Compound Summary


  Compound Information

药名:

phloridzin;Phlorizin

别名:

phloretin 2'-O-glucoside;1-propanone, 1-[2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-; ZINC03875408; C01604; 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one; KBio2_001771; 1-[2-(.beta.-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; KBioSS_001771; KBioGR_002141; Spectrum_001291; 4,6-dihydroxy-2-(beta-D-glucosido)-beta-(p-hydroxyphenyl)propiophenone; 60-81-1; Spectrum4_001651; SPBio_000881; 2'-(beta-D-Glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone; AIDS-009884; KBio2_004339; AIDS009884; 16055-86-0; AI3-19835; KBio2_006907; Spectrum3_001227; SpecPlus_000325; EINECS 200-487-1; 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one; 1-[2,4-dihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]phenyl]-3-(4-hydroxyphenyl)propan-1-one; 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one; phlorizin; Phlorhizin; Phloridzosid; Phlorhizin;Phlorizin; DivK1c_006421; SDCCGMLS-0066626.P001; Phloretin 2'-glucoside; 52276-56-9; KBio1_001365; Phloretin-2'-beta-glucoside; BSPBio_002674; Phloridzin; SBB005924; NCGC00142423-01; KBio3_002174; NSC 2833; Phlorrhizen; 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside; 1-Propanone, 1-(2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-; Spectrum5_000521; 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one; Floridzin; CHEBI:8113; Spectrum2_000701; 112318-65-7; SPECTRUM300547; 2'-(.beta.-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone

分子式:

C21H24O10

Smiles:

C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O

成分:

HBIN039577;HBIN039580

OB_score:

2.884397

CAS_id:

112318-65-7

SymMap_id:

SMIT17191;SMIT04008

TCMID_id:

17156;33365

TCMSP_id:

MOL001623

PubChem_id:

6072


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000174 八角莲
TCMBANKHE005060 Kalmia latifolia 宽叶山月桂
TCMBANKHE007765 覆盆子 Impotence with premature ejaculation, emission, infertility due to uterus cold, frequent urination and enuresis, dizziness and dim vision, premature graying in beard and hair.
TCMBANKHE005586 Fructus Crotonis;Croton macrostachys 巴豆 1. To drain accumulated cold downward; 2. To transform water and reduce edema; 3. To resolve phlegm and benefit throat/Distention fullness and sudden pain in chest and a bdomen, fecal stoppage, diarrhea and dysentery, edema and enlarged abdomen, phlegm-rheum asthma fullness, throat wind, throat impediment, concretion and conglomeration, welling abscess and flat abscess, malign sore and scab lichen.
TCMBANKHE008689 Pieris japonica 日本马醉木 To kill worms./Scab sore.
TCMBANKHE005078/YNS-152/YEM-111 Balanophora involucrata|Balanophora involucrata Hook. f.|Balanophora involucrata Hook.f. 筒鞘蛇菰|蛇菰 鹿仙草 云南药材标准:第一册|云南民族药物志:第一卷 清热止血,用于阳痿,神经功能症,慢性肝炎,胃痛,消化道出血,月经过多|To moisten lung and relieve cough, move qi and fortify stomach, clear heat and disinhibit damp, cool blood and stanch bleeding./Lung heat cough, pain in stomach duct and abdomen, jaundice, swelling pain from hemorrhoids, knocks and falls, hemoptysis, menstrual disorder, flooding and spotting, bleeding due to external injury, dizziness, emission. 白族/傈僳族/纳西族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000130 TOP2A TOP2; TP2A DNA topoisomerase II alpha
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000396 TOP1 TOPI DNA topoisomerase I
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE001504 TOP3B TOP3B1 DNA topoisomerase III beta
TCMBANKGE001597 TOP2B TOPIIB; top2beta DNA topoisomerase II beta
TCMBANKGE003794 SLC5A2 SGLT2 solute carrier family 5 member 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005752 SLC5A10 SGLT-5; SGLT5 solute carrier family 5 member 10
TCMBANKGE006595 TOP1MT - DNA topoisomerase I mitochondrial
TCMBANKGE007615 SLC5A3 BCW2; SMIT; SMIT1; SMIT2 solute carrier family 5 member 3
TCMBANKGE009236 SLC5A1 D22S675; NAGT; SGLT1 solute carrier family 5 member 1
TCMBANKGE010521 SLC5A11 KST1; RKST1; SGLT6; SMIT2 solute carrier family 5 member 11
TCMBANKGE010960 SLC5A4 DJ90G24.4; SAAT1; SGLT3 solute carrier family 5 member 4
TCMBANKGE013424 LCT LAC; LPH; LPH1 lactase
TCMBANKGE013925 TOP3A MGRISCE2; PEOB5; TOP3; ZGRF7 DNA topoisomerase III alpha
TCMBANKGE014679 SLC5A9 SGLT4 solute carrier family 5 member 9