Compound Summary


  Compound Information

药名:

isoflavone

别名:

genistein(1-); 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-olate; isoflavone ; CHEBI:74224; ST5331741; 574-12-9; 3-phenylchromen-4-one; 3-Phenylchromone; 4H-1-Benzopyran-4-one, 3-phenyl- (9CI); 3-phenyl-4H-1-benzopyran-4-one; NSC 135405; C00799; 3-phenyl-4-chromenone; CHEBI:18220; NSC135405; AIDS-002244; Isoflavone (8CI); 3-phenyl-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 3-phenyl-; Isoflavone; AIDS002244; Isoflavon

分子式:

C15H10O2

Smiles:

C1=CC=C(C=C1)C2=COC3=CC=CC=C3C2=O

成分:

HBIN030738; HBIN030737

OB_score:

49.029786

CAS_id:

574-12-9

SymMap_id:

SMIT18541; SMIT12469

TCMID_id:

24167

TCMSP_id:

MOL011593;

PubChem_id:

72304


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000711 焦三仙
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE003520 Semen Glycine Max 黑豆
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003736 银杏叶
TCMBANKHE004934 Trifolium hybridum 杂交车轴草
TCMBANKHE006013 Semen Sojae Praeparata 淡豆豉 To induce diaphoresis, to ease the mind, and to relieve fever./Treatment of chills, fever and headache in colds and influenza, vexation, oppressed feeling in the chest and insomnia.
TCMBANKHE002596/YEM-381 Semen Sojae|Glycine max(L.)Merr. 新豉|大豆 黄豆 云南民族药物志:第二卷 Treatment of chills, fever and headache in colds and influenza, vexation, oppressed feeling in the chest and insomnia./Treatment of chills, fever and headache in colds and influenza, vexation, oppressed feeling in the chest and insomnia. 彝族
TCMBANKHE002228/YEM-381 Semen Sojae Preparatum|Glycine max(L.)Merr. 豆豉|大豆 黄豆 云南民族药物志:第二卷 1. Treatment of wind-cold exterior syndrome. Prepared soybean (Douchi) is used with Chinese green onion (Congbai) in the formula Cong Chi Tang. 2. Treatment of wind-heat exterior syndrome. Prepared soybean (Douchi) is used with Arctium fruit (Niubangzi) and Forsythia fruit (Lianqiao). 3. Treatment of irritability, restlessness and insomnia following febrile disease. Prepared soybean (Douchi) is used with Capejasmine (Zhizi) in the formula Zhizi Chi Tang./1. Treatment of wind-cold exterior syndrome. Prepared soybean (Douchi) is used with Chinese green onion (Congbai) in the formula Cong Chi Tang. 2. Treatment of wind-heat exterior syndrome. Prepared soybean (Douchi) is used with Arctium fruit (Niubangzi) a 彝族
TCMBANKHE002842/YEM-381 Semen Sojae Germinatus|Glycine max(L.)Merr. 大黄豆卷|大豆 黄豆 云南民族药物志:第二卷 彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1