Compound Summary
Compound Information
药名: | ginsenoside- Rg1 |
别名: | ginsenoside-rg1;(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(1S)-1,5-dimethyl-1-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]hex-4-enyl]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H; (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a; (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(1S)-1,5-dimethyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-hex-4-enyl]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclop; (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-hept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[; C08946; (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(1S)-1,5-dimethyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hex-4-enyl]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-; 22427-39-0; sanchinoside rg1; Sanchinoside C1 |
分子式: | C42H72O14 |
Smiles: | CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C |
成分: | HBIN027747;HBIN042946;HBIN042945 |
OB_score: | 9.028882 |
CAS_id: | 22427-39-0 |
SymMap_id: | SMIT12311;SMIT18944;SMIT07116 |
TCMID_id: | 25710 |
TCMSP_id: | MOL011401;MOL005341 |
PubChem_id: | 441923 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE004260 | Radix Ginseng | 人参 | To reinforce the vital energy, to remedy collapse and restore the normal pulse, to benefit the spleen and lung, to promote the production of body fluid, and to calm the nerves./Qi vacuity and verging on desertion, cold limbs and faint pulse, reduced food intake due to spleen vacuity, cough and asthma due to lung vacuity, fluid damage and thirst, diabetes mellitus due to internal heat, enduring illness qi vacuity, fright palpitation and insomnia, impotence, uterus cold, cardiac failure. | |||
| TCMBANKHE001010 | 竹节参 | |||||
| TCMBANKHE001345 | Radix Ginseng Rubra | 红参 | Replenish vital essence, promote blood circualtion and relieve collapse. To reinforce qi and to stanch bleeding./Treatment of collpase tendency due to asthenia, cool limbs and weak pulse. Qi cannot control blood, uterine bleeding, cardiac failure and cardiogenic shock. | |||
| TCMBANKHE004248 | Radix Pacis quinquefolii | 西洋参 | 1. To replenish qi and promote body fluids; 2. To nourish yin and clear heat/Qi vacuity, yin depletion and effulgent fire, cough and asthma with phlegm-blood, vacuity heat and vexation fatigue, diabetes mellitus due to internal heat, thirst with dry throat. | |||
| TCMBANKHE009030 | Resi myrrhae;Myrrha | 没药 | 1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall. | |||
| TCMBANKHE007443 | Folium Ginseng | 人参叶 | To nourish qi and lung, expel summer-heat, to promote fluid secretion./Summerheat-heat and thirst, febrile diseases fluid damage, stomach yin insufficiency, diabetes mellitus, dry cough due to lung dryness, vacuity-fire toothache. | |||
| TCMBANKHE004506/YEM-137 | Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. | 三七 | 三七 | 云南民族药物志：第一卷 | To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. | 彝族 |
| TCMBANKHE004643/YEM-590/XU-716 | Folium Mori|Morus alba L.|Morus alba | 桑叶|桑 | 桑叶 | 云南民族药物志：第三卷|云南省昭通市盐津县 | To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. | 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000236 | BDNF | ANON2; BULN2 | brain derived neurotrophic factor |
| TCMBANKGE000737 | PGR | NR3C3; PR | progesterone receptor |
| TCMBANKGE000965 | CHRNA7 | CHRNA7-2; NACHRA7 | cholinergic receptor nicotinic alpha 7 subunit |
| TCMBANKGE001118 | MMP9 | CLG4B; GELB; MANDP2; MMP-9 | matrix metallopeptidase 9 |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE001148 | VEGFA | MVCD1; VEGF; VPF | vascular endothelial growth factor A |
| TCMBANKGE001197 | FOS | AP-1; C-FOS; p55 | Fos proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE002258 | HTR3C | - | 5-hydroxytryptamine receptor 3C |
| TCMBANKGE003242 | CHRNA6 | CHNRA6 | cholinergic receptor nicotinic alpha 6 subunit |
| TCMBANKGE003829 | CHRNB2 | EFNL3; nAChRB2 | cholinergic receptor nicotinic beta 2 subunit |
| TCMBANKGE004709 | HTR3D | 5HT3D | 5-hydroxytryptamine receptor 3D |
| TCMBANKGE005062 | CHRNB4 | - | cholinergic receptor nicotinic beta 4 subunit |
| TCMBANKGE005702 | CHRNA10 | - | cholinergic receptor nicotinic alpha 10 subunit |
| TCMBANKGE007564 | CHRNB1 | ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS | cholinergic receptor nicotinic beta 1 subunit |
| TCMBANKGE008700 | CHRNA2 | - | cholinergic receptor nicotinic alpha 2 subunit |
| TCMBANKGE009105 | CHRNB3 | - | cholinergic receptor nicotinic beta 3 subunit |
| TCMBANKGE009155 | CHRNA5 | LNCR2 | cholinergic receptor nicotinic alpha 5 subunit |
| TCMBANKGE009294 | HTR3A | 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 | 5-hydroxytryptamine receptor 3A |
| TCMBANKGE009628 | CHRNE | ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS | cholinergic receptor nicotinic epsilon subunit |
| TCMBANKGE010487 | CHRNA1 | ACHRA; ACHRD; CHRNA; CMS1A; CMS1B; CMS2A; FCCMS; SCCMS | cholinergic receptor nicotinic alpha 1 subunit |
| TCMBANKGE010739 | TFF1 | BCEI; D21S21; HP1.A; HPS2; pNR-2; pS2 | trefoil factor 1 |
| TCMBANKGE010862 | CHRND | ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS | cholinergic receptor nicotinic delta subunit |
| TCMBANKGE011186 | CHRNA3 | BAIPRCK; LNCR2; NACHRA3; PAOD2 | cholinergic receptor nicotinic alpha 3 subunit |
| TCMBANKGE011465 | HTR3B | 5-HT3B | 5-hydroxytryptamine receptor 3B |
| TCMBANKGE013367 | CHRNA9 | HSA243342; NACHRA9 | cholinergic receptor nicotinic alpha 9 subunit |
| TCMBANKGE013670 | HTR3E | 5-HT3-E; 5-HT3E; 5-HT3c1 | 5-hydroxytryptamine receptor 3E |
| TCMBANKGE014385 | CHRNA4 | BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4 | cholinergic receptor nicotinic alpha 4 subunit |
| TCMBANKGE014586 | CHRNG | ACHRG | cholinergic receptor nicotinic gamma subunit |
| TCMBANKGE015129 | CHRFAM7A | CHRNA7; CHRNA7-DR1; D-10; NACHRA7 | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion |
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