Compound Summary

  Compound Information

TCMBANKIN058801

药名:	Tecomin
别名:	KBio1_000594; NSC 11905; NCGC00094931-01; Spectrum3_000768; Cancer Chemother Rep (part 2) 4: 11 (1974); Spectrum5_001873; Lapachol Wood; NCI60_000457; 1,4-Naphthalenedione, 2-hydroxy-3-(3-methyl-2-butenyl)- (9CI); C.I. Natural Yellow 16; InChI=1/C15H14O3/c1-9(2)7-8-12-13(16)10-5-3-4-6-11(10)14(17)15(12)18/h3-7,18H,8H2,1-2H; BSPBio_002416; SPECTRUM1501204; Bethabarra Wood; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; SPBio_001341; IDI1_000594; Lapachic acid; Ipe-tobacco Wood; 4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione; Tecomin (VAN); NCI60_000587; AIDS-010570; NSC-11905; Taiguic acid; Lapachol; ZINC00056450; Spectrum2_001451; 142905_ALDRICH; WLN: L66 BV EVJ CQ D2UY1&1; KBio3_001636; EINECS 201-563-7; 1,4-Naphthalenedione, 2-hydroxy-3-(3-methyl-2-butenyl)-; 84-79-7; NSC 629756; C.I. 75490; 4-hydroxy-3-(3-methylbut-2-enyl)-1,2-naphthoquinone; Greenhartin; CCRIS 745; Zlut prirodni 16 [Czech]; 1,4-Naphthoquinone, 2-hydroxy-3-(3-methyl-2-butenyl)-; 2-Hydroxy-3-(3-methylbut-2-enyl)-1,4-naphthoquinone; NSC11905; C10366; STOCK1N-11398; Oprea1_717083; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione; 4-08-00-02487 (Beilstein Handbook Reference); NCGC00094931-02; Taigu Wood; SDCCGMLS-0066666.P001; DivK1c_000594; NINDS_000594; AIDS010570; Surinam Greenheart Wood; Natural Yellow- 16; BRN 2051889; NSC629756; NCIMech_000076; Greenharten; lapachol
分子式:	C15H14O3
Smiles:	CC(=CCC1=C(C2=CC=CC=C2C(=O)C1=O)O)C
成分:	HBIN045827;HBIN032647
OB_score:	65.409375
CAS_id:	84-79-7
SymMap_id:	SMIT13765
TCMID_id:	12496
TCMSP_id:	MOL013067
PubChem_id:	3884

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002355	Newbouldia laevis
TCMBANKHE004507	Kigelia pinnata	吊灯树
TCMBANKHE005168		辛夷			Wind-cold common cold, headache, nasal congestion and runny nose, nasitis, nasosinusitis.
TCMBANKHE007684	Hibiscus tiliaceus	黄槿			To clear lung and relieve cough, resolve toxin and disperse swelling./Lung heat cough, swelling pain of sore and boil, cassava poisoning.
TCMBANKHE008359	Semen Oroxyli	木蝴蝶			To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000009

Glioma

disease

Neoplasms

27852319

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001467	LTA4H	-	leukotriene A4 hydrolase
TCMBANKGE001755	MAOB	-	monoamine oxidase B
TCMBANKGE003625	SLC6A4	5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT	solute carrier family 6 member 4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE013299	F3	CD142; TF; TFA	coagulation factor III, tissue factor
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1