Compound Summary


  Compound Information

药名:

rutacarpine

别名:

rutaecarpine;rutecarpine

分子式:

C18H13N3O

Smiles:

C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4

成分:

HBIN042651;HBIN042669;HBIN042657

OB_score:

40.30046

CAS_id:

84-26-4

SymMap_id:

SMIT00162

TCMID_id:

35085;25349;19066

PubChem_id:

65752


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000518 少果吴茱萸
TCMBANKHE001184 毛脉吴茱萸
TCMBANKHE002173 Stigma Croci 西红花 To activate blood circulation and eliminate blood stasis, to remove heat from blood and counteract toxicity, and to calm the nerves./Treatment of amenrrhea with abdominal mass formation, blood stasis after childbirth, eruptions in infectious diseases, emotional dejection, mania.
TCMBANKHE002993 灯台叶
TCMBANKHE003083 吴茱萸叶
TCMBANKHE003391 Evodia baberi 一花吴茱萸
TCMBANKHE003626 Ruta chalepensis 穗状芸香
TCMBANKHE008047 Ruta graveolens 臭草 To dispel wind, abate fever, disinhibit urine, quicken blood, resolve toxin, disperse swelling./Common cold with fever, wind-damp bone pain, infant fright wind, inhibited urination, diarrhea, mounting qi, amenorrhea, knocks and falls, heat toxin sores, eczema.
TCMBANKHE006061 Fructus Evodiae 吴茱萸 1. To dispel cold and stop pain; 2. To pacify the liver and direct rebellious qi downward; 3. To stop vomiting/Dysentery, cold pain in stomach duct and abdomen, reverting yin headache, mounting qi , dysmenorrhea, beriberi with edema, hyperchlorhydria, cold-damp diarrhea.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007462 青风藤 Wind-damp impediment pain, pain from arthritis, swelling in joints, paralytic and pruritus.
TCMBANKHE009079 Phellodendron japonicum 日本黄柏
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE004238/YEM-1014 Phellodendron amurense;Cortex Phellodendri|Phellodendron chinense Schneid var.glabriusculum Schneid. 黄柏|秃叶黄蘗 广西黄柏 云南民族药物志:第五卷 1. To clear heat and dry dampness; 2. To reduce fire and release toxins/Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission. 瑶族/壮族
TCMBANKHE004506/YEM-137 Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. 三七 三七 云南民族药物志:第一卷 To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. 彝族
TCMBANKHE004189/YEM-163 Evodia rutaecarpa var. officinalis|Evodia rutaecarpa (Juss.) Benth. 石斛果|吴茱萸 吴茱萸 云南民族药物志:第一卷 See Evodia rutaecarpa ./See Evodia rutaecarpa. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE002126/YEM-163 Fructus Evodiae|Evodia rutaecarpa (Juss.) Benth. 吴芋|吴茱萸 吴茱萸 云南民族药物志:第一卷 Treatment of headache accompanied by retching and cold limbs, abdominal colic, weakness and edema of the legs, abdominal pain during menstruation, epigastric distension and pain with vomiting and acid regurgitation, diarrhea occurring before dawn daily, hypertension. External use for ulcers in the mouth./1. Its volatile oil containing evoden inhibits the abnormal fermentation in the intestine.2. Evodin, evodiamine and rutaecarpine, are active components for analgesic.3. Oral administration or injection can lower blood pressure in normal animals or those with renal hypertension. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE008832/YEM-163 Evodia rutaecarpa var. bodinieri|Evodia rutaecarpa (Juss.) Benth. 波士吴茱萸|吴茱萸 吴茱萸 云南民族药物志:第一卷 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE000949/YEM-163 Evodia rutaecarpa (Juss.) Benth. 吴茱萸根|吴茱萸 吴茱萸 云南民族药物志:第一卷 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000315 IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4 interleukin 4
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000458 CYP2B6 CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450 cytochrome P450 family 2 subfamily B member 6
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001008 CYP3A4 CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1 cytochrome P450 family 3 subfamily A member 4
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001079 CYP1A1 AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001080 AHR RP85; bHLHe76 aryl hydrocarbon receptor
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006993 AHRR AHH; AHHR; bHLHe77 aryl-hydrocarbon receptor repressor
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE009543 LTA LT; TNFB; TNFSF1; TNLG1E lymphotoxin alpha
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE015090 CYP1A2 CP12; CYPIA2; P3-450; P450(PA) cytochrome P450 family 1 subfamily A member 2