Compound Summary

  Compound Information

TCMBANKIN058196

药名:	4-hydroxy cinnamic acid;trans- p- hydroxy cinnamic acid;trans-p-coumaric acid;p-cumaric acid;4-coumaric acid;P-hydroxy- cinnamic acid;Hydroxycinnamic acid
别名:	4-hydroxycinnamic acid;trans-p-Hydroxycinnamic acid; Trans-p-hydroxy cinnamic acid;AS03322; I01-9546; I01-9648; Para-Coumaric acid; trans-p-Hydroxycinnamate; UNII-IBS9D1EU3J; 4-Hydroxycinamic acid; AK134594; AM20050138; trans-4-Hydroxycinnamic acid; Hydroxycinnamic acid; p-Coumaric acid, primary pharmaceutical reference standard; (E)-3-(4-Hydroxyphenyl)-2-propenoic acid; beta-[4-Hydroxyphenyl]acrylic acid; MP-2217; BP-13278; F2191-0188; IBS9D1EU3J; p-coumaric-acid; STL163567; BG00601173; 2-propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-; 50940-26-6; TR-023948; p-Cumarate; Naringeninic acid; p-Cumaric acid; NCGC00246974-01; (E)-3-(4-Hydroxyphenyl)acrylic acid; CHEBI:36090; AS-12000; N1817; p-Coumaric acid,trans; TL8005115; 501-98-4; bmse010208; bmse000150; TIMTEC-BB SBB007613; DTXSID6064660; p-coumaric acid; NSC-674321; SCHEMBL39106; AKOS 221-47; AC1Q71H0; bmse000591; p-Coumaric acid, trans; MolPort-000-860-894; AE-562/40414679; COUMARIC ACID, TRANS-P-; 4-coumaric acid, (E)-isomer; trans-4-hydroxycinnamate; trans-p-Coumarinic acid; 3-(4-Hydroxyphenyl)-2-propenoate; (E)-3-(4-HYDROXY-PHENYL)-ACRYLIC ACID; LS30305; 3-(4-hydroxyphenyl)acrylic acid; (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid; hydroxycinnamate; 4'-Hydroxycinnamate; SC-25929; trans-p-Hydroxycinnamic acid; (E)-p-Hydroxycinnamic acid; 3-(4-hydroxyphenyl)acrylate; PubChem24323; LS-54111; NGSWKAQJJWESNS-ZZXKWVIFSA-N; trans-4-coumaric acid; trans-p-Cumaric Acid; trans-p-Coumaric acid; AKOS BAR-2479; RTR-023948; RP09062; ZINC39811; 4-10-00-01005 (Beilstein Handbook Reference); 0C1BFF2D-2CF7-4FC1-9F76-3268C2C7F783; LS-54112; C00811; (2E)-3-(4-hydroxyphenyl)acrylic acid; ST2402517; Cinnamic acid, 4-hydroxy-, trans-; BG01501541; 4qem; BDBM4374; HMS1409E10; BRN 2207383; SC-65982; I04-0102; C9H8O3; (E)-3-[4-hydroxyphenyl]-2-propenoic acid; ATTERCOP-CHM AT113965; beta-(4-Hydroxyphenyl)acrylic acid; Para coumaric acid; BCP9001042; MLS001066419; p-Hydroxyphenylacrylic acid; Cinnamic acid, p-hydroxy-; RARECHEM BK HW 0163; 4-Coumaric acid; CS-W020394; TR-017943; p-Coumaric acid, >=98.0% (HPLC); (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid; b-[4-Hydroxyphenyl]acrylate; Q-100560; 7400-08-0; BB_NC-2249; RP17402; BBL012226; AK-26304; W-104438; D0AU0M; p-hydroxycinnamic acid (M4); 2-Propenoic acid, 3-(4-hydroxyphenyl)-, homopolymer; SBB007613; 4-Hydroxycinnamate; ZX-AT011614; Cinnamic acid, p-hydroxy-, (E)-; p-Caumaric acid dehydrogenation homopolymer; SMR000112201; 4f8j; 0-10-00-00297 (Beilstein Handbook Reference); (E)-p-Coumaric acid; 4CN-0926; p-Hydroxycinnamate; (E)-4-hydroxycinnamic acid; 2-Propenoic acid, 3-(4-hydroxyphenyl)-; DB04066; trans-p-Coumaric acid, analytical standard; 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (Z)-; .beta.-[4-Hydroxyphenyl]acrylic acid; p-Coumaricacid; AJ-08911; p-Hydroxy-cinnamic acid; 4-Hydroxy cinnamate; AC1LCUFZ; AKOS000120685; BR-26304; InChI=1/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3; Para coumarate; trans-p-coumarate; 4-Hydroxyphenylpropenoate; P-HYDROXYL CINNAMIC ACID; OTAVA-BB 7020400347; AC-10318; (E)-3-(4-hydroxyphenyl)prop-2-enoic acid; AN-287; LABOTEST-BB LT03329617; p-Hydroxycinnamic acid; MolPort-004-288-351; EINECS 231-000-0; p-Hydroxycinnamic acid, trans; KB-72564; TC-164240; BRN 2207381; 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)-; ST24022578; 4-hydroxy cinnamic acid; NSC 674321; LABOTEST-BB LT00452637; Para-Coumarate; (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid #; b-[4-Hydroxyphenyl]acrylic acid; 4'-hydroxycinnamic acid; beta-[4-Hydroxyphenyl]acrylate; NSC-59260; PubChem8247; 4-Hydroxycinnamic acid; CHEMBL66879; CHEBI:32374; BG01501540; NSC674321; RTR-017943; 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI); NSC59260; 400H080; AX8022446; 3-(4-Hydroxyphenyl)-2-propenoic acid; AC1Q5T95; 3-(4-hydroxyphenyl)prop-2-enoic acid; ST093691; GTPL5787; 4-coumarate; MFCD00004399; NSC 59260;p-hydroxy-cinnamic acid;p- hydroxycinnam icacid; p-hydroxycinnami cacid; p-hydroxy cinnamic acid; p-hydroxycinnamic acid
分子式:	C9H8O3
Smiles:	C1=CC(=CC=C1C=CC(=O)O)O
成分:	HBIN010527;HBIN046814;HBIN046800;HBIN039002;HBIN010301;HBIN039686;HBIN039685;HBIN029711
TCMID_id:	35420;33408;40286;33992;38154;23930;24910;33784;38095;38418;36379;34841;33973;33411;33405;33406
PubChem_id:	637542
DrugBank_id:	DB04066

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001710	Herba Speranskiae tuberculatae	凤仙透骨草			For dispelling wind-dampness and dispersing coldness
TCMBANKHE003943	Herba Cirsii Japonici;Radix Cirsii Japonici;Herba seu Radix Cirsii japonici	大蓟			To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.;Treatment of epistaxis, spitting of blood, hematuria, hematochezia, abnormal uterine bleeding, traumatic bleeding, carbuncles and sores./1. Its decoction can lower blood pressure2. Inhibiting the growth of (a)-streptococcus3. Shortening the bleeding time.4. Anti-inflammatory5. Diuretic.
TCMBANKHE004080	Campsis grandiflora	紫葳			To clear heat and cool blood, transform stasis and dissipate binds, dispel wind and relieve itch./Blood stagnation and menstrual block, dysmenorrhea, concretion and conglomeration, flooding and spotting, wind papule itching due to blood heat, urticari with sore and scab, brandy nose.
TCMBANKHE008733	Tadehagi triquetrum	葫芦茶			To clear heat and resolve toxin, disperse accumulation and disinhibit damp, kill worms./Common cold with fever, swelling pain in throat, nephritis, icterohepatitis, enteritis, bacillary dysentery, vomiting in pregnancy, ancylostomiasis.
TCMBANKHE004946	Herba Hedyotis Diffusae	白花蛇舌草			1. To eliminate heat and toxic material, promote blood circulation and remove blood stasis. 2. To clear dampness-heat./Lung heat cough asthma, swelling pain in throat, intestinal welling abscess, swelling of sores and boils, poisonous snake bite, heat strangury with inhibited pain, edema, dysentery, enteritis, damp-heat jaundice, carcinoma.
TCMBANKHE005005	Rhizoma Curcumae	广西莪术			Treatment of mass in the abdomen, amenorrhea due to blood stasis, distension and pain due to stagnation of undigested food, carcinoma of cervix at early stage./Treatment of mass in the abdomen, amenorrhea due to blood stasis, distension and pain due to stagnation of undigested food, carcinoma of cervix at early stage.
TCMBANKHE005210	Flos Inulae	旋覆花			To relieve cough, eliminate phlegm, promote diuresis, and arrest vomiting./1. Its alcoholic extract is a diuretic in experimental rabbits.2. The decoction inhibits the growth Staphylococcus aureus and pneumococcus in vitro.
TCMBANKHE005549	Styrax	苏合香			1. To open the orifices and clear the mind; 2. To stop pain/Wind stroke with phlegm reversal, sudden clouding collapse, cold pain in chest and abdomen, fright epilepsy, warm disease.
TCMBANKHE005736	Herba Commelie	鸭跖草			1. Clear away heat and toxic materials. 2. Clear away heat and promote diuresis. /Common cold, wind-heat common cold, influenza, noninfectious fever, ardent fever incessant, ascites, edema, hordeolum, swelling pain in throat, scant urine with edema, heat strangury with inhibited pain, swollen welling abscess and toxin of clove.
TCMBANKHE009190	Fructus Mori	桑椹			To nourish n and blood and promote the production of body fluid./Its contains sugar, organic acid , vitamins B1, B2 and C and carotene. Its oleum contains oleic acid and linoleic acid.
TCMBANKHE005929	Radix et Rhizoma Notopterygii	羌活			To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE008626	Cortex Lycii Radicis	地骨皮			To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE006546	Cephalotaxus fortunei	三尖杉			Anticancer./Carcinoma of stomach, carcinoma of rectum, carcinoma of lung, carcinoma of esophagus, lymphatic sarcoma, leukaemia.
TCMBANKHE000631/YEM-135	herba meconpsis integrifoliae|Meconopsis integrifolia(Maxim.) Franch.	绿绒蒿|全缘叶绿绒蒿	全缘叶绿绒蒿	云南民族药物志：第一卷		傈僳族/藏族
TCMBANKHE003868/YEM-171/XU-671	Camptotheca acuminata|Camptotheca acuminata Decne.	喜树	喜树	云南民族药物志：第一卷|云南省红河州屏边县	To clear heat and resolve toxin, dissipate binds and disperse concretion, anticancer./Acute leukemia, chronic leukemia, psoriasis, swollen liver and spleen due to bilharziosis, carcinoma of esophagus, carcinoma of cardia, carcinoma of intestine, carcinoma of liver, carcinoma of stomach, swelling of sores.	阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE006796/YEM-231/XU-530/XU-604	Senecio scandens [Syn. Senecio chinensis]|Senecio scandens Buch.-Ham.ex D.Don|Senecio scandens	千里光	千里光	云南民族药物志：第二卷|云南省昆明市呈贡区梁王山	To clear heat and resolve toxin, eliminate screen and brighten eyes, kill worms and relieve itch./Wind-fire eye, conjunctivitis, eye screen, typhoid fever, acute bacillary dysentery, pneumonia, lobar pneumonia, tonsillitis, appendicitis, bronchitis, enteritis, jaundice, influenza, toxemia, hematosepsis, swelling toxin of welling abscess and boil, dry lichen, damp lichen, erysipelas, eczema, scalds, trichomoniasis.	白族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/佤族/彝族
TCMBANKHE008071/YEM-274	Spora Lygodii|Lygodium japonicum(Thunb.)Sw.	海金沙	海金沙	云南民族药物志：第二卷	To promote diuresis and treat stranguria/Heat strangury, stone strangury, blood strangury, inhibited urination [=dysuria], edema, white turbidity, vaginal discharge, hepatitis, diarrhea, dysentery, common cold with fever, cough and asthma, swelling pain in throat, mouth sore, red eyes with gall, mumps, mammary welling abscess, erysipelas, zoster, burns and scalds, itchy skin, wound swelling from knocks and falls, wind-damp impediment pain, bleeding due to external injury.	阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/彝族/藏族
TCMBANKHE007819/YEM-691	Mangifera indica|Mangifera indica L.	杧果叶|杧果	杧果	云南民族药物志：第四卷	To allay thirst, transform stagnation, relieve itch./Gan accumulation, diabetes mellitus, eczema titillation, wart.	阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000949	UGT2B4	HLUG25; UDPGT2B4; UDPGTH1; UDPGTh-1; UGT2B11	UDP glucuronosyltransferase family 2 member B4
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001069	MPO	-	myeloperoxidase
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001079	CYP1A1	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX	cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001107	NOS3	ECNOS; eNOS	nitric oxide synthase 3
TCMBANKGE002897	UGT1A3	UDPGT; UDPGT 1-3; UGT-1C; UGT1-03; UGT1.3; UGT1A3S; UGT1C	UDP glucuronosyltransferase family 1 member A3
TCMBANKGE003402	UGT3A2	-	UDP glycosyltransferase family 3 member A2
TCMBANKGE004083	SULT1A1	HAST1/HAST2; P-PST; PST; ST1A1; ST1A3; STP; STP1; TSPST1	sulfotransferase family 1A member 1
TCMBANKGE004118	PXDN	ASGD7; COPOA; D2S448; D2S448E; MG50; PRG2; PXN; VPO	peroxidasin
TCMBANKGE004369	ZADH2	PRG-3	zinc binding alcohol dehydrogenase domain containing 2
TCMBANKGE004457	UGT2B17	BMND12; UDPGT2B17	UDP glucuronosyltransferase family 2 member B17
TCMBANKGE004508	UGT3A1	-	UDP glycosyltransferase family 3 member A1
TCMBANKGE004778	UGT2B15	HLUG4; UDPGT 2B8; UDPGT2B15; UDPGTH3; UGT2B8	UDP glucuronosyltransferase family 2 member B15
TCMBANKGE006233	UGT1A9	HLUGP4; LUGP4; UDPGT; UDPGT 1-9; UGT-1I; UGT1-09; UGT1-9; UGT1.9; UGT1A9S; UGT1AI; UGT1I	UDP glucuronosyltransferase family 1 member A9
TCMBANKGE006368	UGT1A1	BILIQTL1; GNT1; HUG-BR1; UDPGT; UDPGT 1-1; UGT1; UGT1A	UDP glucuronosyltransferase family 1 member A1
TCMBANKGE006394	UGT1A7	GNT1; UDPGT; UDPGT 1-7; UGT-1A; UGT-1G; UGT1; UGT1-01; UGT1-07; UGT1.1; UGT1.7; UGT1A; UGT1A1; UGT1G; hUG-BR1	UDP glucuronosyltransferase family 1 member A7
TCMBANKGE006404	UGT1A6	GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT-1A; UGT-1C; UGT-1E; UGT1; UGT1-01; UGT1-03; UGT1-05; UGT1.1; UGT1.3; UGT1.5; UGT1A; UGT1A1; UGT1A3; UGT1A5; UGT1A6S; UGT1C; UGT1E; UGT1F; hUG-BR1	UDP glucuronosyltransferase family 1 member A6
TCMBANKGE006820	UGT8	CGT; UGT4	UDP glycosyltransferase 8
TCMBANKGE007295	UGT2A3	-	UDP glucuronosyltransferase family 2 member A3
TCMBANKGE007846	HAL	HIS; HSTD	histidine ammonia-lyase
TCMBANKGE008362	PTGR2	HEL-S-298; PGR2; ZADH1	prostaglandin reductase 2
TCMBANKGE008742	UGT2B28	-	UDP glucuronosyltransferase family 2 member B28
TCMBANKGE010801	UGT2B10	UDPGT2B10	UDP glucuronosyltransferase family 2 member B10
TCMBANKGE011077	UGT2B11	-	UDP glucuronosyltransferase family 2 member B11
TCMBANKGE011299	UGT2B7	UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTh-2; UGT2B9	UDP glucuronosyltransferase family 2 member B7
TCMBANKGE011699	UGT1A5	UDPGT; UDPGT 1-5; UGT1E	UDP glucuronosyltransferase family 1 member A5
TCMBANKGE012485	PTGR1	LTB4DH; PGR1; ZADH3	prostaglandin reductase 1
TCMBANKGE012749	UGT2A1	UDPGT2A1	UDP glucuronosyltransferase family 2 member A1 complex locus
TCMBANKGE012823	UGT1A8	GNT1; UDPGT; UDPGT 1-8; UGT-1A; UGT-1H; UGT1; UGT1-01; UGT1-08; UGT1.1; UGT1.8; UGT1A; UGT1A1; UGT1A8S; UGT1H; hUG-BR1	UDP glucuronosyltransferase family 1 member A8
TCMBANKGE013930	TYR	ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3	tyrosinase
TCMBANKGE013944	UGT1A4	GNT1; HUG-BR2; UDPGT; UDPGT 1-4; UGT-1A; UGT-1D; UGT1; UGT1-01; UGT1-04; UGT1.1; UGT1.4; UGT1A; UGT1A1; UGT1A4S; UGT1D; hUG-BR1	UDP glucuronosyltransferase family 1 member A4
TCMBANKGE014087	EPX	EPO; EPP; EPX-PEN; EPXD	eosinophil peroxidase
TCMBANKGE014147	UGT1A10	GNT1; UDPGT; UGT-1A; UGT-1J; UGT1; UGT1-01; UGT1-10; UGT1.1; UGT1.10; UGT1A; UGT1A1; UGT1J; hUG-BR1	UDP glucuronosyltransferase family 1 member A10
TCMBANKGE014523	LPO	SPO	lactoperoxidase
TCMBANKGE014572	TPO	MSA; TDH2A; TPX	thyroid peroxidase
TCMBANKGE015090	CYP1A2	CP12; CYPIA2; P3-450; P450(PA)	cytochrome P450 family 1 subfamily A member 2
TCMBANKGE015144	PXDNL	PMR1; PRM1; VPO2	peroxidasin like