Compound Summary


  Compound Information

药名:

Micheline B

别名:

CCRIS 1549; Oxoushinsunin; C09567; 475-75-2; 8H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one; Spermatheridin; NCI60_001798; MEGxp0_001521; BRN 0273167; Spermatheridine; Noraporphin-7-one, 4,5,6,6a-tetradehydro-1,2-(methylenedioxy)-; NSC93681; NSC215254; Liriodenine; Oxoushinsunine; NSC 215254; 8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one; Ushinsunine, oxo-; NORAPORPHIN-7-ONE, 4,5,6,6a-TETRAHYDRO-1,2-(METHYLENEDIOXY)-; 8H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one (9CI); AIDS-008761; AIDS008761; NCI60_042088; NSC 93681; 4-27-00-06585 (Beilstein Handbook Reference)

分子式:

C17H9NO3

Smiles:

C1OC2=C(O1)C3=C4C(=C2)C=CN=C4C(=O)C5=CC=CC=C53

成分:

HBIN035497; HBIN038467; HBIN033393

OB_score:

14.825522

CAS_id:

475-75-2

SymMap_id:

SMIT06176; SMIT16321; SMIT18849

TCMID_id:

12911; 25391

TCMSP_id:

MOL004217

PubChem_id:

10144


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000810 Radix Zanthoxyli 两面针 To promote the flow of qi, relieve pain, to eliminate blood stasis, to promote blood circulation and dispel wind./Treatment of traumatic injury, rheumatic arthralgia, stomach-ache, teethache, bitten by venomous snake, applied for burn caused by hot liquid or fire.
TCMBANKHE002149 楮实子
TCMBANKHE002277 荷花
TCMBANKHE002732 蚕沙 1. Treatment of damp-heat obstruction syndrome. Silkworm excrement (Cansha) is used with Tetrandra root (Fangji), Coix seed (Yiyiren) and Talc (Huashi) in the formula Xuanbi Tang .2. Eczema. The decoction of the herb is used for external washing. 3. Treat
TCMBANKHE003066 Artabotrys uncinatus
TCMBANKHE003188 Stephania dinklagei
TCMBANKHE003744 Rhizoma Atractylodis macrocephalae 白术 To invigorate the function of the spleen and replenish qi, to eliminate damp by causing diuresis, to arrest excesssive perspiration, and to prevent miscarriage./Spleen qi vacuity, fatigue hypodynamia, reduced food intake with abdominal distention, sloppy stool, water-rheum collecting internally, inhibited urination, edema, phlegm-rheum dizziness, damp impediment, qi vacuity, spontaneous sweating, stirring fetus in pregnancy.
TCMBANKHE004086 Plumula Nelumbinis 莲子心 To remove heat from the heart and calm the nerves, to restore the coordination between the heart and the kidney, to check emission, and to arrest bleeding./Heat entering pericardium, clouded spirit with delirious speech, non-interaction of heart and kidney, insomnia and emission, blood ejection due to blood heat, hypertension.
TCMBANKHE004121 Radix Stemoe 百部 1. To moisten the lungs and stop cough; 2. To kill lice and parasites/Wind-cold cough, pertussis, tuberculosis, senile cough and asthma, ascariasis, oxyuria disease, scab and lichen, eczema, cootie.
TCMBANKHE004159 Radix Linderae 乌药 1. To regulate qi and stop pain; 2. To warm the kidneys and dispel cold/Distending pain in chest and abdomen, qi counterflow with rapid asthma, bladder vacuity cold, enuresis and frequent urination, mounting qi , dysmenorrhea.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE006226 Michelia alba 白兰花 To transform damp, move qi , relieve cough./Oppression in chest and abdomen distention, summerheat stroke, cough, prostatitis, Vaginal discharge.
TCMBANKHE004522 Rhizoma Corydalis 延胡索 1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls.
TCMBANKHE004543 Zanthoxylum cuspidatum 花椒簕 To quicken blood, dissipate stasis, relieve pain./Stasis stagnation pain in stomach duct and abdomen, knocks and falls.
TCMBANKHE004608 Magnolia grandiflora 荷花玉兰 To dispel wind and dissipate cold, move qi and relieve pain./Externally contracted wind-cold, headache and nasal congestion, distending pain in stomach duct, vomiting and diarrhea, hypertension, tuberculosis.
TCMBANKHE004771 Magnolia obovata 日本厚朴
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE005020 Annona reticulata 牛心番荔枝 To clear heat and check dysentery, expel worms./Heat toxin dysentery, intestinal parasitic disease.
TCMBANKHE005024 Liriodendron tulipifera 北美鹅掌楸 To dispel wind and eliminate damp, dissipate cold and relieve cough./Wind-damp impediment pain, wind-cold cough.
TCMBANKHE007157 Magnolia coco 夜合花 To move qi and dissipate stasis, relieve cough, check discharge./Liver depression and qi pain, knocks and falls, concretion and conglomeration, Vaginal discharge.
TCMBANKHE007483 Annona squamosa 番荔枝 To supplement stomach and spleen, clear heat and resolve toxin, kill worms./Malign sore and swelling toxin, intestinal parasitic disease.
TCMBANKHE005575 Tsoongiodendron odorum 观光木
TCMBANKHE006026 Goniothalamus amuyon 台湾哥纳香
TCMBANKHE007487 Fissistigma glaucescens [Syn. Melodorum glaucescens] 白叶瓜馥木 To dispel wind-damp, free menstruation and quicken blood, stanch bleeding./Wind-damp impediment pain, menstrual disorder, knocks and falls, fracture, bleeding due to external injury.
TCMBANKHE006185/XU-445 Artabotrys hexapetalus [Syn. Annona hexapetalus]|Artabotrys hexapetalus 鹰爪|鹰爪花 广西省百色市田林县浪平镇 To interrupt malaria./Malaria.
TCMBANKHE005257/YEM-104 Folium Nelumbinis|Nelumbo nucifera Gaertn. 荷叶|莲 云南民族药物志:第一卷 To relieve summer-heat, to invigorate the spleen function of the spleen and arrest bleeding by reducing heat in blood./Summerheat-heat vexation and thirst, summerheat-damp diarrhea, spleen vacuity diarrhea, blood heat, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE006652/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 莲子|莲 云南民族药物志:第一卷 To supplement spleen and check diarrhea, boost kidney and secure essence, nourish heart and quiet spirit./Chronic diarrhea, inappetence, emission, restlessness, fright palpitation, insomnia, flooding and spotting, excessive leukorrhea. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE003964/YEM-214/XU-446 Zanthoxylum nitidum|Zanthoxylum nitidum (Roxb.)DC 入地金牛|两面针 两面针 云南民族药物志:第二卷|广东省廉江市石岭镇 To dispel wind and free network vessels, disperse swelling and relieve pain./Wind-damp bone pain, stomachache, toothache, throat impediment, scrofula, burns and scalds. 傣族/哈尼族
TCMBANKHE004249/YEM-671 Michelia champaca|Michelia champaca L. 黄缅桂 黄缅桂 云南民族药物志:第四卷 To dispel wind-damp, disinhibit throat./Wind-damp impediment pain, swelling pain in throat. 傣族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha