Compound Summary

  Compound Information

TCMBANKIN058178

药名:	Daphnetol
别名:	5-18-03-00211 (Beilstein Handbook Reference); AIDS-026334; HSCI1_000053; NSC 633563; EU-0000106; ZINC00057753; AIDS026334; 2H-1-Benzopyran-2-one, 7,8-dihydroxy- (9CI); KBio1_001904; 7,8-Dihydroxy-2H-1-benzopyran-2-one; KBioGR_001808; 7,8-Dihydroxycoumarin; 7,8-dihydroxy-coumarin; 7,8-dihydroxychromen-2-one; NCGC00015349-01; D5564_SIGMA; Daphnetin; CHEBI:17313; Oprea1_044324; 486-35-1; NSC633563; Spectrum3_000784; KBio3_001708; COUMARIN, 7,8-DIHYDROXY-; 7,8-dihydroxy-2H-chromen-2-one; Lopac0_000330; ST5308908; 2H-1-Benzopyran-2-one, 7,8-dihydroxy-; Spectrum4_001254; BSPBio_002488; C03093; Lopac-D-5564; DivK1c_006960; EINECS 207-632-8; 630764_ALDRICH; BRN 0009372; EU-0100330; SpecPlus_000864; InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12; 7,8-dihydroxy-2-chromenone; 4,8-Dihydroxycoumarin; AC-5538; ZINC21992842; 4,8-Dihydroxy-2H-chromen-2-one; BC216210; 7,8-dihydroxycoumarin; AKOS006290013; AK516453; daphnetin
分子式:	C9H6O4
Smiles:	C1=CC(=C(C2=C1C=CC(=O)O2)O)O
成分:	HBIN022681; HBIN022677
OB_score:	24.225904
CAS_id:	486-35-1
SymMap_id:	SMIT06920; SMIT14897
TCMID_id:	4644
TCMSP_id:	MOL005118
PubChem_id:	5280569

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002206		罗布麻叶
TCMBANKHE004234	Daphne retusa	凹叶瑞香			See Daphne tangutica./See Daphne tangutica.
TCMBANKHE004366	Cicer arietinum	回回豆			To clear heat and resolve toxin./Diabetes mellitus.
TCMBANKHE005729	Semen Euphorbiae	千金子			To cause drastic purgation for treating edema, and eliminate blood stasis for treating masses./Edema, phlegm-rheum, accumulation and distention-fullness, urinary and fecal stoppage, amenorrhea due to blood stasis, intractable impediment, wart.
TCMBANKHE008273/XU-392	Daphne odora	瑞香花|瑞香		湖北省恩施州板桥镇	To quicken blood and relieve pain, resolve toxin and dissipate binds./Swelling pain in throat, headache, toothache, wind-damp pain, mammary welling abscess, swollen hard breast.
TCMBANKHE004391/YNS-175/XU-185	Stellera chamaejasme|Stellera chamaejasme L.	狼毒	绵大戟	云南药材标准：第七册|甘肃省定西市漳县殪虎桥镇	利水消肿、散瘀止血。用于水肿、腹痛气胀、便秘。外用止血。|To expel water and dispel phlegm, break accumulation and kill worms./Edema distention fullness, a ccumulation from phlegm, food accumulation, worm accumulation, pain in heart and abdomen, chronic trachitis, cough, asthma, scab and lichen, hemorrhoids and fistulas, scrofula, bone tuberculosis, epididymis tubercle.
TCMBANKHE006523/XU-115	Flos Genkwa|Daphne genkwa Sieb. et Zucc	芫花		湖北神农架	1. To transform water and stop cough; 2. To resolve phlegm and stop cough; 3. To kill worms/Edema, ascites, hydrothorax, cough with profuse phlegm, chronic bronchitis, malaria, scalp infection, infection of skin, tinea capitis, neurodermatitis, induce abortion, toothache.
TCMBANKHE005628/YEM-121	Fructus Chaenomelis|Chaenomeles speciosa (Sweet) Nakai	木瓜|皱皮木瓜	木瓜	云南民族药物志：第一卷	To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema.	傣族/景颇族/苗族/彝族/藏族
TCMBANKHE000539/YEM-981	Daphne tangutica|Daphne tangutica Maxim.	唐古特瑞香	陕甘瑞香	云南民族药物志：第五卷	To dispel wind and free network vessels, dissipate stasis and relieve pain./Wind-damp impediment pain, numbness in limbs, headache, stomachache, lumbago, knocks and falls.	藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000037

Colitis

disease

Digestive System Diseases

31145641

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000223	KEAP1	INrf2; KLHL19	kelch like ECH associated protein 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000726	CRYZ	-	crystallin zeta
TCMBANKGE001052	NLRP3	AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1	NLR family pyrin domain containing 3
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1