Compound Summary


  Compound Information

药名:

isomicropinic acid;sugiol

别名:

(4aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one; AC1NT0MY; 7-carbonyl-12-hydroxy-dehydroabietane; 1,1,4abeta-Trimethyl-6-hydroxy-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-9-one; SCHEMBL17407685

分子式:

C20H28O2

Smiles:

CC(C)C1=C(C=C2C(=C1)C(=O)CC3C2(CCCC3(C)C)C)O

成分:

HBIN030943;HBIN045115

OB_score:

36.113535

CAS_id:

511-05-7

SymMap_id:

SMIT00491

TCMID_id:

20449

TCMSP_id:

MOL002222

PubChem_id:

275529


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003717 fructus Capsici 辣椒 See Capsicum annuum.
TCMBANKHE003752 Radix Salviae liguliobae 丹参 To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE007677 Cephalotaxus wilsoniana 台湾粗榧
TCMBANKHE005903 Thuja standishii 日本香柏茎皮
TCMBANKHE006672 Cephalotaxus harringtonia var. drupacea 长梗粗榧
TCMBANKHE004405 Salvia candelabrum 烛台鼠尾草
TCMBANKHE004432 Clerodendron cyrtophyllum 路边青 To clear heat and resolve toxin, cool blood and stanch bleeding./Febrile diseases due to external contraction, exuberant heat and vexation thirst, swelling pain in throat, mouth sore, jaundice, heat toxin dysentery, acute enteritis, swelling toxin of welling abscess and flat abscess, spontaneous external bleeding, blood strangury, bleeding due to external injury.
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE006566 Cortex Moutan 牡丹皮 To remove heat from blood, to activate blood circulation and eliminate blood stasis./Appendicitis, dysentery, hypertension, allergic rhinitis, warm heat disease with fever, macular eruption, blood ejection, spontaneous external bleeding, steaming bone tidal fever due to yin vacuity, amenorrhea due to blood stasis, dysmenorrhea, concretion and conglomeration, swelling toxin of welling abscess and sore, painful wound from knocks and falls, wind-damp-heat impediment.
TCMBANKHE008921 Salvia miltiorrhiza f. alba 白花丹参 See Salvia miltiorrhiza ./See Salvia miltiorrhiza.
TCMBANKHE006799 Juniperus rigida 杜松实 To dispel wind, settle pain, eliminate damp, disinhibit urine./Rheumatic arthritis, pain wind, nephritis, edema, urinary tract infection.
TCMBANKHE007155 Radix Scrophulariae 玄参; 元参 To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity. Treatment of febrile diseases with impairment of yin manifested by deep red tongue and dire thirst, or with eruptions, constipation due to impairment of body fluid, phthisis with cough, conjunctivitis, sore throat, scrofula, diphtheria, boils and sores./Heat entering construction-blood, generalized fever, vexation and thirst, crimson tongue, macular eruption, steaming bone taxation cough, vacuity vexation and insomnia, fluid damage and constipation, dry eyes with clouded flowery vision, swelling pain in throat, scrofula with phlegm node, sore toxin of welling abscess and flat abscess. 1. Its alcoholic extract and its component methoxycinnamic acid can lower the typhoid vaccine-induced fever in rabbits.2. Its water or alcoholic infusion and decoction exert a mild hypotensive effect on anesthetized animals3. Lowering the level of blood sugar.4. Its infusion inhibits the growth of some dermatomyces.
TCMBANKHE008312 Juniperus communis 欧洲刺柏
TCMBANKHE005432/YNS-47/YEM-51/XU-527 Salvia przewalskii|Salvia przewalskii Maxim.var.mandarinorum(Diels) Stib.|Salvia przewalskii Maxim. 甘西鼠尾草|褐毛甘西鼠尾|甘西鼠尾 大紫丹参|甘西鼠尾 云南药材标准:第七册|云南民族药物志:第一卷|西藏昌都市芒康县 活血化瘀,通经止痛,清心安神。用于胸痹心痛,心烦失眠,脘腹胁痛,痛经、经闭、产后恶露不尽,风湿痹痛,癥瘕,疮疡肿痛。|See Salvia miltiorrhiza ./See Salvia miltiorrhiza . 彝族/藏族
TCMBANKHE008754/YEM-818 Salvia trijuga|Salvia trijuga Diels 三叶鼠尾草 三叶鼠尾 云南民族药物志:第四卷 To quicken blood and regulate menstruation, dispel stasis and engender flesh, boost kidney and quiet spirit./Menstrual disorder, dysmenorrhea, menstrual block, flooding, kidney vacuity lumbago, impotence, insomnia, frequent dreaming, knocks and falls. 藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000869 DRD2 D2DR; D2R dopamine receptor D2
TCMBANKGE000965 CHRNA7 CHRNA7-2; NACHRA7 cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1