Compound Summary


  Compound Information

药名:

epigallocatechin

别名:

Spectrum5_000889; (2S,3R)-2-(3,4,5-Trihydroxyphenyl)-chroman-3,5,7-triol; 08108_FLUKA; KBio2_003854; KBioSS_001286; epi-Gallocatechin; (−)-Epigallocatechin; SPBio_000885; Epigallocatechol; (2S,3S)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; AIDS-001348; Spectrum_000806; NCI60_026204; BCBcMAP01_000207; (2S,3S)-(+)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; MCULE-9338438267; CCRIS 5441; CHEBI:42255; Spectrum4_000950; 136892-45-0; (2R,3R)-2-(3,4,5-trihydroxyphenyl)chroman-3,5,7-triol; (3,3',4',5,5',7-Hexahydroxyflavan); (−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol; SCHEMBL1972938; (+)-epigallocatechin; AIDS001348; KBio3_001136; SDCCGMLS-0066479.P001; EGC; 1-epi-3',4',5,5',7-Pentahydroxy-3-Flavan; NSC674039; 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2R-cis)- (9CI); 970-74-1; E3768_SIAL; EPIGALLOCATECHIN; C12136; 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2R-cis)-; KBio2_006422; Antiscurvy factor C2; NCGC00180795-01; SpecPlus_000269; Factor C2 (antiscurvy); (-)cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (-)-3,3',4',5,5',7-Flavanhexol; 98032-84-9; l-Epigallocatechol; MolPort-001-740-311; 3,3',4',5,5',7-Flavanhexol; BSPBio_001636; (-)-Epigallocatechol; (2S,3S)-2-(3,4,5-Trihydroxy-phenyl)-chroman-3,5,7-triol; (-)-Epigallocatechin; (2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; 3BC1BF1C-D95B-4EB2-943E-C1F59C7501A0; KBio1_001309; (2S,3S)-epigallocatechin; KBioGR_001540; SPECTRUM205113; ZINC3870339; CHEBI:71227; (2S,3S)-flavan-3,3',4',5,5',7-hexol; CHEMBL130415; (+)-epi-gallocatechin; NP-000358; Spectrum3_000248; (−)-cis-3,3′,4′,5,5′,7-Hexahydroxyflavane; 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL; (+)-cis-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol; Antiscurvy factor C(sub 2); 2545-09-7; ACon1_000192; SMP1_000114; KBio2_001286; L-Epigallocatechin; DivK1c_006365; (2S,3S)-2-(3,4,5-TRIHYDROXYPHENYL)-3,4-DIHYDRO-2H-1-BENZOPYRAN-3,5,7-TRIOL; Spectrum2_000703; (+)-cis-3,3',4',5,5',7-hexahydroxyflavane; BDBM50135171; (2S,3S)-flavan-3,5,7,3',4',5'-hexol;l-epigallocatechin

分子式:

C15H14O7

Smiles:

C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O

成分:

HBIN025344;HBIN032938

OB_score:

24.182433

CAS_id:

98032-84-9

SymMap_id:

SMIT00658

TCMID_id:

23229;6920

TCMSP_id:

MOL006791

PubChem_id:

72277


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002044 Semen Phaseoli 赤小豆 To cause diuresis, to counteract toxicity, and to promote the drainage of pus./Decoction inhibits the growth of Staphylococcus aureus, Shigella flexneri and Bacillus typhoid in vitro.
TCMBANKHE002206 罗布麻叶
TCMBANKHE003237 毛果芍药
TCMBANKHE003524 Fructus Phyllanthi 余甘子 To remove heat from blood, to promote digestion and the production of body fluid, and to relieve cough./Treatment of heat in the blood and blood stasis, liver and gall bladder diseases, dyspepsia, abdominal pain, cough, sore throat, dryness of the mouth.
TCMBANKHE003734 radix tripterygii wilfordii 雷公藤 To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen.
TCMBANKHE003736 银杏叶
TCMBANKHE004244 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE004707 Radix Paeoniae Rubra; Lignum Paeoniae Rubra 赤芍 To remove heat from blood, to eliminate blood stasis, and to relieve pain./1. Paeoniflorin, one of its active components, has a strong antispastic effect and also analgesic, sedative, anticonvulsive, antibacterial and anti-imflammatory effects. 2. Dilating blood vessels, increasing coronary flow and improving myocardial oxygen supply. 3. Inhibiting platelets aggregation.
TCMBANKHE004858 白毛藤 Malaria, jaundice, edema, strangury, pain in joints due to rheumatalgia, erysipelas, clove sore.
TCMBANKHE005059 Cynanchum chinense 鹅绒藤 To clear heat and resolve toxin, disperse accumulation and fortify stomach, disinhibit water and disperse edema./Child food accumulation, child gan accumulation, gastritis, gastritis with edema, duodenal ulcer, wart.
TCMBANKHE005226 Rhizoma Dryriae 骨碎补 To replenish the kidney, to strengthen the bones, to promote the healing of fracture, and to relieve pain./Kidney vacuity lumbago, tinnitus and deafness, tooth mobilizing, wrenching and contusion from knocks and falls, sinew and bone wound, alopecia areata, white patch wind.
TCMBANKHE007669 香橼 See Citrus medica .
TCMBANKHE006209 Rhizoma Atractylodis 苍术 To remove damp and invigorate the function of the spleen, to disple wind-cold, and to improve eyesight./Spleen-stomach damp turbidity, fatigue hypodynamia, glomus in chest, abdominal distention, inappetence, vomiting and diarrhea, phlegm-rheum, damp edema, exterior damp, heavy head and generalized pain, damp impediment, aching pain in limbs, crippling wilt, night blindness.
TCMBANKHE008085 Xanthoceras sorbifolia 文冠木 To dispel wind and eliminate damp, disperse swelling and relieve pain./Wind-damp-heat impediment, pain in sinews and bones.
TCMBANKHE007449 Salacia prinoides [Syn. Salacia chinensis] 桫拉木 To expel wind and eliminate damp, free channels and quicken blood./Wind-damp impediment, blood stasis lumbago.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE009034 Fructus Polygoni Orientalis 水红花子 To reduce masses by dissipating blood stasis, and to relieve pain by removing stagnancy of food./Treatment of mass in the abdomen, goitre with pain, epigastric pain and distension due to indigestion.
TCMBANKHE008662 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE006108/XU-375 Acacia nilotica 阿拉伯胶金合欢|阿拉伯金合欢 四川省凉山州宁南县
TCMBANKHE006388/YEM-259/XU-440 Camellia sinensis [Syn. Thea sinensis]|Camellia sinensis (L.)O.Kuntze var.assamica(Masters)Kitam.|Camellia sinensis 茶叶|普洱茶|茶 普洱茶 云南民族药物志:第二卷|云南省昭通市盐津县 To clear head and eyes, eliminate vexation and allay thirst, disperse food, transform phlegm, disinhibit urine, resolve toxin./Headache, dim vision, red eyes, desire to sleep, common cold, vexation and thirst, food accumulation, bad breath, phlegm asthma, epilepsy, inhibited urination, diarrhea, throat swelling, swelling of sores and boils, burns and scalds. 傣族/哈尼族/彝族/藏族
TCMBANKHE005866/YEM-264 Myrica rubra|Myrica rubra (Lour.)Sieb.et Zucc. 杨梅树皮|杨梅 杨梅 云南民族药物志:第二卷 To rectify qi and dissipate stasis, eliminate damp, relieve pain./Dysentery, knocks and falls, eye screen, toothache, burns and scalds, malign scab and lai sore. 阿昌族/傣族/德昂族/景颇族/傈僳族/水族/彝族/壮族
TCMBANKHE004261/YNS-302/YEM-404/XU-755 Phyllanthus emblica|Phyllanthus emblica L. 庵摩勒|余甘子 余甘子树皮|滇橄榄 云南药材标准:第三册|云南民族药物志:第二卷|广东省廉江市石岭镇 解毒消肿,收敛止血,杀菌去腐,用于痈肿,疳疔疮毒,阴囊湿疹,外伤出血,跌打损伤,蛇虫叮咬。|To relieve cough and transform phlegm, engender liquid and allay thirst, resolve toxin./Common cold with fever, cough, throat pain, diphtheria, enteritis, diarrhea, eczema, heat vexation and thirst. 阿昌族/白族/布朗族/傣族/哈尼族/基诺族/拉祜族/傈僳族/纳西族/普米族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE006845/YNS-144/YEM-710 Lycoris radiata [Syn. Amaryllis radiata]|Lycoris radiata (L'Her.) Herb|Lycoris radiata(L‘Her.)Herb. 石蒜 老鸦蒜|石蒜 云南药材标准:第六册|云南民族药物志:第四卷 祛痰催吐,解毒消肿,活血散结,杀虫。用于食物中毒,咽喉肿痛,痰涎壅塞,痰核,瘰疬,痈疽肿毒。|To dispel phlegm and promote vomiting, resolve toxin and dissipate binds./Poliomyelitis, muscle weakness, rheumatic arthritis, pain in joints due to rheumatalgia, throat wind, nipple moth, swelling pain in throat, phlegm-drool and congesting lung, food poisoning, seeper in chest and abdomen, malign sore and swelling toxin, hemorrhoids and fistulas, knocks and falls, intractable lichen, burns and scalds, snake bite. 水族/彝族
TCMBANKHE005898/YNS-113/YEM-98/XU-75 Tripterygium hypoglaucum|Tripterygium hypoglaucu (Lévl.) Hutch.|Tripterygium hypoglaucum (Lévl. )Lévl.ex ex Hutch. 昆明山海棠 火把花根|昆明山海棠 云南药材标准:第二册|云南民族药物志:第一卷|云南省保山市隆阳区瓦房乡 祛风除湿,舒经通络,消肿止痛。用于风寒湿痹,关节肿痛,跌倒损伤,红斑狼疮,皮痹瘙痒骨痨骨疽,睾丸结核|To dispel wind and eliminate damp, quicken blood and stanch bleeding, soothe sinews and joint bones, resolve toxin and kill worms./Rheumatic arthritis, wind-damp impediment pain, hemiplegia, mounting qi , dysmenorrhea, profuse menstruation, postpartum abdominal pain, incessant bleeding, acute infectious hepatitis, chronic nephritis, erythematous lupus, fracture, medullitis, bone tuberculosis, epididymis tubercle, sore toxin, psoriasis, neurodermatitis. 哈尼族/拉祜族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000204 CXCL8 GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 C-X-C motif chemokine ligand 8
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000247 SLC2A4 GLUT4 solute carrier family 2 member 4
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005226 LDHA GSD11; HEL-S-133P; LDHM; PIG19 lactate dehydrogenase A
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE012981 LDHB HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5 lactate dehydrogenase B
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1