Compound Summary

  Compound Information

TCMBANKIN058581

药名:	GBL
别名:	1,4-Lactone; 2-tetrahydrofuranone; Gamma-Lactone 4-hydroxy-butyric acid; CHEBI:42639; B103608_ALDRICH; Butyric acid lactone; gamma-Hydroxybutyric acid cyclic ester; 4-Hydroxybutanoic acid, .gamma.-lactone; oxolan-2-one; 1,4-Butyrolactone; .gamma.-6480; .gamma.-Hydroxybutyric acid lactone; gamma-Hydroxybutyric acid lactone; Butanoic acid, 4-hydroxy-, .gamma.-lactone; ZINC04658567; Butyryl lactone; gamma-Butyrolactone (natural); gamma-6480; 4-Deoxytetronic acid; NSC4592; 2-Oxolanone; .gamma.-Butyrolactone; HSDB 4290; .gamma.-BL; 187997-16-6; NCI-C55878; EINECS 202-509-5; 4-Hydroxybutyric acid, .gamma.-lactone; 4-Butanolide; 4-Butyrolactone; AI3-28121; gamma-BL; tetrahydrofuran-2-one; Tetrahydro-2-furanone; NSC 4592; CCRIS 2924; EPA Pesticide Chemical Code 122303; Caswell No. 132B; FEMA No. 3291; Gamma-Lactone 4-hydroxybutanoic acid; Butyrylactone; 4-Hydroxybutanoic acid lactone; C-1070; 2(3H)-Furanone, dihydro-; C01770; 1,2-Butanolide; 3-Hydroxybutyric acid lactone; 4-Hydroxybutyric acid lactone; No Go; Dihydro-2-furanone; 1,4-Butanolide; .gamma.-Hydroxybutyric acid cyclic ester; Gamma-Butanolactone; gamma-Hydroxybutyrolactone; InChI=1/C4H6O2/c5-4-2-1-3-6-4/h1-3H; Gamma-Lactone 4-hydroxybutyric acid; .alpha.-Butyrolactone; c0033; Dihyro-2-furanone; .gamma.-Hydroxybutyrolactone; W329118_ALDRICH; BLO; Butyric acid, 4-hydroxy-, gamma-lactone; Agrisynth BLO; Butanoic acid, 4-hydroxy-, gamma-lactone; Gamma-Lactone 4-hydroxy-butanoic acid; dihydrofuran-2(3H)-one; 96-48-0; Alpha-Butyrolactone; Dihydro-2(3H)-furanone; BLON; Butyrolactone; WLN: T5OVTJ; Butyric acid, 4-hydroxy-, .gamma.-lactone; 2-Oxotetrahydrofuran; LS-2010; BUTANOIC ACID,4-HYDROXY,LACTONE GAMMA-BUTYROLACTONE; gamma-Butyrolactone; 1-Oxacyclopentane-2-one; γ- Butyrolactone; Butyrolactone
分子式:	C4H6O2
Smiles:	C1CC(=O)OC1
成分:	HBIN027401; HBIN019157; HBIN049104
OB_score:	76.90596
CAS_id:	187997-16-6
SymMap_id:	SMIT04793
TCMID_id:	33571;36342
TCMSP_id:	MOL002576
PubChem_id:	7302

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003672	Succus Bambusae	竹沥			To clear heat and resolve phlegm/Treatment of: 1. Phlegm-heat cough manifested as cough with thick, yellow sputum and chest pain. Bamboo juice (Zhuli) is used with Loquat leaf (Pipaye) and Trichosanthes fruit (Gualou). 2. Windstroke due to heart misted by phlegm, epilepsy or manic psycho
TCMBANKHE004515	Hericium erinaceus	猴头菇			To benefit vital Qi, invigorate the spleen and nourish the stomach. For hypofunction of the spleen and stomach, peptic ulcer and chronic gastritis. Recently, also used for the cancers of erophagus, stomach and intestines./To benefit vital Qi, invigorate the spleen and nourish the stomach. For hypofunction of the spleen and stomach, peptic ulcer and chronic gastritis. Recently, also used for the cancers of erophagus, stomach and intestines.
TCMBANKHE004973	Herba Ephedrae	麻黄			To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.
TCMBANKHE006907		高良姜			Cold pain in stomach duct and abdomen, vomiting, diarrhea.
TCMBANKHE007520	Fructus Amomi	砂仁			To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy.
TCMBANKHE005628/YEM-121	Fructus Chaenomelis|Chaenomeles speciosa (Sweet) Nakai	木瓜|皱皮木瓜	木瓜	云南民族药物志：第一卷	To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema.	傣族/景颇族/苗族/彝族/藏族
TCMBANKHE004691/YEM-353/YEM-961	Fructus Amomi|Amomum villosum Lour.	缩砂仁; 砂仁|阳春砂	阳春砂仁	云南民族药物志：第五卷	Treatment of accumulation of damp in the spleen and the stomach marked by epigastric stuffieness and anorexia, vomiting and diarrhea in deficiency cold syndrome of the spleen and the stomach, pernicious vomiting of pregnancy, threatened abortion.; To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./1. Its decoction lower thab 1% concentration stimulates and that higher than 1% or the saturated solution of its volatile oil inhibits the intestines of guinea-pigs in vitro.2. Its volatile oil acts as stomachic tonic and exaggerates the diacharge of flatus.; Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy.	阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/瑶族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000449	CCK	-	cholecystokinin
TCMBANKGE000461	RCVRN	RCV1	recoverin
TCMBANKGE000568	MET	AUTS9; DFNB97; HGFR; RCCP2; c-Met	MET proto-oncogene, receptor tyrosine kinase
TCMBANKGE000697	APAF1	APAF-1; CED4	apoptotic peptidase activating factor 1
TCMBANKGE001274	EFCAB11	C14orf143	EF-hand calcium binding domain 11
TCMBANKGE001410	MYL3	CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl	myosin light chain 3
TCMBANKGE001510	WDR5B	-	WD repeat domain 5B
TCMBANKGE001647	PVALB	D22S749	parvalbumin
TCMBANKGE001827	MYL7	MYL2A; MYLC2A	myosin light chain 7
TCMBANKGE002052	CIB1	CIB; CIBP; KIP1; PRKDCIP; SIP2-28	calcium and integrin binding 1
TCMBANKGE002096	EFCAB6	DJBP; HSCBCIP1; dJ185D5.1	EF-hand calcium binding domain 6
TCMBANKGE002273	EFCAB9	-	EF-hand calcium binding domain 9
TCMBANKGE002334	TEP1	TLP1; TP1; TROVE1; VAULT2; p240	telomerase associated protein 1
TCMBANKGE002509	TNNC2	CFAP85; FAP85	troponin C2, fast skeletal type
TCMBANKGE002710	EFCAB1	-	EF-hand calcium binding domain 1
TCMBANKGE002868	CALML4	NY-BR-20	calmodulin like 4
TCMBANKGE002979	MYL9	LC20; MLC-2C; MLC2; MRLC1; MYRL2	myosin light chain 9
TCMBANKGE003018	CIB3	KIP3	calcium and integrin binding family member 3
TCMBANKGE003357	MYL5	MYLC2	myosin light chain 5
TCMBANKGE003406	WDR88	PQWD	WD repeat domain 88
TCMBANKGE003672	CALM1	CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM	calmodulin 1
TCMBANKGE004362	CETN3	CDC31; CEN3	centrin 3
TCMBANKGE004413	EFCAB2	CFAP200; DRC8	EF-hand calcium binding domain 2
TCMBANKGE004510	NLE1	NLE	notchless homolog 1
TCMBANKGE004566	CIB2	DFNB48; KIP2; USH1J	calcium and integrin binding family member 2
TCMBANKGE004982	OGA	MEA5; MGEA5; NCOAT	O-GlcNAcase
TCMBANKGE005023	EFCAB7	-	EF-hand calcium binding domain 7
TCMBANKGE005037	CALB2	CAB29; CAL2; CR	calbindin 2
TCMBANKGE005074	CABP1	CALBRAIN; HCALB_BR	calcium binding protein 1
TCMBANKGE005186	PPP3R1	CALNB1; CNB; CNB1	protein phosphatase 3 regulatory subunit B, alpha
TCMBANKGE005397	WSB2	SBA2	WD repeat and SOCS box containing 2
TCMBANKGE005420	MYLPF	HUMMLC2B; MLC2B; MRLC2; MYL11	myosin light chain, phosphorylatable, fast skeletal muscle
TCMBANKGE005504	CALN1	CABP8	calneuron 1
TCMBANKGE005605	HPCA	BDR2; DYT2	hippocalcin
TCMBANKGE006037	MYL1	MLC1F; MLC3F; MYOFTA	myosin light chain 1
TCMBANKGE006052	WDR61	REC14; SKI8	WD repeat domain 61
TCMBANKGE006265	MYL10	MYLC2PL; PLRLC	myosin light chain 10
TCMBANKGE006439	CABP7	CALN2	calcium binding protein 7
TCMBANKGE006587	MYL12B	MLC-B; MRLC2	myosin light chain 12B
TCMBANKGE007011	CFAP52	WDR16; WDRPUH	cilia and flagella associated protein 52
TCMBANKGE007334	GUCA1C	GCAP3	guanylate cyclase activator 1C
TCMBANKGE007590	CALML5	CLSP	calmodulin like 5
TCMBANKGE007780	KCNIP1	KCHIP1; VABP	potassium voltage-gated channel interacting protein 1
TCMBANKGE007873	VSNL1	HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1	visinin like 1
TCMBANKGE008005	CHP2	-	calcineurin like EF-hand protein 2
TCMBANKGE008299	OCM	OCM1; OM; ONCM	oncomodulin
TCMBANKGE008414	CALML3	CLP	calmodulin like 3
TCMBANKGE008718	PRSS3	MTG; PRSS4; T9; TRY3; TRY4	serine protease 3
TCMBANKGE009113	GUCA1A	C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1	guanylate cyclase activator 1A
TCMBANKGE009343	CABP2	DFNB93	calcium binding protein 2
TCMBANKGE009389	LYZ	LYZF1; LZM	lysozyme
TCMBANKGE009753	KCNIP3	CSEN; DREAM; KCHIP3	potassium voltage-gated channel interacting protein 3
TCMBANKGE009764	CALB1	CALB; D-28K	calbindin 1
TCMBANKGE009936	CALML6	CAGLP	calmodulin like 6
TCMBANKGE010133	MYL4	ALC1; AMLC; GT1; PRO1957	myosin light chain 4
TCMBANKGE010792	CABP5	CABP3	calcium binding protein 5
TCMBANKGE010848	PAFAH1B1	LIS1; LIS2; MDCR; MDS; NudF; PAFAH	platelet activating factor acetylhydrolase 1b regulatory subunit 1
TCMBANKGE011054	KCNIP4	CALP; KCHIP4	potassium voltage-gated channel interacting protein 4
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE011185	TESC	CHP3; TSC	tescalcin
TCMBANKGE011318	NCS1	FLUP; FREQ	neuronal calcium sensor 1
TCMBANKGE011526	MYL12A	HEL-S-24; MLC-2B; MLCB; MRCL3; MRLC3; MYL2B	myosin light chain 12A
TCMBANKGE011677	WDR5	BIG-3; CFAP89; SWD3	WD repeat domain 5
TCMBANKGE011863	CETN1	CEN1; CETN	centrin 1
TCMBANKGE011890	CABP4	CRSD; CSNB2B	calcium binding protein 4
TCMBANKGE012123	HPCAL1	BDR1; HLP2; VILIP-3	hippocalcin like 1
TCMBANKGE012440	EFCAB3	-	EF-hand calcium binding domain 3
TCMBANKGE012539	RHBDL3	RHBDL4; VRHO	rhomboid like 3
TCMBANKGE012566	MYL2	CMH10; MLC-2s/v; MLC2	myosin light chain 2
TCMBANKGE012607	HPCAL4	HLP4	hippocalcin like 4
TCMBANKGE012791	TNNC1	CMD1Z; CMH13; TN-C; TNC; TNNC	troponin C1, slow skeletal and cardiac type
TCMBANKGE012844	PPP3R2	PPP3RL	protein phosphatase 3 regulatory subunit B, beta
TCMBANKGE012999	CHP1	CHP; SLC9A1BP; SPAX9; Sid470p; p22; p24	calcineurin like EF-hand protein 1
TCMBANKGE013040	EFCAB13	C17orf57	EF-hand calcium binding domain 13
TCMBANKGE013263	MYL6	ESMLC; LC17; LC17-GI; LC17-NM; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM	myosin light chain 6
TCMBANKGE013287	KCNIP2	KCHIP2	potassium voltage-gated channel interacting protein 2
TCMBANKGE013316	GUCA1B	GCAP 2; GCAP2; GUCA2; RP48	guanylate cyclase activator 1B
TCMBANKGE013638	SPATA21	spergen-2; spergen2	spermatogenesis associated 21
TCMBANKGE013661	CIB4	KIP4	calcium and integrin binding family member 4
TCMBANKGE013829	CETN2	CALT; CEN2	centrin 2
TCMBANKGE013890	SCGN	CALBL; DJ501N12.8; SECRET; SEGN; setagin	secretagogin, EF-hand calcium binding protein
TCMBANKGE014015	BCHE	BCHED; CHE1; CHE2; E1	butyrylcholinesterase
TCMBANKGE014276	NCALD	-	neurocalcin delta
TCMBANKGE014683	OCM2	OCM; OM	oncomodulin 2