Compound Summary
Compound Information
药名: | Sennidin C |
别名: | N2676; Sennoside C; sennidin c; C16797; UQ166P8802; MolPort-023-220-757; [9,9'-Bianthracene]-2-carboxylicacid, 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-,(9R,9'R)-rel-; BG01195722; (9R,9'R)-5,5'-Bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-9,9'-bianthracene-2-carboxylic acid; CHEBI:80734; UNII-UQ166P8802; C42H40O19; (9,9'-Bianthracene)-2-carboxylic acid, 5,5'-bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-, (R*,R*)-; (9R,9'R)-4,4'-DIHYDROXY-2'-(HYDROXYMETHYL)-10,10'-DIOXO-5,5'-BIS({[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY})-9H,9'H-[9,9'-BIANTHRACENE]-2-CARBOXYLIC ACID; 37271-16-2; AK166906; 271S162; X1229; ZINC169722601; BG01794143; Sennoside D; AKOS025287037; Sennoside-C; Q-100439;N2676; C16797; UQ166P8802; MolPort-023-220-757; [9,9'-Bianthracene]-2-carboxylicacid, 5,5'-bis(b-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-,(9R,9'R)-rel-; BG01195722; (9R,9'R)-5,5'-Bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-9,9'-bianthracene-2-carboxylic acid; CHEBI:80734; UNII-UQ166P8802; C42H40O19; (9,9'-Bianthracene)-2-carboxylic acid, 5,5'-bis(beta-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-, (R*,R*)-; sennoside c; (9R,9'R)-4,4'-DIHYDROXY-2'-(HYDROXYMETHYL)-10,10'-DIOXO-5,5'-BIS({[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY})-9H,9'H-[9,9'-BIANTHRACENE]-2-CARBOXYLIC ACID; 37271-16-2; AK166906; 271S162; X1229; ZINC169722601; BG01794143; Sennoside D; AKOS025287037; Sennoside-C; Q-100439;Sennoside C |
分子式: | C42H40O19 |
Smiles: | C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)CO |
成分: | HBIN043751 |
OB_score: | 1.277912;3.993999 |
CAS_id: | 37271-16-2 |
SymMap_id: | SMIT04548;SMIT17677;SMIT04550;SMIT17679 |
TCMID_id: | 19733;19736 |
TCMSP_id: | MOL002272;MOL002275 |
PubChem_id: | 46173829 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE001849 | 倒扣草 | |||||
| TCMBANKHE003426 | Fructus Leonuri | 茺蔚子 | To activate blood circulation and regulate menstruation, to subdue hyperactivity of the liver, and to clear the eye of opacity./Treatment of menstrual disorders, amenorrhea, hysmenorrhea, inflammation of the eye with formation of corneal opacity, dizziness and headache. | |||
| TCMBANKHE003911 | Folium Sene | 番泻叶 | To purge feces downward/Heat bind and accumulation, constipation w ith abdominal pain, edema distention fullness. | |||
| TCMBANKHE006313 | Radix et Rhizoma Rhei | 大黄 | To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds. | |||
| TCMBANKHE005748 | Rheum tanguticum | 唐古特大黄 | See Rheum officinale./See Rheum officinale. | |||
| TCMBANKHE008745 | Cassia acutifolia | 尖叶番泻叶 | See Cassia angustifolia ./See Cassia angustifolia . | |||
| TCMBANKHE006576/YEM-61/XU-569 | Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella | 诃子|微毛诃子 | 诃子 | 云南民族药物志：第一卷|云南省临沧市永德县 | To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain. | 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族 |
| TCMBANKHE004574/YEM-665 | Poria|Poria cocos(Schw.)Wolf | 茯苓 | 茯苓 | 云南民族药物志：第四卷 | To cause diuresis, to invigorate the spleen function, and to calm the mind./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea. | 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族 |
| TCMBANKHE007344/YEM-665 | Poria; Sclerotium Poriae Cocos; Sclerotium Poriae Cocos|Poria cocos(Schw.)Wolf | 茯苓; 云苓|茯苓 | 茯苓 | 云南民族药物志：第四卷 | To cause diuresis, to invigorate the spleen function, and to calm the mind.; Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.; 1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective. | 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族 |
| TCMBANKHE007363/YEM-744/XU-850 | Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum | 大黄; 生锦纹; 生军|掌叶大黄 | 掌叶大黄 | 云南民族药物志：第四卷|西藏昌都地区芒康县 | To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect. | 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE004455/YEM-744/XU-850 | Rheum palmatum|Rheum palmatum L. | 掌叶大黄 | 掌叶大黄 | 云南民族药物志：第四卷|西藏昌都地区芒康县 | See Rheum officinale./See Rheum officinale. | 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
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