Compound Summary

  Compound Information

TCMBANKIN058177

药名:	1,2,4-benzenetriol
分子式:	C6H6O3
Smiles:	C1=CC(=C(C=C1O)O)O
成分:	HBIN000643
TCMID_id:	40457
PubChem_id:	10787

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE007098	Fructus Gardeniae	栀子;生山栀			1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness;4.Treatment of febrile diseases with restlessness, jaundice with dark urine, hematuria with difficult painful urination, hemoptysis and epistaxis caused by heat in the blood, inflammation of the eye, boils and sores, external use for sprains and bruises.Fructus Gardeniae (charred): Hemoptysis, epistaxis, hematuria and abnormal uterine bleeding caused by heat in the blood./Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.1. The active components such as crocin, crocetin, genipin, or alcoholic extract protect the liver from carbon tetrachloride and increasing biliary secretion. Oral use of its decoction induce gallbladder contraction.2. Oral or intraperitoneal use of its decoction and alcoholic extract exerts a sustained hypotensive effect in anaesthetized and un-anaesthetized animals.3. Hemostatic.
TCMBANKHE005522/YEM-745/XU-411	Fructus Gardeniae|Gardenia jasminoides(L.)Ellis|Gardenia jasminoides	栀子	栀子	云南民族药物志：第四卷|广东省廉江市石岭镇	1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness/Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.	阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/瑶族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000002	CXCL3	CINC-2b; GRO3; GROg; MIP-2b; MIP2B; SCYB3	C-X-C motif chemokine ligand 3
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000130	TOP2A	TOP2; TP2A	DNA topoisomerase II alpha
TCMBANKGE000196	FAS	ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6	Fas cell surface death receptor
TCMBANKGE000204	CXCL8	GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8	C-X-C motif chemokine ligand 8
TCMBANKGE000223	KEAP1	INrf2; KLHL19	kelch like ECH associated protein 1
TCMBANKGE000241	CASP8	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5	caspase 8
TCMBANKGE000258	EGR1	AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225	early growth response 1
TCMBANKGE000313	JUN	AP-1; AP1; c-Jun; cJUN; p39	Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000396	TOP1	TOPI	DNA topoisomerase I
TCMBANKGE000417	FDXR	ADR; ADXR; ANOA	ferredoxin reductase
TCMBANKGE000505	ATF3	-	activating transcription factor 3
TCMBANKGE000512	BACH1	BACH-1; BTBD24	BTB domain and CNC homolog 1
TCMBANKGE000537	ABCC1	ABC29; ABCC; GS-X; MRP; MRP1	ATP binding cassette subfamily C member 1
TCMBANKGE000538	CYP27A1	CP27; CTX; CYP27	cytochrome P450 family 27 subfamily A member 1
TCMBANKGE000545	CXCL2	CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP2A; SCYB2	C-X-C motif chemokine ligand 2
TCMBANKGE000666	RELB	I-REL; IMD53; IREL; REL-B	RELB proto-oncogene, NF-kB subunit
TCMBANKGE000741	HSPA1B	HSP70-1; HSP70-1B; HSP70-2; HSP70.1; HSP70.2; HSP72; HSPA1; HSX70	heat shock protein family A (Hsp70) member 1B
TCMBANKGE000746	HSPA1A	HEL-S-103; HSP70-1; HSP70-1A; HSP70-2; HSP70.1; HSP70.2; HSP70I; HSP72; HSPA1	heat shock protein family A (Hsp70) member 1A
TCMBANKGE000770	SESN2	HI95; SES2; SEST2	sestrin 2
TCMBANKGE000792	FASLG	ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A	Fas ligand
TCMBANKGE000809	BIRC3	AIP1; API2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49; c-IAP2	baculoviral IAP repeat containing 3
TCMBANKGE000930	ACLY	ACL; ATPCL; CLATP	ATP citrate lyase
TCMBANKGE000941	TXNRD1	GRIM-12; TR; TR1; TRXR1; TXNR	thioredoxin reductase 1
TCMBANKGE000945	HES1	HES-1; HHL; HRY; bHLHb39	hes family bHLH transcription factor 1
TCMBANKGE001005	CTTN	EMS1	cortactin
TCMBANKGE001038	SERPINF1	EPC-1; OI12; OI6; PEDF; PIG35	serpin family F member 1
TCMBANKGE001098	NFKBIA	EDAID2; IKBA; MAD-3; NFKBI	NFKB inhibitor alpha
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001172	HSP90AA1	EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2	heat shock protein 90 alpha family class A member 1
TCMBANKGE001443	RPL15	DBA12; EC45; L15; RPL10; RPLY10; RPYL10	ribosomal protein L15
TCMBANKGE001504	TOP3B	TOP3B1	DNA topoisomerase III beta
TCMBANKGE001597	TOP2B	TOPIIB; top2beta	DNA topoisomerase II beta
TCMBANKGE001643	DDIT4	Dig2; REDD-1; REDD1	DNA damage inducible transcript 4
TCMBANKGE002233	POLR1G	ASE-1; ASE1; CAST; CD3EAP; PAF49; RPA34	RNA polymerase I subunit G
TCMBANKGE002676	SORL1	C11orf32; LR11; LRP9; SORLA; SorLA-1; gp250	sortilin related receptor 1
TCMBANKGE002978	RTN4R	NGR; NOGOR	reticulon 4 receptor
TCMBANKGE003295	GATA2	DCML; IMD21; MONOMAC; NFE1B	GATA binding protein 2
TCMBANKGE003420	GGA1	-	golgi associated, gamma adaptin ear containing, ARF binding protein 1
TCMBANKGE004658	PRUNE1	DRES-17; DRES17; H-PRUNE; HTCD37; NMIHBA; PRUNE	prune exopolyphosphatase 1
TCMBANKGE004677	RILP	PP10141	Rab interacting lysosomal protein
TCMBANKGE004962	STEAP3	AHMIO2; STMP3; TSAP6; dudlin-2; dudulin-2; pHyde	STEAP3 metalloreductase
TCMBANKGE004984	NCK2	GRB4; NCKbeta	NCK adaptor protein 2
TCMBANKGE004985	TTLL4	-	tubulin tyrosine ligase like 4
TCMBANKGE005000	PDE11A	PPNAD2	phosphodiesterase 11A
TCMBANKGE005296	ARL6IP5	DERP11; GTRAP3-18; HSPC127; JWA; PRAF3; Yip6b; addicsin; hp22; jmx	ADP ribosylation factor like GTPase 6 interacting protein 5
TCMBANKGE005626	ZBTB42	LCCS6; ZNF925	zinc finger and BTB domain containing 42
TCMBANKGE005712	DNAJB1	HSPF1; Hdj1; Hsp40; RSPH16B; Sis1	DnaJ heat shock protein family (Hsp40) member B1
TCMBANKGE005976	KLF2	LKLF	Kruppel like factor 2
TCMBANKGE006297	HLA-DPA1	DP(W3); DP(W4); DPA1; HLA-DP1A; HLA-DPB1; HLADP; HLASB; PLT1	major histocompatibility complex, class II, DP alpha 1
TCMBANKGE006480	TNFAIP6	TSG-6; TSG6	TNF alpha induced protein 6
TCMBANKGE006559	GYPA	CD235a; GPA; GPErik; GPSAT; HGpMiV; HGpMiXI; HGpSta(C); MN; MNS; PAS-2	glycophorin A (MNS blood group)
TCMBANKGE006595	TOP1MT	-	DNA topoisomerase I mitochondrial
TCMBANKGE006678	TMEM158	BBP; RIS1; p40BBP	transmembrane protein 158
TCMBANKGE007078	SRSF9	SFRS9; SRp30c	serine and arginine rich splicing factor 9
TCMBANKGE007382	EIF3A	EIF3; EIF3S10; P167; TIF32; eIF3-p170; eIF3-theta; p180; p185	eukaryotic translation initiation factor 3 subunit A
TCMBANKGE007530	HLA-DPB1	DPB1; HLA-DP; HLA-DP1B; HLA-DPB	major histocompatibility complex, class II, DP beta 1
TCMBANKGE007557	NEU3	SIAL3	neuraminidase 3
TCMBANKGE008034	PHLDA1	DT1P1B11; PHRIP; TDAG51	pleckstrin homology like domain family A member 1
TCMBANKGE008042	AREL1	FIEL1; KIAA0317	apoptosis resistant E3 ubiquitin protein ligase 1
TCMBANKGE008068	PRTN3	ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3	proteinase 3
TCMBANKGE008400	BCL3	BCL4; D19S37	BCL3 transcription coactivator
TCMBANKGE008472	RPL5	L5; MSTP030; PPP1R135; uL18	ribosomal protein L5
TCMBANKGE008538	GABPB2	GABPB-2	GA binding protein transcription factor subunit beta 2
TCMBANKGE008799	DGAT2	ARAT; GS1999FULL; HMFN1045	diacylglycerol O-acyltransferase 2
TCMBANKGE008894	NANOS1	EC_Rep1a; NOS-1; NOS1; SPGF12; ZC2HC12A	nanos C2HC-type zinc finger 1
TCMBANKGE008924	CHAC1	-	ChaC glutathione specific gamma-glutamylcyclotransferase 1
TCMBANKGE009435	PPP1R12A	GUBS; M130; MBS; MYPT1	protein phosphatase 1 regulatory subunit 12A
TCMBANKGE009650	ST3GAL3	EIEE15; MRT12; SIAT6; ST3GALII; ST3Gal III; ST3GalIII; ST3N	ST3 beta-galactoside alpha-2,3-sialyltransferase 3
TCMBANKGE009727	ITGA2B	BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93	integrin subunit alpha 2b
TCMBANKGE010087	TFRC	CD71; IMD46; T9; TFR; TFR1; TR; TRFR; p90	transferrin receptor
TCMBANKGE010255	ERO1A	ERO1-L; ERO1-L-alpha; ERO1-alpha; ERO1L; ERO1LA; Ero1alpha	endoplasmic reticulum oxidoreductase 1 alpha
TCMBANKGE010401	PLIN2	ADFP; ADRP	perilipin 2
TCMBANKGE010533	EVA1B	C1orf78; FAM176B	eva-1 homolog B
TCMBANKGE010581	PRDM12	HSAN8; PFM9	PR/SET domain 12
TCMBANKGE011618	EIF3L	EIF3EIP; EIF3S11; EIF3S6IP; HSPC021; HSPC025; MSTP005	eukaryotic translation initiation factor 3 subunit L
TCMBANKGE011702	TNFRSF8	CD30; D1S166E; Ki-1	TNF receptor superfamily member 8
TCMBANKGE011911	RAB22A	-	RAB22A, member RAS oncogene family
TCMBANKGE012112	KCND1	KV4.1	potassium voltage-gated channel subfamily D member 1
TCMBANKGE012246	TLR9	CD289	toll like receptor 9
TCMBANKGE012602	GP1BB	BDPLT1; BS; CD42C; GPIBB; GPIbbeta	glycoprotein Ib platelet subunit beta
TCMBANKGE012711	SH3BP2	3BP-2; 3BP2; CRBM; CRPM; RES4-23	SH3 domain binding protein 2
TCMBANKGE012851	SCIMP	C17orf87; UNQ5783	SLP adaptor and CSK interacting membrane protein
TCMBANKGE013156	PTPN3	PTP-H1; PTPH1	protein tyrosine phosphatase non-receptor type 3
TCMBANKGE013523	ENG	END; HHT1; ORW1	endoglin
TCMBANKGE013925	TOP3A	MGRISCE2; PEOB5; TOP3; ZGRF7	DNA topoisomerase III alpha
TCMBANKGE014133	ADSL	AMPS; ASASE; ASL	adenylosuccinate lyase
TCMBANKGE014451	JARID2	JMJ	jumonji and AT-rich interaction domain containing 2
TCMBANKGE014545	KLHDC7B	-	kelch domain containing 7B
TCMBANKGE014917	NANP	C20orf147; HDHD4; dJ694B14.3	N-acetylneuraminic acid phosphatase