Compound Summary


  Compound Information

药名:

(2S)-liquiritigenin;liquiritigenin;DFV

别名:

(2R)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; N1793; AJ-23291; AC1LICLD; ZINC519174;4',7-Dihydroxyflavanone; 5-DEOXYFLAVANONE; 578-86-9; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (S)-; 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE; (2S)-7-hydroxy-2-(4-hydroxyphenyl)chroman-4-one; (2S)-7-Hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one; ZINC00985403; 2885-30-5; 17002-53-8; C09762; Liquiritigenin; 7,4'-Dihydroxyflavanone; (2S)-7-hydroxy-2-(4-hydroxyphenyl)-4-chromanone; STOCK1N-11167; 16006-91-0

分子式:

C15H12O4

Smiles:

C1C(OC2=C(C1=O)C=CC(=C2)O)C3=CC=C(C=C3)O

成分:

HBIN006815;HBIN033376;HBIN023519

OB_score:

32.762724

CAS_id:

578-86-9

SymMap_id:

SMIT16317;SMIT04150

TCMID_id:

35697;12902

TCMSP_id:

MOL001792

PubChem_id:

114829


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000312 Radix Glycyrrhizae Preparata 炙甘草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE001997 金盏菊花
TCMBANKHE003151 Dalbergia stevensonii
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE004366 Cicer arietinum 回回豆 To clear heat and resolve toxin./Diabetes mellitus.
TCMBANKHE004384 Epimedium koreanum 朝鲜淫羊藿 See Epimedium brevicornum ./See Epimedium brevicornum.
TCMBANKHE004862 Lignum Dalbergiae odoriferae Rosewood 降香 To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits.
TCMBANKHE004922 Datura innoxia 毛曼陀罗叶 See Datura metel./See Datura metel.
TCMBANKHE007546 Glycyrrhiza inflata 胀果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis.
TCMBANKHE005732 Dalbergia odorifera 降真香 To quicken blood and dissipate stasis, stanch bleeding and settle pain, downbear qi , break foul./Chest and rib-side pain, knocks and falls, bleeding due to external injury, bleeding due to external injury.
TCMBANKHE006338 Glycyrrhiza glabra 光果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .
TCMBANKHE005104/XU-626/XU-651 Robinia pseudoacacia 刺槐花|刺槐 贵州省毕节市金沙县 To stanch bleeding./Precipitate blood of large intestine, hemoptysis, flooding.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE007155 Radix Scrophulariae 玄参; 元参 To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity. Treatment of febrile diseases with impairment of yin manifested by deep red tongue and dire thirst, or with eruptions, constipation due to impairment of body fluid, phthisis with cough, conjunctivitis, sore throat, scrofula, diphtheria, boils and sores./Heat entering construction-blood, generalized fever, vexation and thirst, crimson tongue, macular eruption, steaming bone taxation cough, vacuity vexation and insomnia, fluid damage and constipation, dry eyes with clouded flowery vision, swelling pain in throat, scrofula with phlegm node, sore toxin of welling abscess and flat abscess. 1. Its alcoholic extract and its component methoxycinnamic acid can lower the typhoid vaccine-induced fever in rabbits.2. Its water or alcoholic infusion and decoction exert a mild hypotensive effect on anesthetized animals3. Lowering the level of blood sugar.4. Its infusion inhibits the growth of some dermatomyces.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE008647 Apis mellifera ligustica 蜂胶 To eliminate inflammation and relieve pain, moisten skin and engender flesh./Gastric ulcer, oral ulcer, cervical erosion, zoster, psoriasis, skin chap and pain, clavus, wound, carcinoma.
TCMBANKHE006169/YEM-108 Fructus Liquidambaris|Liquidambar formosana Hance. 路路通|枫香树 路路通 云南民族药物志:第一卷 To dispel wind and remove obstruction from the collaterals, to cause diuresis, and to stimulate menstrual discharge./Wind-damp impediment pain, numbness in limbs, hypertonicity of limbs, pain in stomach duct and abdomen, amenorrhea, galactostasis, edema distention fullness, eczema. 彝族
TCMBANKHE008102/YEM-642 Herba Sedi sarmentosi|Sedum sarmentosum Bunge 垂盆草 垂盆草 云南民族药物志:第四卷 To remove damp-heat, and to counteract toxicity./1. Its amino acid protect the liver of rats and mice from CCl4 damage.2. Inhibiting the growth of Staphyloccus aureus, (a0 and (B) streptococcus and Shigella flexneri in vitro. 苗族/水族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007651 NOTCH2 AGS2; HJCYS; hN2 notch receptor 2
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1