Compound Summary

  Compound Information

TCMBANKIN058656

药名:	aristolochic acidⅡ
别名:	aristolochic acid B
分子式:	C16H9NO6
Smiles:	C1OC2=C(O1)C3=C(C(=C2)C(=O)O)C(=CC4=CC=CC=C43)[N+](=O)[O-]
成分:	HBIN016799;HBIN016806
SymMap_id:	SMIT11794
TCMID_id:	1716
TCMSP_id:	MOL010804
PubChem_id:	108168

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004385	Fructus Aristolochiae	马兜铃			To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine./Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema.
TCMBANKHE004913	Aristolochia mollissima	绵毛马兜铃			To dispel wind and eliminate damp, quicken blood and free network vessels, relieve pain./Wind-damp impediment pain, numbness in limbs, hypertonicity of sinews and bones, pain in stomach duct and abdomen, painful wound from knocks and falls, bleeding due to external injury, mammary welling abscess, suppurative infection.
TCMBANKHE008697	Caulis Aristolochiae seu Clematis	木通			1. To promote water metabolism and relieve abnormal urination; 2. To clear heat and promote lactation/Acute urethritis, short voidings of reddish urine, strangury-turbidity, edema, nephritis with edema, galactostasis, heat vexation in chest, throat pain, mouth sore, tongue sores, wind-damp impediment pain, galactostasis, amenorrhea, dysmenorrhea.
TCMBANKHE004227/XU-506	Aristolochia manshuriensis	关木通|木通马兜铃		云南省红河州金平县	To clear heart fire, disinhibit urine, free menstruation and milk./Mouth sore, tongue sores, vexation and reddish urine, edema, heat strangury with inhibited pain, leukorrhea, amenorrhea and scant milk, damp-heat impediment pain.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor