacuity and general weakness, blood ejection, nosebleed(epistaxis), taxation damage hemoptysis, hematochezia, flooding and spotting, emission, vaginal discharge, dysentery, prolapse of rectum, scalds, bleeding due to external injury. | ||
| TCMBANKHE007363/YEM-744/XU-850 | Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum | 大黄; 生锦纹; 生军|掌叶大黄 | 掌叶大黄 | 云南民族药物志：第四卷|西藏昌都地区芒康县 | To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect. | 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000097 | IRF3 | IIAE7 | interferon regulatory factor 3 |
| TCMBANKGE000139 | POR | CPR; CYPOR; P450R | cytochrome p450 oxidoreductase |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000224 | AGT | ANHU; SERPINA8; hFLT1 | angiotensinogen |
| TCMBANKGE000276 | NOS1 | IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS | nitric oxide synthase 1 |
| TCMBANKGE000327 | SYK | p72-Syk | spleen associated tyrosine kinase |
| TCMBANKGE000428 | SERPINA1 | A1A; A1AT; AAT; PI; PI1; PRO2275; alpha1AT; nNIF | serpin family A member 1 |
| TCMBANKGE000879 | SERPINE2 | GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI | serpin family E member 2 |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
| TCMBANKGE001038 | SERPINF1 | EPC-1; OI12; OI6; PEDF; PIG35 | serpin family F member 1 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001085 | MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | mitogen-activated protein kinase 8 |
| TCMBANKGE001094 | SIRT3 | SIR2L3 | sirtuin 3 |
| TCMBANKGE001107 | NOS3 | ECNOS; eNOS | nitric oxide synthase 3 |
| TCMBANKGE001108 | BMP2 | BDA2; BMP2A; SSFSC | bone morphogenetic protein 2 |
| TCMBANKGE001170 | CDK4 | CMM3; PSK-J3 | cyclin dependent kinase 4 |
| TCMBANKGE001182 | SIRT1 | SIR2; SIR2L1; SIR2alpha | sirtuin 1 |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE001565 | SERPINA4 | KAL; KLST; KST; PI-4; PI4; kallistatin | serpin family A member 4 |
| TCMBANKGE001755 | MAOB | - | monoamine oxidase B |
| TCMBANKGE002062 | SERPINB6 | CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3 | serpin family B member 6 |
| TCMBANKGE002226 | SERPINB12 | YUKOPIN | serpin family B member 12 |
| TCMBANKGE002987 | SERPIND1 | D22S673; HC2; HCF2; HCII; HLS2; LS2; THPH10 | serpin family D member 1 |
| TCMBANKGE004736 | SERPINA5 | PAI-3; PAI3; PCI; PCI-B; PLANH3; PROCI | serpin family A member 5 |
| TCMBANKGE004875 | SERPINA9 | GCET1; SERPINA11; SERPINA11b | serpin family A member 9 |
| TCMBANKGE006373 | TYW1 | RSAFD1; TYW1A; YPL207W | tRNA-yW synthesizing protein 1 homolog |
| TCMBANKGE006840 | SERPINA12 | OL-64 | serpin family A member 12 |
| TCMBANKGE007137 | SERPINB5 | PI5; maspin | serpin family B member 5 |
| TCMBANKGE007511 | ATP5F1A | ATP5A; ATP5A1; ATP5AL2; ATPM; COXPD22; HEL-S-123m; MC5DN4; MOM2; OMR; ORM; hATP1 | ATP synthase F1 subunit alpha |
| TCMBANKGE007589 | ATP5F1B | ATP5B; ATPMB; ATPSB; HEL-S-271 | ATP synthase F1 subunit beta |
| TCMBANKGE007700 | HMSD | ACC-6; ACC6; C18orf53; HSMD-v | histocompatibility minor serpin domain containing |
| TCMBANKGE007709 | SERPINC1 | AT3; AT3D; ATIII; ATIII-R2; ATIII-T1; ATIII-T2; THPH7 | serpin family C member 1 |
| TCMBANKGE008568 | SERPINB9 | CAP-3; CAP3; PI-9; PI9 | serpin family B member 9 |
| TCMBANKGE009580 | SERPINB2 | HsT1201; PAI; PAI-2; PAI2; PLANH2 | serpin family B member 2 |
| TCMBANKGE009602 | SERPINB4 | LEUPIN; PI11; SCCA-2; SCCA1; SCCA2 | serpin family B member 4 |
| TCMBANKGE009674 | ATP5F1C | ATP5C; ATP5C1; ATP5CL1 | ATP synthase F1 subunit gamma |
| TCMBANKGE009863 | MTRR | MSR; cblE | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| TCMBANKGE009993 | SERPINA7 | TBG; TBGQTL | serpin family A member 7 |
| TCMBANKGE010072 | SERPINB3 | HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A | serpin family B member 3 |
| TCMBANKGE010991 | LCK | IMD22; LSK; YT16; p56lck; pp58lck | LCK proto-oncogene, Src family tyrosine kinase |
| TCMBANKGE011356 | NDOR1 | CIAE1; NR1; bA350O14.9 | NADPH dependent diflavin oxidoreductase 1 |
| TCMBANKGE012032 | SERPINA6 | CBG | serpin family A member 6 |
| TCMBANKGE012677 | ZAP70 | ADMIO2; IMD48; SRK; STCD; STD; TZK; ZAP-70 | zeta chain of T cell receptor associated protein kinase 70 |
| TCMBANKGE012918 | SERPINA10 | PZI; ZPI | serpin family A member 10 |
| TCMBANKGE013393 | PDCD1LG2 | B7DC; Btdc; CD273; PD-L2; PDCD1L2; PDL2; bA574F11.2 | programmed cell death 1 ligand 2 |
| TCMBANKGE013481 | SERPINI2 | MEPI; PANCPIN; PI14; TSA2004 | serpin family I member 2 |
| TCMBANKGE013563 | SERPINA11 | - | serpin family A member 11 |
| TCMBANKGE013681 | SERPINE3 | - | serpin family E member 3 |
| TCMBANKGE013696 | SERPINB7 | MEGSIN; PPKN; TP55 | serpin family B member 7 |
| TCMBANKGE013760 | SERPINA3 | AACT; ACT; GIG24; GIG25 | serpin family A member 3 |
| TCMBANKGE013779 | SERPINB1 | EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2 | serpin family B member 1 |
| TCMBANKGE013869 | SERPINB10 | PI-10; PI10 | serpin family B member 10 |
| TCMBANKGE014065 | SERPINB8 | C18orf53; CAP2; PI-8; PI8; PSS5 | serpin family B member 8 |
| TCMBANKGE014201 | SERPINI1 | PI12; neuroserpin | serpin family I member 1 |
| TCMBANKGE014254 | SERPINB13 | HSHUR7SEQ; HUR7; PI13; headpin | serpin family B member 13 |
| TCMBANKGE014351 | SERPING1 | C1IN; C1INH; C1NH; HAE1; HAE2 | serpin family G member 1 |
| TCMBANKGE014614 | SERPINH1 | AsTP3; CBP1; CBP2; HSP47; OI10; PIG14; PPROM; RA-A47; SERPINH2; gp46 | serpin family H member 1 |
| TCMBANKGE014798 | SERPINF2 | A2AP; AAP; ALPHA-2-PI; API; PLI | serpin family F member 2 |
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