Compound Summary

  Compound Information

TCMBANKIN058381

药名:	4-hydroxy-2-quinolinecarboxylic acid
别名:	kynurenic acid; KYNA
分子式:	C10H7NO3
Smiles:	C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
成分:	HBIN010459
CAS_id:	492-27-3
TCMSP_id:	MOL010768
PubChem_id:	3845

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE005929	Radix et Rhizoma Notopterygii	羌活			To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE004973	Herba Ephedrae	麻黄			To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000212	GRIN1	GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1	glutamate ionotropic receptor NMDA type subunit 1
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001079	CYP1A1	AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX	cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001080	AHR	RP85; bHLHe76	aryl hydrocarbon receptor
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001467	LTA4H	-	leukotriene A4 hydrolase
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE001818	NQO2	DHQV; DIA6; NMOR2; QR2	N-ribosyldihydronicotinamide:quinone reductase 2
TCMBANKGE003424	ACMSD	-	aminocarboxymuconate semialdehyde decarboxylase
TCMBANKGE005653	GRIN2A	EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A	glutamate ionotropic receptor NMDA type subunit 2A
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006466	GRIN2D	EB11; EIEE46; GluN2D; NMDAR2D; NR2D	glutamate ionotropic receptor NMDA type subunit 2D
TCMBANKGE006477	GRIN3B	GluN3B; NR3B	glutamate ionotropic receptor NMDA type subunit 3B
TCMBANKGE008163	GRIN3A	GluN3A; NMDAR-L; NMDAR3A; NR3A	glutamate ionotropic receptor NMDA type subunit 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013281	AADAT	KAT2; KATII; KYAT2	aminoadipate aminotransferase
TCMBANKGE013361	GRIN2C	GluN2C; NMDAR2C; NR2C	glutamate ionotropic receptor NMDA type subunit 2C
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1