Compound Summary


  Compound Information

药名:

Cepharanone A

别名:

Aristolactam II; 4-27-00-06583 (Beilstein Handbook Reference); BRN 0260559; CCRIS 2577; 55610-00-9; Benzo(f)-1,3-benzodioxolo(6,5,4-cd)indol-5(6H)-one; aristolactam ii

分子式:

C16H9NO3

Smiles:

C1OC2=C(O1)C3=C4C(=C2)C(=O)NC4=CC5=CC=CC=C53

成分:

HBIN020122; HBIN016775

OB_score:

20.20831

CAS_id:

55610-00-9

SymMap_id:

SMIT08503

TCMID_id:

1699

TCMSP_id:

MOL006976

PubChem_id:

148745


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004385 Fructus Aristolochiae 马兜铃 To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine./Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema.
TCMBANKHE004227/XU-506 Aristolochia manshuriensis 关木通|木通马兜铃 云南省红河州金平县 To clear heart fire, disinhibit urine, free menstruation and milk./Mouth sore, tongue sores, vexation and reddish urine, edema, heat strangury with inhibited pain, leukorrhea, amenorrhea and scant milk, damp-heat impediment pain.
TCMBANKHE007928 白药子 Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1