Compound Summary


  Compound Information

药名:

(?)-cubebin

别名:

18423-69-3; (-)-Cubebin; AI3-62265; (3R,4R)-3,4-BIS(2H-1,3-BENZODIOXOL-5-YLMETHYL)OXOLAN-2-OL; SCHEMBL12857446; BG01069891; 1242843-00-0; 2-Furanol, 3,4-bis(1,3-benzodioxol-5-ylmethyl)tetrahydro-; Tetrahydro-3,4-dipiperonylfuran-2-ol; (2S,3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)tetrahydrofuran-2-ol; Cubebine; AKOS000276832; 2-Furanol, 3,4-bis(1,3-benzodioxol-5-ylmethyl)tetrahydro-, (2S,3R,4R)-; (2S,3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)oxolan-2-ol; rac-Cubebin; AIDS-002469; (2S,3R,4R)-3,4-bis(1,3-benzodioxol-5-ylmethyl)-2-tetrahydrofuranol; .beta.-Cubebin; cubebin; C10549; CHEMBL3752996; EINECS 242-300-6; AIDS002469; 2-Furanol, tetrahydro-3,4-dipiperonyl-; Cubebin; (- )-cubebin

分子式:

C20H20O6

Smiles:

C1C(C(C(O1)O)CC2=CC3=C(C=C2)OCO3)CC4=CC5=C(C=C4)OCO5

成分:

HBIN021825;HBIN021824;HBIN021823

OB_score:

57.128129

CAS_id:

18423-69-3

SymMap_id:

SMIT13874;SMIT14807

TCMID_id:

4306;39909;4305

TCMSP_id:

MOL013187

PubChem_id:

117443


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE004172 Radix Bupleuri 柴胡 To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE004524 Herba Polygoni Avicularis 萹蓄 To relieve dysuria, to kill parasites and to alleviate itching./Urethritis, lithiasis, chyluria, dysentery, parotitis, heat strangury, short voidings of reddish urine, dripping with inhibited pain, eczema, pudendal itch, vaginal discharge, ascariasis.
TCMBANKHE006947 Aristolochia triangularis 三角马兜铃 See Aristolochia debilis./See Aristolochia debilis.
TCMBANKHE008925 Syringa pinnafolia 羽叶丁香 To warm center, downbear qi , warm kidney./Cold pain in stomach duct and abdomen, cold asthma, prolapse of uterus, prolapse of rectum.
TCMBANKHE006854/YNS-181/XU-60/XU-236 Arctium lappa L.|Arctium lappa 荜澄茄|牛蒡 牛蒡根 云南药材标准:第二册|西藏昌都市洛隆县 祛风清热,解毒消肿,力气通便。用于咽喉肿痛,牙龈肿痛,咳嗽痰稠,腹胀便秘,消渴;黄白带下,干血痨,产后少乳,风毒面肿,大头风,疮疡肿痛/Stomach cold with retching counterflow, distention fullness, cold pain in stomach duct and abdomen, rumbling intestines and diarrhea, cold mounting with abdominal pain, cold-damp dribbling urination and turbid urine.
TCMBANKHE004023/YEM-391/XU-797 Fructus Ligustri lucidi|Ligustrum lucidum Ait.|Ligustrum lucidum 女贞子|女贞 女贞子 云南民族药物志:第二卷|云南省文山州麻栗坡县 To replenish the liver and kidney, improve eyesight and promote the growth of black hair.;Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney./Septicemia, chronic bronchitis, acute dysentery, dizziness and tinnitus, premature graying in beard and hair, dim vision.;1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid. 阿昌族/德昂族/基诺族/景颇族/傈僳族/水族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1