Compound Summary
Compound Information
药名: | lycorine |
别名: | AC-20268; CHEMBL583716; 2-epi-Lycorine; ZINC21992900; AKOS015965245; Licorine; NCI60_003767; UNII-I9Q105R5BU; ST24047513; Amarylline; HMS3402B04; QTL1_000052; AN-24834; HMS1989B04; 3,3a-Didehydrolycoran-1alpha,2beta-diol; NSC-683873; AN-50515; AJ-46629; AX8136904; KBio3_000043; 3,12-[methylenebis(oxy)]-galanthan-1.alpha.,2.beta.-diol; MolPort-000-882-129; Galanthidine; Bio2_000022; KBioSS_000022; Lycorine hydrochloride; DTXSID60197208; NCGC00163413-02; EINECS 207-503-6; KBio2_005158; ZINC3881372; KBio2_000022; AC1L2HYJ; 2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, (1S,2S,12bS, 12cS)-; CHEBI:6601; SC-19266; CCG-208232; GNF-PF-4974; KBio3_000044; C08532; LS-88398; AC1Q6ZRB; Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-; MFCD00243111; Lycoran-1alpha,2beta-diol, 3,3a-didehydro- (8CI); SCHEMBL626071; NSC683873; Bio2_000502; (-)-Lycorine; CHEMBL400092; IDI1_033772; KBioGR_000022; KBio2_002590; BDBM50221066; HMS1361B04; NSC-401360; Likorin; MFCD00221746; NSC 401360; NCGC00163413-01; I9Q105R5BU; BSPBio_001302; 9,10-(methylenedioxy)-3,12-didehydrogalanthan-1alpha,2beta-diol; lycorine; MCULE-4471227410; BRD-K64909280-001-02-7; Galanthan-1, 3,4-didehydro-11,12-[methylenebis(oxy)]-, (1.alpha.,2.beta.)-; Lycoran-1alpha,2beta-diol, 3,3a-didehydro-; 476-28-8; Galanthan-1, 3,12-didehydro-9,10-[methylenebis(oxy)]-, (1.alpha.,2.beta.)-; Lycoran-1.alpha., 3,3a-didehydro-; BCBcMAP01_000100; NSC401360; HMS1791B04; Galanthan-1,2-diol, 3,12-didehydro-9,10-(methylenebis(oxy))-, (1-alpha,2-beta)-; ST085774; STOCK1N-67168; SMP1_000184; Narcissine; Galanthan-1,2-diol, 3,12-didehydro-9,10-(methylenebis(oxy))-, (1-alpha,2-beta)- (9CI); AK115153; 3,2.beta.-diol; 2,5,7,12b,12c-Hexahydro-1H-[1,3]-dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol; AKOS000278045; (-)-lycorine; narcissine |
分子式: | C16H17NO4 |
Smiles: | C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4 |
成分: | HBIN034010; HBIN034011; HBIN036348 |
OB_score: | 12.615661 |
CAS_id: | 2188-68-3 |
SymMap_id: | SMIT00555;SMIT02377 |
TCMID_id: | 13234;24999 |
TCMSP_id: | MOL004136 |
PubChem_id: | 72378 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE003738 | Aloe | 芦荟 | 1. To purge feces; 2. To clear heat in the liver; 3. To kill worms/Constipation, child gan accumulation, ascariasis, fright wind, lichen. | |||
| TCMBANKHE003907 | Crinum latifolium | 西南文殊兰 | To quicken blood and dispel stasis, free network vessels and relieve pain, clear heat and resolve toxin./Wound swelling from knocks and falls, fracture, pain in joints, toothache, malign sore and swelling toxin, hemorrhoids, zoster, psoriasis. | |||
| TCMBANKHE004018 | Pseudobulbus Cremastrae seu Pleiones;Asarum sagittarioides | 山慈菇 | To remove toxic heat, and to dissolve lumps./Common cold, stomachache, toothache, knocks and falls, snake bite. | |||
| TCMBANKHE004233 | Hymenocallis littoralis | 水鬼蕉叶 | To soothe sinews and quicken blood, disperse swelling and relieve pain./Painful swelling from knocks and falls, pain in joints due to rheumatalgia, hemorrhoids. | |||
| TCMBANKHE006518 | Crinum macowanii | 灌木文殊兰 | ||||
| TCMBANKHE005437 | Leucojum vernum | 雪片莲 | ||||
| TCMBANKHE007485 | Amaryllis belladonna | 孤挺花 | ||||
| TCMBANKHE005669 | Pericarpium Citri Reticulatae Viride | 青皮 | To soothe the liver, to disintegrate stagnated qi, and to remove retained food./1. Its component limonene is an expectorant and antiasthmatic.2. Its decoction relaxes the smooth muscle of intestines, stomach, gallbladder and uterus. | |||
| TCMBANKHE008278 | Narcissus pseudonarcissus | 黄水仙 | ||||
| TCMBANKHE006180 | 君子兰 | |||||
| TCMBANKHE008522 | Lycoris sanguinea | 铁色箭 | ||||
| TCMBANKHE007585 | Zephyranthes candida | 肝风草 | To calm liver and extinguish wind./Infant fright wind, epilepsy, tetanus. | |||
| TCMBANKHE005461/YEM-426 | Rhizoma Curculiginis|Curculigo orchioides Gaertn. | 仙茅 | 仙茅 | 云南民族药物志：第三卷 | To reinforce the kidney yang, to strengthen the tendons and bones,and to dispel cold-damp./Impotence seminal cool, limp wilting sinew and bone, cold impediment in lumbus and knees, yang vacuity cold diarrhea. | 阿昌族/白族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/苗族/佤族/彝族/壮族 |
| TCMBANKHE005494/YEM-445 | Fructus Hordei Germitus|Hordeum vulgare L. | 麦芽|大麦 | 大麦 | 云南民族药物志：第三卷 | To invigo rate the function of the spleen, to regulate the function of the stomach, and to promote the flow of milk./Food accumulation, abdominal distention and diarrhea, nausea and vomiting, inappetence, galactostasis, distending pain in breast. | 佤族/彝族 |
| TCMBANKHE006845/YNS-144/YEM-710 | Lycoris radiata [Syn. Amaryllis radiata]|Lycoris radiata (L'Her.) Herb|Lycoris radiata(L‘Her.)Herb. | 石蒜 | 老鸦蒜|石蒜 | 云南药材标准：第六册|云南民族药物志：第四卷 | 祛痰催吐，解毒消肿，活血散结，杀虫。用于食物中毒，咽喉肿痛，痰涎壅塞，痰核，瘰疬，痈疽肿毒。|To dispel phlegm and promote vomiting, resolve toxin and dissipate binds./Poliomyelitis, muscle weakness, rheumatic arthritis, pain in joints due to rheumatalgia, throat wind, nipple moth, swelling pain in throat, phlegm-drool and congesting lung, food poisoning, seeper in chest and abdomen, malign sore and swelling toxin, hemorrhoids and fistulas, knocks and falls, intractable lichen, burns and scalds, snake bite. | 水族/彝族 |
| TCMBANKHE004131/YEM-712 | Narcissus tazetta var. chinensis|Narcissus tazetta L.var.chinensis Roem | 水仙根|水仙 | 水仙 | 云南民族药物志：第四卷 | To clear heat and resolve toxin, dissipate stasis and disperse swelling./Swelling toxin of sore and welling abscess, insect bites, fish bone stuck in throat. | 阿昌族/傣族/德昂族/景颇族/傈僳族 |
| TCMBANKHE007081/YEM-712 | Narcissus tazetta var. chinensis|Narcissus tazetta L.var.chinensis Roem | 水仙花|水仙 | 水仙 | 云南民族药物志：第四卷 | To clear heart and quiet spirit, rectify qi and regulate menstruation, resolve toxin and repel foulness./Fatigued spirit and dizziness, menstrual disorder, dysentery, swelling of sores. | 阿昌族/傣族/德昂族/景颇族/傈僳族 |
| TCMBANKHE005781/YEM-73 | Lycoris aurea|Lycoris aurea(L'Hér)Herb. | 大一枝箭|忽地笑 | 忽地笑 | 云南民族药物志：第一卷 | To moisten lung and relieve cough, resolve toxin and disperse swelling./Lung heat cough, hemoptysis, yin vacuity consumption fever, inhibited urination, swelling toxin of welling abscess and sore, clove sore tubercle, burns and scalds. | 哈尼族/傈僳族/藏族 |
| TCMBANKHE005242/YEM-926 | Crinum asiaticum|Crinum asiaticum L.var.sinicum(Roxb.ex Herb.)Baker | 亚洲文殊兰|文殊兰 | 文殊兰 | 云南民族药物志：第五卷 | 傣族/哈尼族/苗族/瑶族/壮族 | |
| TCMBANKHE006146/YEM-926 | Crinum asiaticum var. japonicum|Crinum asiaticum L.var.sinicum(Roxb.ex Herb.)Baker | 日本文殊兰|文殊兰 | 文殊兰 | 云南民族药物志：第五卷 | 傣族/哈尼族/苗族/瑶族/壮族 | |
| TCMBANKHE006879/YEM-926 | Crinum asiaticum var. sinicum|Crinum asiaticum L.var.sinicum(Roxb.ex Herb.)Baker | 文殊兰 | 文殊兰 | 云南民族药物志：第五卷 | To clear heat and resolve toxin, dispel stasis and relieve pain./Cough, throat pain, knocks and falls, toothache. | 傣族/哈尼族/苗族/瑶族/壮族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
| TCMBANKDI007361 | Multiple Myeloma | disease | Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases | 27924158 |
| TCMBANKDI026275 | Glioblastoma | disease | Neoplasms | 30016965 |
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000192 | CDH5 | 7B4; CD144 | cadherin 5 |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000241 | CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | caspase 8 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE000294 | CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | cyclin dependent kinase inhibitor 1A |
| TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
| TCMBANKGE000633 | ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | adrenoceptor beta 2 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
| TCMBANKGE000965 | CHRNA7 | CHRNA7-2; NACHRA7 | cholinergic receptor nicotinic alpha 7 subunit |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE001131 | CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | caspase 9 |
| TCMBANKGE001132 | BAX | BCL2L4 | BCL2 associated X, apoptosis regulator |
| TCMBANKGE001148 | VEGFA | MVCD1; VEGF; VPF | vascular endothelial growth factor A |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE001166 | BCL2 | Bcl-2; PPP1R50 | BCL2 apoptosis regulator |
| TCMBANKGE001170 | CDK4 | CMM3; PSK-J3 | cyclin dependent kinase 4 |
| TCMBANKGE001506 | ADRA1B | ADRA1; ALPHA1BAR | adrenoceptor alpha 1B |
| TCMBANKGE001991 | CCND3 | - | cyclin D3 |
| TCMBANKGE003157 | CHRM2 | HM2 | cholinergic receptor muscarinic 2 |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE005535 | CHRM1 | HM1; M1; M1R | cholinergic receptor muscarinic 1 |
| TCMBANKGE006943 | CHRM3 | EGBRS; HM3; PBS | cholinergic receptor muscarinic 3 |
| TCMBANKGE008124 | ADRA2B | ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR | adrenoceptor alpha 2B |
| TCMBANKGE008253 | SEMA4D | A8; BB18; C9orf164; CD100; COLL4; GR3; M-sema-G; SEMAJ; coll-4 | semaphorin 4D |
| TCMBANKGE008702 | OPRM1 | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM | opioid receptor mu 1 |
| TCMBANKGE009455 | CHRM5 | HM5 | cholinergic receptor muscarinic 5 |
| TCMBANKGE011923 | CHRM4 | HM4; M4R | cholinergic receptor muscarinic 4 |
| TCMBANKGE014625 | OPRD1 | DOP; DOR; DOR1; OPRD | opioid receptor delta 1 |
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