Compound Summary


  Compound Information

药名:

Norharman

别名:

244-63-3; BSPBio_002322; ZINC00066039; SMR000058207; KBio3_001542; BRN 0128414; Carbazoline; KBio2_001612; InChI=1/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13; 9H-beta-carboline; AIDS109050; 5-23-08-00220 (Beilstein Handbook Reference); norharman; Norharmane; EINECS 205-959-0; 9H-Pyrido[3,4-B]indole; Prestwick_363; NSC84417; AG-670/31510009; KBio2_006748; .beta.-Carboline; MLS000069651; Spectrum4_001915; Spectrum2_000588; AIDS-109050; Spectrum_001132; 9H-$b-carboline; SMP2_000349; NCIOpen2_001217; KBioSS_001612; 2,9-Diazafluorene; Spectrum5_000630; KBio2_004180; SDCCGMLS-0003278.P003; Carbazoline (VAN); 2-Azacarbazole; CCRIS 6915; ST5307983; Spectrum3_000741; SPBio_000436; NSC 84417; NCGC00021302-03; N6252_SIGMA; KBioGR_002537; WLN: T B656 EN HMJ;beta-carboline

分子式:

C11H8N2

Smiles:

C1=CC=C2C(=C1)C3=C(N2)C=NC=C3

成分:

HBIN037343;HBIN018002

OB_score:

18.884261

CAS_id:

244-63-3

SymMap_id:

SMIT08395

TCMID_id:

15743

TCMSP_id:

MOL006844

PubChem_id:

64961


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004664 Radix Codonopsis pilosulae 党参 To reinforce qi and invigorate the function of the spleen and the lung./Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE005252 枳椇子 Drunkenness, vexation and thirst, vomiting, inhibited urine and stool.
TCMBANKHE005736 Herba Commelie 鸭跖草 1. Clear away heat and toxic materials. 2. Clear away heat and promote diuresis. /Common cold, wind-heat common cold, influenza, noninfectious fever, ardent fever incessant, ascites, edema, hordeolum, swelling pain in throat, scant urine with edema, heat strangury with inhibited pain, swollen welling abscess and toxin of clove.
TCMBANKHE005841 Rhizoma Arisaematis 天南星 To remove damp-phlegm, to dispel wind and arrest convulsions, and to promote the subsidence of induration and swelling./Wind stroke with congesting phlegm, deviated eyes and mouth, hemiplegia, deadlimb, wind-phlegm dizziness, epilepsy, fright wind, tetanus, spasm, neuralgia, cough with profuse phlegm, swollen welling abscess, scrofula, poisonous snake bite, knocks and falls, carcinoma of uterine cervix.
TCMBANKHE005946 Dryopteris austriaca 奥地利鳞毛蕨 To expel worms./Taeniasis.
TCMBANKHE006426 Flos Daturae 洋金花 To relieve asthma and cough, to alleviate pain, and to arrest spasm./Cough and asthma without phlegm, cold pain in heart and Datura stramonium .
TCMBANKHE006919 flos farfarae 款冬花 To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE007230 Rhizoma Pinelliae 半夏 To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium./Cough and asthma with abundant phlegm, vomiting nausea, glomus in chest, dizziness, headache, vexation and agitation in night, goiters with phlegm node, swelling toxin of welling abscess and flat abscess.
TCMBANKHE009133 Radix Codonopsis pilosulae 西党;党参 Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;To reinforce qi and invigorate the function of the spleen and the lung./Treatment of weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools, diabetes caused by internal heat;Spleen-stomach vacuity, reduced food intake and sloppy stool, lassitude in limbs, cough and asthma due to lung vacuity, shortness of breath and spontaneous sweating, qi-blood depletion.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE003831/YEM-100 Polygala tenuifolia|Polygala sibirica L. 远志|西伯利亚远志 苦远志 云南民族药物志:第一卷 To quiet heart and spirit, dispel phlegm and open orifices, resolve toxin and disperse swelling./Pharyngitis, disquieted heart spirit, fright palpitation and insomnia, amnesia, fright epilepsy, cough with profuse phlegm, effusion of back from welling abscess and flat abscess, painful swollen breast. 白族/拉祜族/傈僳族/纳西族/佤族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1