Compound Summary


  Compound Information

药名:

glycyrrhizin

分子式:

C42H62O16

Smiles:

CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C

成分:

HBIN028191;HBIN028177

OB_score:

9.056951;19.617335

CAS_id:

103000-77-7;1405-86-3

SymMap_id:

SMIT00219;SMIT06723

TCMID_id:

23172

TCMSP_id:

MOL004932;MOL004876

PubChem_id:

14982


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000312 Radix Glycyrrhizae Preparata 炙甘草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000541 甘草头
TCMBANKHE000702 Radix Glycyrrhizae Praeparata 炙草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE001300 制军炭
TCMBANKHE001384 Radix Glycyrrhizae uralensis 甘草稍
TCMBANKHE003349 甘草节
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE008102/YEM-642 Herba Sedi sarmentosi|Sedum sarmentosum Bunge 垂盆草 垂盆草 云南民族药物志:第四卷 To remove damp-heat, and to counteract toxicity./1. Its amino acid protect the liver of rats and mice from CCl4 damage.2. Inhibiting the growth of Staphyloccus aureus, (a0 and (B) streptococcus and Shigella flexneri in vitro. 苗族/水族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000095 CYP11B2 ALDOS; CPN2; CYP11B; CYP11BL; CYPXIB2; P-450C18; P450C18; P450aldo cytochrome P450 family 11 subfamily B member 2
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000313 JUN AP-1; AP1; c-Jun; cJUN; p39 Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000318 HMGB1 HMG-1; HMG1; HMG3; SBP-1 high mobility group box 1
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE001069 MPO - myeloperoxidase
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001178 STAT3 ADMIO; ADMIO1; APRF; HIES signal transducer and activator of transcription 3
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE005259 GPT2 ALT2; GPT 2; MRT49 glutamic--pyruvic transaminase 2
TCMBANKGE006405 CCL11 SCYA11 C-C motif chemokine ligand 11
TCMBANKGE006866 HSD11B2 AME; AME1; HSD11K; HSD2; SDR9C3 hydroxysteroid 11-beta dehydrogenase 2