Compound Summary


  Compound Information

药名:

betulin

别名:

AKOS025402304; Ambotz473-98-3; betulin ; AC-7983; SCHEMBL9888462; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol; FVWJYYTZTCVBKE-MAIYTPNSSA-N; ; Trochol; 18211-63-7; C08618; Messagenin; 473-98-3; AIDS002710; B9757_SIGMA; ZINC03978650; Prestwick3_000990; Betulin; MEGxp0_001726; AI3-62999; BSPBio_001059; Lup-20(30)-ene-3beta,28-diol; C08631; Betulinol; ACon1_000091; AIDS-002710; Lup-20(29)-ene-3beta,28-diol; BPBio1_001165; Betuline; Lup-20(29)-ene-3,28-diol, (3beta)-; NSC 4644; (3.beta.)-Lup-20(29)-ene-3,28-diol; NSC692218; EINECS 207-475-5; Betulinic alcohol; ST5411404; Trochol

分子式:

C30H50O2

Smiles:

CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)CO

成分:

HBIN018374; HBIN047242

OB_score:

15.479966

CAS_id:

473-98-3; 18211-63-7

SymMap_id:

SMIT01296; SMIT03946

TCMID_id:

2331

TCMSP_id:

MOL001551

PubChem_id:

72326


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000845 semen zizphi spinosae 枣仁 Treatment of insomnia, dream-disturbed sleep, excessive sweating due to debility, thirst due to consumption of body fluid./The chief components are jujuboside A and B. 1. Intraperitoneal injection its decoction ( 2.5-5.0g/kg ) exerts sedative and hypnotic effects in rats. 2. Intravenous injection of its decoction exerts significant and proloned hypotensive effect in anesthetized dogs. 3. Occasionally causing heart block. 4. Inducing hysterospasm.
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001079 川槿皮
TCMBANKHE001502 Semen Ziziphi Spinosae Preparata 炒枣仁 Treatment of insomnia, dream-disturbed sleep, excessive sweating due to debility, thirst due to consumption of body fluid./The chief components are jujuboside A and B. 1. Intraperitoneal injection its decoction ( 2.5-5.0g/kg ) exerts sedative and hypnotic effects in rats. 2. Intravenous injection of its decoction exerts significant and proloned hypotensive effect in anesthetized dogs. 3. Occasionally causing heart block. 4. Inducing hysterospasm.
TCMBANKHE001729 Cacumen Tamaricis 西河柳 To induce diaphoresis and dispel wind and to promote eruption./1. Bacteriostatic.2. Antipyretic.
TCMBANKHE002149 楮实子
TCMBANKHE002206 罗布麻叶
TCMBANKHE002552 零陵香
TCMBANKHE002993 灯台叶
TCMBANKHE003222 Folium Viticis Negundo 牡荆叶 To counteract toxicity, and to induce expectoration, relieve cough and asthma./1. Oral administration of its eemulsion (0.52-1.73g.kg) exerts a strong expectorant effect in mice.2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.3. Increasing the hypnotic effect of pentobarital sodium in mice.
TCMBANKHE003431 Valeriana laxiflora
TCMBANKHE003859 南五味子
TCMBANKHE007615 Rhizoma Sparganii 三棱 To eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain./Concretion conglomeration accumulation and gathering, qi-blood stagnation, pain in heart and abdomen, distending pain in rib-side, amenorrhea, postpartum blood stasis abdominal pain, knocks and falls, swelling of sores.
TCMBANKHE003967 Radix Platycodi 桔梗 To relieve cought, to soothe sore throat, and to promote expectoration and discharge of pus./Cough with profuse phlegm, swelling pain in throat, pulmonary welling abscess with hacking of pus and blood, fullness in chest and rib-side pain, dysentery, dribbling urinary block.
TCMBANKHE003986 苦丁茶 Common cold, summerheat stroke with fever, jaundice, acute gastroenteritis, bacillary dysentery, sore and boil.
TCMBANKHE004011 Fructus Syzygii 葡萄
TCMBANKHE005729 Semen Euphorbiae 千金子 To cause drastic purgation for treating edema, and eliminate blood stasis for treating masses./Edema, phlegm-rheum, accumulation and distention-fullness, urinary and fecal stoppage, amenorrhea due to blood stasis, intractable impediment, wart.
TCMBANKHE004707 Radix Paeoniae Rubra; Lignum Paeoniae Rubra 赤芍 To remove heat from blood, to eliminate blood stasis, and to relieve pain./1. Paeoniflorin, one of its active components, has a strong antispastic effect and also analgesic, sedative, anticonvulsive, antibacterial and anti-imflammatory effects. 2. Dilating blood vessels, increasing coronary flow and improving myocardial oxygen supply. 3. Inhibiting platelets aggregation.
TCMBANKHE004385 Fructus Aristolochiae 马兜铃 To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine./Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema.
TCMBANKHE004516 Sorbaria arborea 高丛珍珠梅 See Sorbaria sorbifolia ./See Sorbaria sorbifolia .
TCMBANKHE006369 Betula platyphylla 红桦皮 See Betula platyphylla./See Betula platyphylla.
TCMBANKHE004612 Semen Ziziphi Spinosae 酸枣仁 To replenish the liver, to cause tranquilizations to arrest excessive perspiration, and to promote the production of body fluid./Neurasthenia, vacuity vexation and insomnia, fright palpitation, arrhythmia, frequent dreaming, vacuity and profuse sweating, fluid damage and thirst.
TCMBANKHE004613 flos Sophorae 槐花 To arrest bleeding by reducing heat in blood, and to quench excess fire in the liver./1. Its component rutin decreases capillay permeability. 2. Lowering blood pressure transiently in anesthetized dog. 3. Inhibiting the growth of various dermatomyces.
TCMBANKHE004636 Fructus Zizyphi Jujubae 大枣 To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE004907 连钱草 Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE005058 Diospyros ebenum 乌木屑 To resolve toxin./Cholera with vomiting.
TCMBANKHE009130 Radix Platycodi 白桔梗 Treatment of cough with much phlegm, sore throat, hoarseness of voice, lung abscess with purulent expectoration, absecess difficult to burst after suppuration./1. Small dosage of platycodoside, one of its active components, can increase secretion of respiratory tract and promote expectoration.2. Platycodoside may also serve as a sedative, an analgesic and an antipyretic.3. Its decoction inhibits the growth of Staphylococcus aureus and Bacillus typhoid in vitro.
TCMBANKHE005252 枳椇子 Drunkenness, vexation and thirst, vomiting, inhibited urine and stool.
TCMBANKHE007295 Radix Aucklandiae 木香 To relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. /Distending pain in chest and stomach duct, diarrhea and tenesmus, non-digestion of food accumu lation, no thought of food and drink.
TCMBANKHE006738 Anemone raddeana 多被银莲花(两头尖) To dispel wind-damp, dissipate cold and relieve pain, disperse swollen welling abscess./Wind-cold-damp impediment, hypertonicity of limbs, aching pain in joints, swelling pain of welling abscess and sore.
TCMBANKHE008398 Acacia mellifera 具蜜金合欢;聚醚金合欢
TCMBANKHE005842 Vladimiria souliei [Syn. Jurinea souliei] 川木香 To move qi and relieve pain./Distending pain in stomach duct, rumbling intestines and diarrhea, tenesmus, liver gallbladder pain.
TCMBANKHE006021 Semen Sesami Nigrum 黑芝麻 To tonify the liver and the kidney, to replenish vital essence and blood, and to relax the bowels./Dizziness, tinnitus and deafness, premature graying in beard and hair, hair loss during convalescence, intestinal dry and constipation.
TCMBANKHE009131 Radix Platycodi 苦桔梗 Treatment of cough with much phlegm, sore throat, hoarseness of voice, lung abscess with purulent expectoration, absecess difficult to burst after suppuration./1. Small dosage of platycodoside, one of its active components, can increase secretion of respiratory tract and promote expectoration.2. Platycodoside may also serve as a sedative, an analgesic and an antipyretic.3. Its decoction inhibits the growth of Staphylococcus aureus and Bacillus typhoid in vitro.
TCMBANKHE008776 Betula platyphylla var. japonica 桦木皮 To clear heat and disinhibit damp, relieve cough and dispel phlegm, resolve toxin and disperse swelling./Pneumonia, dysentery, diarrhea, jaundice, nephritis, urinary tract infection, chronic trachitis, acute tonsillitis, periodontitis, acute mastitis, swollen boil, itchy papules, scalds.
TCMBANKHE008697 Caulis Aristolochiae seu Clematis 木通 1. To promote water metabolism and relieve abnormal urination; 2. To clear heat and promote lactation/Acute urethritis, short voidings of reddish urine, strangury-turbidity, edema, nephritis with edema, galactostasis, heat vexation in chest, throat pain, mouth sore, tongue sores, wind-damp impediment pain, galactostasis, amenorrhea, dysmenorrhea.
TCMBANKHE006566 Cortex Moutan 牡丹皮 To remove heat from blood, to activate blood circulation and eliminate blood stasis./Appendicitis, dysentery, hypertension, allergic rhinitis, warm heat disease with fever, macular eruption, blood ejection, spontaneous external bleeding, steaming bone tidal fever due to yin vacuity, amenorrhea due to blood stasis, dysmenorrhea, concretion and conglomeration, swelling toxin of welling abscess and sore, painful wound from knocks and falls, wind-damp-heat impediment.
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE006908 Hypoestes purpurea 枪刀药 To clear lung and relieve cough, cool blood and stanch bleeding, dissipate stasis and resolve toxin./Lung heat cough, hemoptysis, blood ejection, spontaneous external bleeding, flooding and spotting, jaundice, diarrhea, stasis swelling from knocks and falls, bleeding knife wound, fracture.
TCMBANKHE008310 Cortex Eucommiae 杜仲 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.
TCMBANKHE007131/XU-525 Rhodomyrtus tomentosa 桃金娘 广西省北海市银海区福成镇 To nourish blood and stanch bleeding, astringe intestines and secure essence./Blood vacuity and general weakness, blood ejection, nosebleed(epistaxis), taxation damage hemoptysis, hematochezia, flooding and spotting, emission, vaginal discharge, dysentery, prolapse of rectum, scalds, bleeding due to external injury.
TCMBANKHE007730 Fructus Meliae Toosendan 川楝子 To relieve pain by smoothing the flow of the liver qi and to repel worms./Chest and rib-side pain, distending pain in stomach duct, mounting qi , abdominal pain due to worm accumulation.
TCMBANKHE008512 radix Peucedani 前胡 To dispel wind and remove heat, and to relieve cough and resolve phlegm ./Cough, externally contracted wind-heat, lung heat phlegm depression, cough and asthma with abundant phlegm, sticky phlegm, retching counterflow and reduced food intake, fullness and oppression in chest and diaphragm.
TCMBANKHE008341 Fructus Zizyphi Jujubae 大枣 To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE005860/YNS-115 Phlogacanthus curviflorus|Phlogacanthus curviflorus(Wall.)Ness 火焰花 火焰花叶 云南药材标准:第三册 顽疟不解,发冷发热,头晕头痛,胸腹痞满。|To clear heat and resolve toxin, interrupt malaria./Heat toxin swollen welling abscess, malaria.
TCMBANKHE005411/XU-794 Phyllanthus flexuosus 落萼叶下珠 广西省崇左市大新县 To clear heat and resolve toxin, dispel wind and eliminate damp./Allergic dermatitis, infantile night crying, snake bite, wind-damp.
TCMBANKHE005271/YNS-173/XU-59 Rosmarinus officinalis|Rosmarinus officinalis Linn.|Rosmarinus officinalis L. 迷迭香 迷迭香 云南药材标准:第四册|云南省昆明市盘龙区 祛风解表,健脾和胃,理气止痛。用于外感头痛,头风痛, 饮食积滞,脘腹胀痛|To effuse sweat, fortify spleen, quiet spirit, relieve pain./Headache, prevention of hair loss in early stage.
TCMBANKHE006421/YEM-1037/XU-804 Trichosanthes kirilowii Maxim.|Trichosanthes kirilowii 瓜蒌|栝楼 天花粉 云南民族药物志:第五卷|云南省昭通市盐津县 Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore. 苗族/彝族
TCMBANKHE005628/YEM-121 Fructus Chaenomelis|Chaenomeles speciosa (Sweet) Nakai 木瓜|皱皮木瓜 木瓜 云南民族药物志:第一卷 To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema. 傣族/景颇族/苗族/彝族/藏族
TCMBANKHE005302/YNS-291/YEM-267/XU-217 Diospyros kaki|Diospyros kaki Thumb.var. silvestris Makino|Diospyros kaki Thunb.|Diospyros kaki var. silvestris 柿叶|野柿|柿 野柿根|柿 云南药材标准:第五册|云南民族药物志:第二卷|广西省桂林市荔浦县蒲芦乡天河瀑布景区外 调补四塔,补土健胃,增性强身,清火解毒,用于气虚喘咳,神疲乏力,不思饮食,性欲减退,早衰,胆汁病()|To relieve cough and settle asthma, engender liquid and allay thirst, quicken blood and stanch bleeding./Cough and asthma, lung qi distention, internal bleeding. 傣族/哈尼族/傈僳族/苗族/水族/佤族/彝族
TCMBANKHE008167/YEM-39/XU-672 Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides 杜仲 杜仲 云南民族药物志:第一卷|贵州省岑巩县平庄镇师兆村 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE006320/YNS-277/YEM-464/XU-68 Sambucus williamsii|Sambucus williamsii Hance 接骨木 续骨木|接骨木 云南药材标准:第二册|云南民族药物志:第三卷|云南省昆明市盘龙区 接骨续筋,消肿止痛。用于骨折,跌倒损伤,风湿疼痛,腰痛,肾病水肿,皮肤瘙痒|To dispel wind and disinhibit damp, quicken blood, stanch bleeding./Wind-damp impediment pain, pain wind, osteoarthritis, acute nephritis, chronic nephritis, wind papules, knocks and falls, swelling pain from fracture, bleeding due to external injury. 哈尼族/傈僳族/苗族/水族/壮族
TCMBANKHE004583/YEM-60/XU-35 Juglans regia|Juglans regia L. 胡桃仁|胡桃|核桃树根 核桃 云南民族药物志:第一卷|云南省楚雄彝族自治州永仁县永仁古镇农贸市场 To supplement kidney and boost essence, warm lung and settle asthma, moisten intestines and free stool./Enduring cough and asthma, bronchitis, lumbago and limp leg, frequent urination, enuresis, impotence, emission, intestinal dry and constipation, stone strangury, sores and scrofula. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE001443/YEM-631 Rhizoma Pinelliae Preparata|Pinellia ternata(Thunb.)Breit. 制半夏|半夏 半夏 云南民族药物志:第四卷 Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hystericus. Rhizoma Pineliae (processed with ginger) is often used for relieving nausea and vomiting. Rhizoma pinelliae (Proccessed with alum) for removing damp and phlegm. Rhizoma Pinelliae (unproccessed) is used externally for boils, sores and lymphadenitis./Treatment of cough and asthma with much phlegm, dizziness and palpitation due to retention of phlegm and fluid, vertigo caused by wind-phlegm, headache with cold extremities due to attack of phlegm , stuffiness in the chest and the epigastrium, globus hys 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/彝族/藏族/壮族
TCMBANKHE005739/YEM-637 Vicia faba|Vicia faba L. 蚕豆 蚕豆 云南民族药物志:第四卷 To fortify spleen and disinhibit water, resolve toxin and disperse swelling./Diaphragm food, edema, sore toxin. 傣族/佤族/彝族
TCMBANKHE004735/YEM-889/XU-572/XU-836 Diospyros lotus|Diospyros lotus L. 君迁子 君迁子 云南民族药物志:第五卷|云南省曲靖市会泽县 To clear heat, allay thirst./Heat vexation, diabetes mellitus. 傈僳族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族
TCMBANKHE003869/YEM-999/XU-341 Folium Isatidis|Isatis indigotica Fort.|Isatis indigotica 板蓝根(大青叶)|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To clear heat and toxic materials, cool blood and eliminate eruption./Acute parotitis, encephalitis, hepatitis, lung abscess, acute gastroenteritis, infection of upper respiratory tract, warm evil in construction, ardent fever with clouded spirit, macular eruption and papules, jaundice, heat dysentery, epidemic parotitis, throat impediment, erysipelas, swollen welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000026 Obesity disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 28027595
TCMBANKDI000085 Inflammation phenotype Pathological Conditions, Signs and Symptoms 28027595
TCMBANKDI002163 Neoplasms, Experimental phenotype Neoplasms 28027595
TCMBANKDI003353 Carcinogenesis phenotype Pathological Conditions, Signs and Symptoms; Neoplasms 28027595
TCMBANKDI015496 Liver neoplasms group Digestive System Diseases; Neoplasms 28027595

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000051 IL1B IL-1; IL1-BETA; IL1F2; IL1beta interleukin 1 beta
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE001027 STK11 LKB1; PJS; hLKB1 serine/threonine kinase 11
TCMBANKGE001112 PRKAB1 AMPK; HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE001135 SREBF1 SREBP1; bHLHd1 sterol regulatory element binding transcription factor 1
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor