Compound Summary


  Compound Information

药名:

Hypnon

别名:

1-Phenylethanone; InChI=1/C8H8O/c1-7(9)8-5-3-2-4-6-8/h2-6H,1H; C07113; Acetylbenzene; ZINC00896628; Ethanone, 1-phenyl-; Acetophenon; 00790_FLUKA; Ketone, methyl phenyl; WLN: 1VR; 442438_SUPELCO; Methyl phenyl ketone; Usaf ek-496; 42163_FLUKA; Ketone, methyl phenyl-; Benzoyl methide; AI3-00575; AIDS-017929; W200905_ALDRICH; FEMA Number 2009; RCRA waste number U004; FEMA No. 2009; Phenyl methyl ketone; NSC 7635; RCRA waste no. U004; NSC7635; A10701_ALDRICH; 98-86-2; CCRIS 1341; AC0; Acetophenone; ST5213401; EINECS 202-708-7; CHEBI:27632; Hypnone; 1-phenylethan-1-one; HSDB 969; Benzoylmethide; 1-Phenyl-1-ethanone; Benzene, acetyl-; c0117; AIDS017929; Acetofenon [Czech]; Acetylbenzol;1-(Phenyl-D5)-Ethanon; NSC 98542-d5; 1-[(2,3,4,5,6-(2)H?)PHENYL]ETHANONE; Acetophenone-(phenyl-d5), 99 atom % D; ACM28077647; DTXSID70466417; Acetophenone-2',3',4',5',6'-d5; Acetophenon-d5; pentadeuterophenyl methyl ketone; FT-0661057; Acetylbenzene-d5; Hypnone-d5; MFCD00064446; 1-(Phenyl-d5)ethanone; 1-(2,3,4,5,6-pentadeuteriophenyl)ethanone; Acetophenone-2/',3/',4/',5/',6/'-d5; SCHEMBL1332185; Methyl (Phenyl-d5) Ketone; DE155; J-016964; 28077-64-7; 1-(Phenyl-d5)-1-ethanone; MolPort-003-929-975; NSC 7635-d5; (Phenyl-d5) Methyl Ketone; Acetophenone-(phenyl-d5); Acetophenone-d5; Acetophenone-2 inverted exclamation marka,3 inverted exclamation marka,4 inverted exclamation marka,5 inverted exclamation marka,6 inverted exclamation marka-d5; Hypnon-d5; 1-Feniletanone-d5; Acetophenone-(phenyl-d5) 99 atom % D; 1-Phenylethanone-d5; Acetophenone-2'3'4'5'6-d5;phenyl-ethanone;acetophenone;phenylethanone;1-phenylethanone

分子式:

C8H8O

Smiles:

CC(=O)C1=CC=CC=C1

成分:

HBIN029840;HBIN002985;HBIN014423;HBIN039511

OB_score:

48.19256

CAS_id:

98-86-2

SymMap_id:

SMIT03970;SMIT01248

TCMID_id:

115

TCMSP_id:

MOL001578

PubChem_id:

7410

DrugBank_id:

DB04619


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE001675 景天三七
TCMBANKHE002277 荷花
TCMBANKHE002552 零陵香
TCMBANKHE002879 Nux Prinsepiae 蕤仁 To nourish the liver and improve eyesight, and to dispel wind-heat./Treatment of conjuntivitis and blepharitis marginalis with impaired vision and photophobia.
TCMBANKHE003726 Cortex Cinmomi 肉桂 To supplement body fire, reinforce yang, and lead the fire back to the kidney, to dispel cold and relieve pain, and to activate blood circulation and stimulate menstrual discharge./Impotence, uterus cold, cold pain in lumbus and knees, kidney vacuity asthma, yang vacuity dizziness, red eyes and sore pharynx, cold pain in heart and abdomen, vacuity cold vomiting and diarrhea, cold mounting, running piglet, amenorrhea, dysmenorrhea.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003784 Radix Cynchi Paniculati 徐长卿 To relieve rheumatic conditions, and to arrest pain and itching./Rheumatic arthritis, toothache, lumbago, pain after operation, dysmenorrhea, mastitis, infection of skin, eczema, neurodermatitis, urticaria, infective dermatitis, zoster, wind-damp impediment pain, knocks and falls.
TCMBANKHE003940 Herba Elsholtziae;Haichow Elsholtzia;Mosla chinensis 香薷 1. To promote diaphoresis and release the exterior; 2. To resolve dampness and harmonize the spleen and stomach; 3. To promote water metabolism and release edema/Fever, aversion of cold, headache, absence of sweating, abdominal pain, vomiting and diarrhea, edema and inhibited urination, beriberi.
TCMBANKHE004172 Radix Bupleuri 柴胡 To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE008006 Urtica dioica 异株荨麻 See Urtica cannabina./See Urtica cannabina.
TCMBANKHE004258 Radix Angelicae sinensis 当归根 To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE004515 Hericium erinaceus 猴头菇 To benefit vital Qi, invigorate the spleen and nourish the stomach. For hypofunction of the spleen and stomach, peptic ulcer and chronic gastritis. Recently, also used for the cancers of erophagus, stomach and intestines./To benefit vital Qi, invigorate the spleen and nourish the stomach. For hypofunction of the spleen and stomach, peptic ulcer and chronic gastritis. Recently, also used for the cancers of erophagus, stomach and intestines.
TCMBANKHE008431 牡荆子
TCMBANKHE006660 Ramulus Cinmomi 桂枝 To induce perspiration, to warm the channels and stimulate menstrual discharge, to reinforce yang, to relieve palpitation, and to promote the descending of qi./Wind-cold exterior syndrome, cold-damp impediment pain, reversal cold of limbs, amenorrhea and dysmenorrhea, concretion and conglomeration, chest impediment, palpitation, phlegm-rheum, inhibited urination.
TCMBANKHE004912 Flos Caryophylli 丁香 To warm the spleen and stomach, to regulate the adverse flow of the stomach qi, and to restore the kidney yang./Stomach cold with retching counterflow, hiccough, cold pain in stomach duct and abdomen, reduced food intake and diarrhea, kidney vacuity impotence, vacuity cold in lumbus and knees, yin flat abscess.
TCMBANKHE004973 Herba Ephedrae 麻黄 To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.
TCMBANKHE005497 Rhizoma Belamcandae 射干 To remove toxic heat, eliminate phlegm, and soothe the sore throat./Heat toxin and phlegm-fire stasis, swelling pain in throat, cough and asthma.
TCMBANKHE005549 Styrax 苏合香 1. To open the orifices and clear the mind; 2. To stop pain/Wind stroke with phlegm reversal, sudden clouding collapse, cold pain in chest and abdomen, fright epilepsy, warm disease.
TCMBANKHE005581 Herba Equiseti Hiemalis 木贼 To dispel wind-heat and to remove nebula./Wind-heat red eye, tearing in wind, eye screen.
TCMBANKHE006102 Equisetum hyemale 木贼 To dispel wind-heat and to remove nebula./To dispel wind-heat and to remove nebula
TCMBANKHE006133 紫苏 Phlegm congestion and qi counterflow, cough and asthma, intestinal dry and constipation.
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE008361 荜茇 Cold pain in stomach duct and abdomen, vomiting, diarrhea, headache, toothache, deep-source nasal congestion, coronary heart disease, angina pectoris.
TCMBANKHE006598 Benzoinum 安息香 To restore consciousness. To activate the flow of qi and blood. To relieve pain./Sudden stroke and fulminant reversal, pain in heart and abdomen, postpartum blood dizziness, child fright epilepsy, wind impediment and lumbago.
TCMBANKHE007155 Radix Scrophulariae 玄参; 元参 To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity. Treatment of febrile diseases with impairment of yin manifested by deep red tongue and dire thirst, or with eruptions, constipation due to impairment of body fluid, phthisis with cough, conjunctivitis, sore throat, scrofula, diphtheria, boils and sores./Heat entering construction-blood, generalized fever, vexation and thirst, crimson tongue, macular eruption, steaming bone taxation cough, vacuity vexation and insomnia, fluid damage and constipation, dry eyes with clouded flowery vision, swelling pain in throat, scrofula with phlegm node, sore toxin of welling abscess and flat abscess. 1. Its alcoholic extract and its component methoxycinnamic acid can lower the typhoid vaccine-induced fever in rabbits.2. Its water or alcoholic infusion and decoction exert a mild hypotensive effect on anesthetized animals3. Lowering the level of blood sugar.4. Its infusion inhibits the growth of some dermatomyces.
TCMBANKHE009183 Populus balsamifera 脂杨
TCMBANKHE006664/YNS-181/XU-60/XU-236 Fructus Arctii lappae|Arctium lappa L.|Arctium lappa 牛蒡子;大力子|牛蒡 牛蒡根 云南药材标准:第二册|西藏昌都市洛隆县 祛风清热,解毒消肿,力气通便。用于咽喉肿痛,牙龈肿痛,咳嗽痰稠,腹胀便秘,消渴;黄白带下,干血痨,产后少乳,风毒面肿,大头风,疮疡肿痛|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin.
TCMBANKHE008288/YEM-108 Resina Liquidambaris|Liquidambar formosana Hance. 枫香脂|枫香树 路路通 云南民族药物志:第一卷 Treatment of traumatic injuries, swelling and pain of carbuncle and boil, spitting of blood, epistaxis and traumatic hemorrhage./Treatment of traumatic injuries, swelling and pain of carbuncle and boil, spitting of blood, epistaxis and traumatic hemorrhage. 彝族
TCMBANKHE004506/YEM-137 Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. 三七 三七 云南民族药物志:第一卷 To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. 彝族
TCMBANKHE006781/YEM-333 Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk. 防风 防风 云南民族药物志:第二卷 To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE005387/YNS-267/YEM-782 Elsholtzia bodinieri|Elsholtzia bodinieri Van. 凤尾茶|东紫苏 小山茶 |小山茶 云南药材标准:第一册|云南民族药物志:第四卷 发散解表,清热利湿。用于感冒,咽喉痛,头痛,扁桃腺炎,小儿口腔炎,牙痛,眼结膜炎,肝炎,消化不良|To dissipate exopathogen, rectify qi and harmonize stomach./Common cold, red swollen in throat, red eyes with gall, stomatitis, toothache, hepatitis, indigestion. 拉祜族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000646 DECR1 DECR; NADPH; SDR18C1 2,4-dienoyl-CoA reductase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001477 RDH8 PRRDH; SDR28C2 retinol dehydrogenase 8
TCMBANKGE001528 DHRS7B CGI-93; SDR32C1 dehydrogenase/reductase 7B
TCMBANKGE001692 RDH12 LCA13; RP53; SDR7C2 retinol dehydrogenase 12
TCMBANKGE002099 DHRS7C SDR32C2 dehydrogenase/reductase 7C
TCMBANKGE002555 HSD11B1 11-DH; 11-beta-HSD1; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1 hydroxysteroid 11-beta dehydrogenase 1
TCMBANKGE003092 HSD11B1L 11-DH3; 11-beta-HSD3; HSD1L; HSD3; SCDR10; SCDR10B; SDR26C2 hydroxysteroid 11-beta dehydrogenase 1 like
TCMBANKGE003649 RDH14 PAN2; SDR7C4 retinol dehydrogenase 14
TCMBANKGE005304 RDH10 SDR16C4 retinol dehydrogenase 10
TCMBANKGE005507 HPGD 15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1 15-hydroxyprostaglandin dehydrogenase
TCMBANKGE005781 CBR1 CBR; SDR21C1; hCBR1 carbonyl reductase 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006886 ADH1A ADH1 alcohol dehydrogenase 1A (class I), alpha polypeptide
TCMBANKGE006933 DHRS4L2 SDR25C3 dehydrogenase/reductase 4 like 2
TCMBANKGE007026 CBR4 SDR45C1 carbonyl reductase 4
TCMBANKGE008641 HSD17B13 HMFN0376; NIIL497; SCDR9; SDR16C3 hydroxysteroid 17-beta dehydrogenase 13
TCMBANKGE008718 PRSS3 MTG; PRSS4; T9; TRY3; TRY4 serine protease 3
TCMBANKGE009006 C2orf81 hCG40743 chromosome 2 open reading frame 81
TCMBANKGE009091 SDR16C5 EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2 short chain dehydrogenase/reductase family 16C member 5
TCMBANKGE009389 LYZ LYZF1; LZM lysozyme
TCMBANKGE009446 DHRS12 SDR40C1 dehydrogenase/reductase 12
TCMBANKGE010106 HSD17B11 17-BETA-HSD11; 17-BETA-HSDXI; 17BHSD11; DHRS8; PAN1B; RETSDR2; SDR16C2 hydroxysteroid 17-beta dehydrogenase 11
TCMBANKGE010124 DHRS1 SDR19C1 dehydrogenase/reductase 1
TCMBANKGE011011 DHRSX CXorf11; DHRS5X; DHRS5Y; DHRSXY; DHRSY; SDR46C1; SDR7C6 dehydrogenase/reductase X-linked
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011293 RDH11 ARSDR1; CGI82; HCBP12; MDT1; PSDR1; RALR1; RDJCSS; SCALD; SDR7C1 retinol dehydrogenase 11
TCMBANKGE011300 DHRS13 SDR7C5 dehydrogenase/reductase 13
TCMBANKGE011682 HSD17B1 17-beta-HSD; 20-alpha-HSD; E2DH; EDH17B2; EDHB17; HSD17; SDR28C1 hydroxysteroid 17-beta dehydrogenase 1
TCMBANKGE011927 CBR3 HEL-S-25; SDR21C2; hCBR3 carbonyl reductase 3
TCMBANKGE012486 BDH2 DHRS6; EFA6R; PRO20933; SDR15C1; UCPA-OR; UNQ6308 3-hydroxybutyrate dehydrogenase 2
TCMBANKGE012495 PECR DCRRP; HPDHASE; HSA250303; PVIARL; SDR29C1; TERP peroxisomal trans-2-enoyl-CoA reductase
TCMBANKGE012776 DECR2 PDCR; SDR17C1 2,4-dienoyl-CoA reductase 2
TCMBANKGE012786 RDH13 SDR7C3 retinol dehydrogenase 13
TCMBANKGE012862 DHRS4 CR; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2 dehydrogenase/reductase 4
TCMBANKGE013060 HSD17B8 D6S2245E; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1; dJ1033B10.9 hydroxysteroid 17-beta dehydrogenase 8
TCMBANKGE013304 HSDL2 C9orf99; SDR13C1 hydroxysteroid dehydrogenase like 2
TCMBANKGE014135 HSD17B14 DHRS10; SDR47C1; retSDR3 hydroxysteroid 17-beta dehydrogenase 14
TCMBANKGE014938 DHRS2 HEP27; SDR25C1 dehydrogenase/reductase 2