Compound Summary
Compound Information
药名: | chrysazin |
别名: | LTAN;danthron;9,10-Anthracenedione, 1,8-dihydroxy-; KBioGR_001944; ACon1_000135; Spectrum4_001682; NCI60_041443; 1,8-Dihydroxy-9,10-anthracenedione; 1,8-dihydroxyanthra-9,10-quinone; 1,8-Dihydroxyanthrachinon [Czech]; KBio2_002230; Roydan; Istan; InChI=1/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16; Chrysazin; Spectrum_001750; Modane; Usaf nd-59; Dantron; NSC 38626; AIDS-001375; EU-0099935; Danivac; EINECS 204-173-5; 1,8-Dihydroxy-9,10-anthraquinone; 117-10-2; Dionone; Laxanorm; CCRIS 3529; Dioxyanthrachinonum; KBio2_007366; Dorbanex; AI3-38117; NCGC00091367-02; NSC646568; Altan; NCGC00091367-01; Anthraquinone, 1,8-dihydroxy-; 1,8-Dihydroxyanthracene-9,10-dione; Laxanthreen; KBioSS_002230; MEGxp0_001693; NSC 646568; 1,8-Dihydroxyanthraquinone; C10312; component of Modane; Danthron [BAN]; D108103_ALDRICH; Laxipur; Duolax; CHEBI:3682; BSPBio_002259; ZINC03860369; ST5330603; AIDS001375; Dantrona [INN-Spanish]; Dorbane; KBio3_001479; Zwitsalax; NSC7210; SPECTRUM211468; Scatron D; SMR000059018; Spectrum5_000324; Chrysazine; NSC38626; Danthron; Spectrum3_000650; Pastomin; Dantrone [INN-French]; KBio1_000284; MLS000069608; 1,8-Dihydroxyanthrachinon; component of Doxidan; IDI1_000284; Laxipurin; Antrapurol; DivK1c_000284; Diaquone; Bancon; Neokutin S; Dantronum [INN-Latin]; NCIMech_000114; Spectrum2_000603; 343235-40-5; Istizin; 32073-07-7; component of Doxan; SPBio_000506; KBio2_004798; component of Dorbantyl; 1,8-Dihydroanthraquinone; NINDS_000284; WLN: L C666 BV IVJ DQ NQ; 1,4,5,8-Tetroxyantraquinone; Prugol;danthron; Chrysazine; Danthron; CAS-117-10-2; Z4XE6IBF3V; NCGC00091367-05; 9,10-Anthracenedione, 1,8-dihydroxy-; KBioGR_001944; ACon1_000135; 3nsq; Spectrum4_001682; NCI60_041443; 1,8-Dihydroxy-9,10-anthracenedione; 1,8-bis(oxidanyl)anthracene-9,10-dione; Danthron [USP]; 1,8-Dihydroxyanthrachinon [Czech]; KBio2_002230; Roydan; DSSTox_CID_328; Istan; BBL013161; InChI=1/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16; dihydroxyanthraquino ne; 1,8-Dihydroxyanthraquinone, Vetec(TM) reagent grade, 96%; Chrysazin; Spectrum_001750; Modane; Usaf nd-59; HMS2091A09; Dantron; NSC 38626; 9, 1,8-dihydroxy-; Dantron, INN; NSC755828; SBI-0051330.P003; EU-0099935; Dantron [INN]; CCG-35470; DB04816; Danivac; HMS3715F08; D0J0EL; ST50330603; NCGC00091367-06; UNII-Z4XE6IBF3V; EINECS 204-173-5; Dantron (Chrysazin; 8,9-DIHYDROXYANTHRACENE-1,10-DIONE; 1,8-Dihydroxy-9,10-anthraquinone; danthro-lax; HSDB 7764; Dionone; 117-10-2; Laxanorm; CCRIS 3529; NSC-646568; Criasazin; Dioxyanthrachinonum; KBio2_007366; RTR-003068; Dorbanex; ANW-17004; SBB057973; AI3-38117; NCGC00258539-01; dianthon; Danthron (1,8-Dihydroxyanthracene-9,10-dione); STK238373; HMS500O06; 8,9-dihydroxy-1,10-anthraquinone; NSC646568; ZX-AT013456; NCGC00091367-02; Altan; 1,8-dioxyanthraquinone; NCGC00091367-01; Anthraquinone, 1,8-dihydroxy-; Laxanthreen; 1,8-Dihydroxyanthracene-9,10-dione; SR-01000721864-2; AB1006759; I14-16739; KBioSS_002230; 1,8-Dihydroxyanthra-9,10-quinone #; MEGxp0_001693; KS-00000W95; NSC 646568; 1,8-Dihydroxyanthraquinone; MolPort-000-564-798; C10312; AC1L1EU5; component of Modane; Danthron [BAN]; Laxipur; Duolax; DTXSID9020328; Laxapur; LTAN; 1,8-Dihydroxy-9,10-anthracenedione, 9CI; MFCD00001211; DSSTox_GSID_20328; CHEBI:3682; ZINC3860369; Danthron, BAN; BRD-K10065684-001-03-3; BSPBio_002259; danthrone; OR61434; NCGC00091367-04; CS-4392; LS-587; BG01537787; ZX-AS004388; SR-01000721864; s4561; NSC-7210; Dantrona [INN-Spanish]; FT-0624445; Dorbane; 1,8-Dihydroxyanthraquinone, 96%; KBio3_001479; Zwitsalax; CHEMBL53418; CTK3J0719; Tox21_111122; ARONIS23892; KSC490O1T; NSC7210; SPECTRUM211468; Scatron D; ACMC-20mzuc; SMR000059018; 140861-59-2; Spectrum5_000324; Dantrona; BG00609013; D07107; BDBM11316; AB00051961_09; Chrysazine; NSC38626; Spectrum3_000650; Pastomin; Dantrone [INN-French]; Dorbanex (Salt/Mix); KBio1_000284; MLS000069608; BRD-K10065684-001-02-5; CHRYSAZIN, PRACT; Dantronum; NSC-755828; 1,8-Dihydroxyanthrachinon; 1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione; Tox21_200986; Anthraquinone-related compound; Pilules Vinchy N.F. (TN); component of Doxidan; IDI1_000284; D0563; DSSTox_RID_75516; QBPFLULOKWLNNW-UHFFFAOYSA-N; Anthraquinone,8-dihydroxy-; Laxipurin; MCULE-5800615690; 1,8-Dihydroxyanthracene-9,10-dione (Danthron); A803710; Antrapurol; DivK1c_000284; HS-1003; Diaquone; Bancon; CTK0F1106; HY-B0923; AN-43229; 1,8-dihydroxy-anthraquinone; Dorbantyl; 1,8-Dihydroxyanthra-9,10-quinone; Dorbantyl (Salt/Mix); Neokutin S; Dantronum [INN-Latin]; AK208660; NCIMech_000114; TR-003068; Pharmakon1600-00211468; Spectrum2_000603; 343235-40-5; NCGC00091367-07; SCHEMBL83688; Istizin; SPBio_000506; component of Doxan; NSC-38626; 1,8 Dihydroxy Anthraquinone; 32073-07-7; Dantron (INN); W-108572; KBio2_004798; NCGC00091367-03; component of Dorbantyl; 1,8-Dihydroanthraquinone; R229; Dantrone; NINDS_000284; AKOS001583216; WLN: L C666 BV IVJ DQ NQ; 1,4,5,8-Tetroxyantraquinone; BB_NC-0487; C14H8O4; Tox21_111122_1; RP28420; Prugol; Istizine; BBC/171; 1,10-Anthracenedione, 8,9-dihydroxy- |
分子式: | C14H8O4 |
Smiles: | C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3O |
成分: | HBIN020444;HBIN022668;HBIN033615 |
OB_score: | 343235-40-5 |
CAS_id: | 343235-40-5 |
SymMap_id: | SMIT14657;SMIT08088 |
TCMID_id: | 3599 |
TCMSP_id: | MOL006478 |
PubChem_id: | 2950 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE003373 | Exocarpium Citri grandis | 化橘红 | To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking. | |||
| TCMBANKHE003389 | Cinchona ledgeriana | To interrupt malaria and abate fever, resolve liquor and arouse spleen./Malaria, externally contracted ardent fever, drunkenness. | ||||
| TCMBANKHE004160 | Semen Cassiae;Semen Sene | 决明子 | To remove heat from the liver, to improve eyesight, and to relax bowels./See Cassia obtusifolia. | |||
| TCMBANKHE004797 | Rhamnus purshiana | 波希鼠李 | ||||
| TCMBANKHE005190 | Rhamnus crenata | 黎辣根 | To clear heat and resolve toxin, kill worms and disinhibit damp./Scab sore, intractable lichen, eczema, urticaria, tinea capitis, knocks and falls. | |||
| TCMBANKHE005401 | Rumex crispus | 牛耳大黄 | To clear heat and resolve toxin, cool blood and stanch bleeding, free stool and kill worms./Acute hepatitis, chronic hepatitis, enteritis, dysentery, chronic trachitis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, heat bind constipation, swelling toxin of welling abscess and flat abscess, scab and lichen, bald sores. | |||
| TCMBANKHE008555 | Polygonum multiflorum | 何首乌 | To lower cholesterol, enrich yin and nourish blood, moisten intestines and free stool, interrupt malaria, dispel wind, resolve toxin./Backache, neurasthenia, hyperlipemia, neurosis, insomnia, dizziness due to anemia, palpitation, limp aching lumbus and knees due to liver kidney yin vacuity, premature graying in beard and hair, tinnitus, emission, intestinal dry and constipation, enduring malaria, wind papule itching, sore and welling abscess, scrofula, hemorrhoids. | |||
| TCMBANKHE006959/YNS-135/YEM-14 | Semen Cassiae;Semen Sene|Cassia tora Linn.|Cassia tora L. | 决明子;草决明|决明 | 决明根|草决明 | 云南药材标准：第三册|云南民族药物志：第一卷 | 安神补脑，清肝明目，理气止痛。主治失眠多梦，入睡易惊，腹内痉挛剧痛，腹部包块，黄疸，疟疾。|To remove heat from the liver, to improve eyesight, and to relax bowels.Treatment of inflammation in the eye with pain, photophobia and lacrimination, headache, dizziness, blurred vision and constipation./See Cassia obtusifolia.1. Oral adminstration of the hearbal powder can inhibit the rising of serum cholesterol and formation of atherosclerosis in rabbits.2. Its tincture and infusion can inhibit the myocardium of toad in vitro, and contract th eblood vessels of lower limbs.3. Its infusion can lower the blood pressure in dogs, cats and rabbits.4. Chrysophanol, one of the active components, is a laxative.5. Bacteriostatic. | 傣族/基诺族/拉祜族/傈僳族/苗族/佤族/彝族/藏族 |
| TCMBANKHE005278/YEM-158 | Cassia occidentalis|Cassia occidentalis L. | 望江南 | 望江南 | 云南民族药物志：第一卷 | To clear lung, clear liver, calm asthma, disinhibit urine, free stool, resolve toxin and disperse swelling, lower blood pressure./Cough and asthma, hypertension, headache and red eyes, dribbling urination, constipation, swelling toxin of welling abscess and sore, snake or insect bites. | 阿昌族/傣族/德昂族/景颇族/傈僳族 |
| TCMBANKHE004455/YEM-744/XU-850 | Rheum palmatum|Rheum palmatum L. | 掌叶大黄 | 掌叶大黄 | 云南民族药物志：第四卷|西藏昌都地区芒康县 | See Rheum officinale./See Rheum officinale. | 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE004961/YNS-90/YEM-971 | Cassia siamea|Cassia siamea Lam. | 铁刀木 | 黑心树 | 云南药材标准：第三册|云南民族药物志：第五卷 | 清火解毒，杀虫止痒，除风止痛，通血消肿。用于皮肤疔疮疥癣、风疹、麻疹、水痘、湿疹、痱子及皮肤瘙痒；风湿病肢体关节肿胀疼痛；跌打损伤。 | 阿昌族/傣族/德昂族/景颇族/傈僳族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000196 | FAS | ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 | Fas cell surface death receptor |
| TCMBANKGE000241 | CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | caspase 8 |
| TCMBANKGE000288 | ATF6 | ACHM7; ATF6A | activating transcription factor 6 |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE000384 | AIFM1 | AIF; AUNX1; CMT2D; CMTX4; COWCK; COXPD6; DFNX5; NADMR; NAMSD; PDCD8; SEMDHL | apoptosis inducing factor mitochondria associated 1 |
| TCMBANKGE000515 | DIABLO | DFNA64; SMAC | diablo IAP-binding mitochondrial protein |
| TCMBANKGE000715 | BID | FP497 | BH3 interacting domain death agonist |
| TCMBANKGE000792 | FASLG | ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A | Fas ligand |
| TCMBANKGE000809 | BIRC3 | AIP1; API2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49; c-IAP2 | baculoviral IAP repeat containing 3 |
| TCMBANKGE000810 | BIRC2 | API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1 | baculoviral IAP repeat containing 2 |
| TCMBANKGE001011 | TNFSF10 | APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL | TNF superfamily member 10 |
| TCMBANKGE001013 | BIRC5 | API4; EPR-1 | baculoviral IAP repeat containing 5 |
| TCMBANKGE001076 | SOD2 | GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD | superoxide dismutase 2 |
| TCMBANKGE001077 | HSPA5 | BIP; GRP78; HEL-S-89n; MIF2 | heat shock protein family A (Hsp70) member 5 |
| TCMBANKGE001131 | CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | caspase 9 |
| TCMBANKGE001132 | BAX | BCL2L4 | BCL2 associated X, apoptosis regulator |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE001165 | XIAP | API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3 | X-linked inhibitor of apoptosis |
| TCMBANKGE001166 | BCL2 | Bcl-2; PPP1R50 | BCL2 apoptosis regulator |
| TCMBANKGE001169 | BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | BCL2 like 1 |
| TCMBANKGE001205 | DDIT3 | AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 | DNA damage inducible transcript 3 |
| TCMBANKGE003269 | ENDOG | - | endonuclease G |
| TCMBANKGE008921 | RXRA | NR2B1 | retinoid X receptor alpha |
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