Compound Summary


  Compound Information

药名:

isobavachin

分子式:

C20H20O4

Smiles:

CC(=CCC1=C(C=CC2=C1OC(CC2=O)C3=CC=C(C=C3)O)O)C

成分:

HBIN030472

OB_score:

54.442743

SymMap_id:

SMIT03048

TCMID_id:

11245

TCMSP_id:

MOL000448

PubChem_id:

11609510


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE004471 Humulus lupulus 啤酒花 To fortify stomach and disperse food, disinhibit urine and quiet spirit, eliminate inflammation./Indigestion, abdominal distention, edema, cystitis, tuberculosis, cough, insomnia, leprosy.
TCMBANKHE005525 Macaranga conifera 针叶血桐
TCMBANKHE006604 Sophora tomentosa 岭南槐树
TCMBANKHE006348 Dioscorea rotundata [Syn. Dioscorea cayenensis ] 圆薯蓣
TCMBANKHE008358 Cudrania cochinchinensis 狗脊 To dispel wind and free network vessels, clear heat and remove damp, resolve toxin and disperse swelling./Wind-damp impediment pain, knocks and falls, jaundice, parotitis, phthisis, gastric ulcer, duodenal ulcer, strangury-turbidity, tympanites, menstrual block, taxation damage and coughing of blood, clove sore and swollen welling abscess.
TCMBANKHE006236/XU-723 Psoralea corylifolia 补骨脂 云南省西双版纳勐腊县 To supplement kidney and invigorate yang , accept qi and calm asthma, warm spleen and check diarrhea./Fracture, osteomalacia, osteoporosis, kidney yang vacuity, cold pain in lumbus and knees, impotence and emission, frequent urination, enuresis, kidney qi insecurity, vacuity asthma, spleen-kidney vacuity, chronic diarrhea, white patch wind, alopecia areata, psoriasis.
TCMBANKHE008315 Cortex erythrie 海桐皮 1. To dispel wind and dampness; 2. To clear the meridians/Wind-damp impediment, pain in lumbus and knees, scab sore, lichen, eczema.
TCMBANKHE009076 Sophora moorcroftiana 砂生槐 To clear heat and dry damp, resolve toxin./Damp-heat jaundice, diphtheria, nipple moth.
TCMBANKHE007797 Sophora moorcroftiana 沙身槐;砂生槐 To clear heat and dry damp, resolve toxin./Damp-heat jaundice, diphtheria, nipple moth.
TCMBANKHE007793 Tamus communis 浆果薯蓣
TCMBANKHE002976/XU-723 Fructus Psoraleae Corylifoliae|Psoralea corylifolia 破故纸|补骨脂 云南省西双版纳勐腊县 Treatment of impotence, seminal emission, enuresis, frequent urination, aching of the loins and knees with cold sensation, asthma in deficiency syndromes of the kidney, diarrhea occurring before dawn daily. External use for vitiligo and alpecia areata./1. Corylifolinin ( isobavachalcone ) dilates coronary artery significantly. 2. Promoting phagocytosis of macrophage. 3. Exciting the intestinal smooth muscles in vivo or in vitro, and relaxing the uterus of guinea-pigs in vitro.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1