Compound Summary

  Compound Information

TCMBANKIN058436

药名:	2, 4-dihydroxy pyrimidine
别名:	NSC3970; C00106; 16908-84-2; U3879_SIGMA; 2,4-Pyrimidinediol; 2-hydroxy-4(3H)-pyrimidinone; 66-22-8; Pirod; 144104-68-7; SQ 7726; Uracil-2-14C; 2,4-Pyrimidinedione; 4433-21-0; D00027; 24897-50-5; U0750_SIGMA; AI3-25470; 766-19-8; U1128_SIGMA; SQ 8493; ST5165192; SQ 6201; 2-hydroxy-4(1H)-pyrimidinone; 2,4-Dioxopyrimidine; 1H-pyrimidine-2,4-dione; Urazil; Pyrod; EINECS 200-621-9; Hybar X; Uracil (JAN/USAN); CHEBI:17568; 6-(3,5-Dimethylbenzyl)-5-ethyl-1-[4-(13-ethyl-17-hydroxy-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylethynyl)benzyloxymethyl]uracil; Uracil-5-d; NCIMech_000782; AC-907/30002021; 2,4-Dihydroxypyrimidine; 42910-77-0; NSC 3970; NSC29742; ZINC00895045; STK301734; AIDS009895; Uracil (8CI); URACIL; Uracil [USAN]; 6-[(3,5-dimethylphenyl)methyl]-5-ethyl-1-[[4-[2-(13-ethyl-17-hydroxy-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl)ethynyl]phenyl]methoxymethyl]pyrimidine-2,4-dione; pyrimidine-2,4(1H,3H)-dione; 4433-24-3; 2,4-(1H,3H)-pyrimidinedione (9CI); CCRIS 3077; RU 12709; Ura; 2,4(1H,3H)-Pyrimidinedione; BMS 205603-01; InChI=1/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8; 2,4(1H,3H)-Pyrimidinedione (9CI); NCI60_003718; 4-hydroxy-2(1H)-pyrimidinone; 2,4(1H,3H)-Pyrimidinedione, labeled with tritium; AIDS-009895
分子式:	C4H4N2O2
Smiles:	C1=CNC(=O)NC1=O
成分:	HBIN004336;HBIN047561
OB_score:	42.525556
CAS_id:	66-22-8
SymMap_id:	SMIT00119
TCMID_id:	42855;22221
TCMSP_id:	MOL001744
PubChem_id:	1174

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000232		川射干
TCMBANKHE001282		瓦松
TCMBANKHE002173	Stigma Croci	西红花			To activate blood circulation and eliminate blood stasis, to remove heat from blood and counteract toxicity, and to calm the nerves./Treatment of amenrrhea with abdominal mass formation, blood stasis after childbirth, eruptions in infectious diseases, emotional dejection, mania.
TCMBANKHE002665		乌头附子尖
TCMBANKHE002732		蚕沙			1. Treatment of damp-heat obstruction syndrome. Silkworm excrement (Cansha) is used with Tetrandra root (Fangji), Coix seed (Yiyiren) and Talc (Huashi) in the formula Xuanbi Tang .2. Eczema. The decoction of the herb is used for external washing. 3. Treat
TCMBANKHE003690		草乌头
TCMBANKHE003775	Radix Aconiti	川乌			To relieve rheumatic conditions and alleviate pain by warming the channels./Treatment of joint pain in rheumatic or rheumatoid arthritis, epigastric pain with cold sensation, or abdominal colic due to cold, also used as an analgesic in anaesthesis.
TCMBANKHE004022	Cordyceps	冬虫夏草			To tonify the lung and the kidney, arrest bleeding, and dispel phlegm./Impotence and emission, neurasthenia, backache, aching in lumbus and knees, enduring cough and vacuity asthma, taxation damage hemoptysis.
TCMBANKHE004258	Radix Angelicae sinensis	当归根			To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE004561	Crocus sativus	臧红花			To quicken blood and transform stasis, dissipate depression and open binds./Anxiety and depression, glomus and oppression in chest and diaphragm, blood ejection, cold damage mania, fright palpitation, amenorrhea, postpartum blood stasis abdominal pain, painful swelling from knocks and falls.
TCMBANKHE004603	Chrysanthemum indicum	野菊			To clear heat and resolve toxin./Common cold, trachitis, hepatitis, hypertension, dysentery, swollen welling abscess, clove sore, red eyes and distending pain, scrofula, eczema.
TCMBANKHE008961	Cordyceps militaris cv	人工蛹虫草			To supplement lung and boost kidney./Tuberculosis, phlegm containing blood, night sweating, blood vaculty, lumbago.
TCMBANKHE005269	Flos Chrysanthemi Indici	野菊花			To remove toxic heat./Hypertension, headache and dizziness, insomnia, common cold, influenza, meningitis, swollen welling abscess and clove sores, red eyes with gall.
TCMBANKHE005359	Bulbus Fritillariae Cirrhosae	川贝母			To remove heat, moisten the lung, resolve phlegm and relieve cough./Lung heat cough, dry cough, chronic bronchitis, infection of upper respiratory tract, tuberculosis, gastric ulcer, duodenal ulcer, yin vacuity taxation cough, cough with phlegm and blood.
TCMBANKHE005368	Pinellia pedatisecta	掌叶半夏			See Arisaema consanguineum./See Arisaema consanguineum.
TCMBANKHE007536		天雄
TCMBANKHE007537		侧子
TCMBANKHE005880	Trogopterus xanthipes, Pteromys volans	五灵脂			To quicken blood and relieve pain, transform stasis and stanch bleeding, disperse accumulation and resolve toxin./Amenorrhea, postpartum blood stasis abdominal pain, flooding, profuse menstruation, incessant red and white vaginal discharge, snake bite, scorpion sting, centipede bite.
TCMBANKHE005929	Radix et Rhizoma Notopterygii	羌活			To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE005954	Radix Pulsatillae	白头翁			1. To clear heat and release toxins; 2. To cool the blood and stop dysentery/Amebic dysentery, nosebleed, flooding and spotting, bleeding from hemorrhoids, cold-heat warm malaria, vaginal discharge, pudendal itch, eczema, scrofula, welling abscess, painful red eyes, neurodermatitis.
TCMBANKHE006054	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE006061	Fructus Evodiae	吴茱萸			1. To dispel cold and stop pain; 2. To pacify the liver and direct rebellious qi downward; 3. To stop vomiting/Dysentery, cold pain in stomach duct and abdomen, reverting yin headache, mounting qi , dysmenorrhea, beriberi with edema, hyperchlorhydria, cold-damp diarrhea.
TCMBANKHE007230	Rhizoma Pinelliae	半夏			To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium./Cough and asthma with abundant phlegm, vomiting nausea, glomus in chest, dizziness, headache, vexation and agitation in night, goiters with phlegm node, swelling toxin of welling abscess and flat abscess.
TCMBANKHE008629	pollen typhae	蒲黄			To arrest bleeding, to remove blood stasis, and to relieve dysuria./Hyperlipemia, angina pectoris, exudative eczema, bleeding, hemoptysis, spontaneous external bleeding, blood ejection, hematochezia, hematuria, flooding and spotting, bleeding due to external injury, pain in heart and abdomen, dysmenorrhea, postpartum bleeding, postpartum abdominal pain, blood strangury with inhibited pain.
TCMBANKHE007928		白药子			Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE008131	Herba Abri	鸡骨草			To remove toxic heat, and to relieve the depressed liver and alleviate pain./Icterohepatitis, stomachache, wind-damp bone pain, stasis pain from knocks and falls, mammary welling abscess.
TCMBANKHE006919	flos farfarae	款冬花			To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE008901	Radix Pseudostellariae	太子参			To replenish qi and invigorate the spleen function, and topromote fluid secretion and moisten the lung./Treatment of hypofunction of the spleen with lassitude and anorexia, debility and deficiency of qi and yin marked by spontaneous sweating and thirst during convalescence dry cough due to dryness of the lung.
TCMBANKHE007176	Fagopyrum tataricum	苦荞麦
TCMBANKHE008104	Radix chuanxiong;Rhizoma Chuanxiong	川芎			1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE007433	Petasites japonicus	蜂斗菜			To clear heat and resolve toxin, dispel stasis and disperse swelling./Swelling pain in throat, swollen welling abscess and toxin of clove, poisonous snake bite, knocks and falls.
TCMBANKHE007762/XU-465	Laggera alata|Laggera alata (D. Don) Sch.-Bip. ex Oliv.	六棱菊|六枝菊			To dispel wind, eliminate damp, transform stagnation, dissipate stasis, disperse swelling, resolve toxin./Common cold with cough, generalized pain, diarrhea, painful joints due to rheumatalgia, menstrual block, knocks and falls, welling abscess and clove sore, scrofula, damp toxin with pruritus.
TCMBANKHE007579	Sargassum	海藻			To soften indurated mass, to eliminate phlegm and dissipate modulation, and to induce diuresis./1. Prevent and treat hypothyroidism caused by deficiency of iodine.2. Its aqueous infusion can lower blood pressure and inhibit the growth of trichophyton.3. Causing atrophy of mammary gland and decreasing milk secretion.
TCMBANKHE006668/YEM-19	Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng.	白木香	沉香	云南民族药物志：第一卷	See Aquilaria agallocha./See Aquilaria agallocha .	阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005671/YEM-254	Radix Dichroae|Dichroa febrifuga Lour.	常山	常山	云南民族药物志：第二卷	To expel phlegm and relieve malaria/Malaria, scrofula.	阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/苗族/佤族/瑶族/彝族
TCMBANKHE005199/YEM-416/XU-321	Fructus Xanthii sibirici|Xanthium sibiricum Patrin ex Widder|Xanthium sibiricum	苍耳子|苍耳	苍耳子	云南民族药物志：第二卷|贵州省毕节市赫章县	To dispel wind and damp, and to relieve nasal obstruction./1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice.	阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005333/YEM-568	Fagopyrum esculentum|Fagopyrum esculentum Moench	荞麦	甜荞	云南民族药物志：第三卷	To fortify spleen and disperse accumulation, precipitate qi and loosen intestines, resolve toxin and close sores./Gastrointestinal accumulation, diarrhea, dysentery, intestine gripping sand, white turbidity, vaginal discharge, spontaneous sweating, night sweating, zoster, erysipelas, effusion of back from welling abscess and flat abscess, scrofula, burns and scalds.	哈尼族/佤族/彝族
TCMBANKHE007564/YEM-928	Aconitum carmichaeli Debx.	漏篮子|乌头	乌头	云南民族药物志：第五卷		阿昌族/布依族/傣族/德昂族/回族/景颇族/傈僳族/苗族/水族/彝族
TCMBANKHE003980/YEM-928	Aconitum carmichaeli|Aconitum carmichaeli Debx.	乌头	乌头	云南民族药物志：第五卷	To dispel wind and eliminate damp, warm channels, dissipate cold and relieve pain./Wind-cold-damp impediment, pain in joints, numbness in limbs, hemiplegia, head wind headache, cold pain in heart and abdomen, cold mounting with pain, stasis pain from knocks and falls, swelling toxin of flat abscess.	阿昌族/布依族/傣族/德昂族/回族/景颇族/傈僳族/苗族/水族/彝族
TCMBANKHE003869/YEM-999/XU-341	Folium Isatidis|Isatis indigotica Fort.|Isatis indigotica	板蓝根（大青叶）|菘蓝	板蓝根	云南民族药物志：第五卷|山东省菏泽市	To clear heat and toxic materials, cool blood and eliminate eruption./Acute parotitis, encephalitis, hepatitis, lung abscess, acute gastroenteritis, infection of upper respiratory tract, warm evil in construction, ardent fever with clouded spirit, macular eruption and papules, jaundice, heat dysentery, epidemic parotitis, throat impediment, erysipelas, swollen welling abscess.	回族/彝族
TCMBANKHE005203/YEM-999/XU-341	Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica	板蓝根|菘蓝	板蓝根	云南民族药物志：第五卷|山东省菏泽市	To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess.	回族/彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述