Compound Summary


  Compound Information

药名:

ligustrazine

分子式:

C8H12N2

Smiles:

CC1=C(N=C(C(=N1)C)C)C

成分:

HBIN033204

OB_score:

20.006909

CAS_id:

1124-11-4

SymMap_id:

SMIT00144;SMIT02487;SMIT19593;SMIT18640;SMIT14668

TCMID_id:

32715;23142;23489;24520;3633

TCMSP_id:

MOL002202

PubChem_id:

14296

DrugBank_id:

DB01643


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE005929 Radix et Rhizoma Notopterygii 羌活 To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE000673 毛叶威灵仙
TCMBANKHE000698 Radix Asparagi 天冬 To replenish yin, promote fluid secretion and moisten the lung./1. Asparamide is an expectorant, antitussive and antiasthmatic.2. Inhibiting the cell growth of acute lymphocytic, acute monocytic and chronic granulocytic leukemias in vitro.
TCMBANKHE001675 景天三七
TCMBANKHE002552 零陵香
TCMBANKHE002975 Oleum Curcumae 莪术油 Treatment of mass in the abdomen, amenorrhea due to blood stasis, distension and pain due to stagnation of undigested food, carcinoma of cervix at early stage./Its volatile oil and its components curcumenol, curdione and B-elemene destroy directly the Ehrlich-Ascites tumor and leukemia615 in mice.
TCMBANKHE003063 Herba Plantaginis 车前草 To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003562 山蓼
TCMBANKHE003724 Rhizoma Curcumae longae 姜黄 To eliminate blood stasis, promote the flow of qi, stimulate menstrual discharge and relieve pain./Gallstones, jaundice, leukaemia in early stage and carcinoma of uterine cervix in early stage, chronic ulcer, chronic scab, blood stasis and qi stagnation, pain in chest and abdomen and rib-side, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, wind-heat impediment pain, knocks and falls, swollen welling abscess.
TCMBANKHE003726 Cortex Cinmomi 肉桂 To supplement body fire, reinforce yang, and lead the fire back to the kidney, to dispel cold and relieve pain, and to activate blood circulation and stimulate menstrual discharge./Impotence, uterus cold, cold pain in lumbus and knees, kidney vacuity asthma, yang vacuity dizziness, red eyes and sore pharynx, cold pain in heart and abdomen, vacuity cold vomiting and diarrhea, cold mounting, running piglet, amenorrhea, dysmenorrhea.
TCMBANKHE003741 Vinegar To stanch bleeding and dissipate stasis, resolve toxin and kill worms./Postpartum blood dizziness, concretion and conglomeration, jaundice, yellow sweating, blood ejection, spontaneous external bleeding, hematochezia, itching in genital region, swelling of welling abscess, welling abscess and flat abscess with swelling sore.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003882 Semen Aesculi 娑罗子 To regulate the flow of qi, normalize the stomach function and relieve pain./Distending pain in chest and rib-side, distending pain in breast, dysmenorrhea, pain in stomach duct, pain in chest and abdomen.
TCMBANKHE003982 Ephedra equisetina 木贼麻黄 See Ephedra sinica./See Ephedra sinica.
TCMBANKHE006054 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE006322 Herba Inulae 金沸草 To relieve cough and dyspnea, and eliminate retained phlegm./Wind-cold cough, phlegm congestion and qi counterflow, glomus fullness in chest and diaphragm, cough and asthma with abundant phlegm, painful swelling from clove sore.
TCMBANKHE004582 Semen Juglandis 核桃仁 To tonify the kidney, to warm the lung, and to relax the bowels./It contains about 50% of fatty oil, exerting antitussive effect.
TCMBANKHE004973 Herba Ephedrae 麻黄 To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.
TCMBANKHE008104 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE007844 Flos Campsis 凌霄花 To promote blood circulation and remove blood stasis, to remove heat from the blood and dispel wind./Treatment of amenorrhea with mass in the abdomen, swelling of breast after childbirth, rubella red in colour, itching, acne.
TCMBANKHE005882 Fructus Mume 乌梅 To arrest persistent cough, to relieve diarrhea by astringing the intestines, to promote the production of body fluid, and to relieve colic caused by ascaris./Enduring cough, chronic diarrhea and dysentery, hematuria, hematochezia, flooding and spotting, vacuity heat with vexation and thirst, roundworm reversal with abdominal pain, outcrop of sore and welling abscess.
TCMBANKHE005958 Radix Clematidis 威灵仙 To relieve rheumatic conditions, to remove obstruction of collaterals, and to alleviate pain./Common cold, tonsillitis, acute icterohepatitis, laryngitis, rheumatic arthritis, wind-damp impediment pain, numbness in limbs, hypertonicity of sinews and vessels, bone stuck in throat.
TCMBANKHE006013 Semen Sojae Praeparata 淡豆豉 To induce diaphoresis, to ease the mind, and to relieve fever./Treatment of chills, fever and headache in colds and influenza, vexation, oppressed feeling in the chest and insomnia.
TCMBANKHE006116 Herba Inulae 金沸草 To relieve cough and dyspnea, and eliminate retained phlegm./Wind-cold cough, phlegm congestion and qi counterflow, glomus fullness in chest and diaphragm, cough and asthma with abundant phlegm, painful swelling from clove sore.
TCMBANKHE007984 Cynomorium songaricum 锁阳 To supplement kidney and invigorate yang , boost essence and blood, moisten intestines and free stool./Kidney vacuity impotence, emission and premature ejaculation, limp wilting of lower limb, vacuity constipation.
TCMBANKHE008098 Radix Curcumae 郁金 1. To invigorate blood and stop pain; 2. To promote qi circulation and release stagnation; 3. To cool blood and clear heat in the heart; 4. To relieve jaundice and facilitate gall bladder function/See Curcuma longa.
TCMBANKHE007628 Semen Euryales 芡实 1. To strengthen the kidney to preserve essence, drprive dampness to relieve leucorrhagia. 2. To strengthen the spleen to relieve diarrhea./1. Treatment of kidney-deficiency manifested as nocturnal emission, frequent micturition, enuresis, whitish and turbid urine, or leucorrhagia. 2. Treatment of diarrhea. For diarrhea of spleen-deficiency type.
TCMBANKHE006735/YEM-1032 Radix Smilacis|Smilax scobinicaulis C.H.Wright 灵仙|知梗菝葜 铁丝灵仙 云南民族药物志:第五卷 Treatment of rheumatic or rheumatoid arthralgia with numbness of the limbs, muscle contracture and limitation of motion, fish bone stuck in the throat./1. Inhibiting the growth of Stanphylococcus aureus and Shigella dysenteriae.2. Protoanemonin antagonizes histamine-induced bronchospasm and ileospam of guinea-pigs in vitro. 傈僳族
TCMBANKHE000065/YEM-1032 Smilax scobinicaulis C.H.Wright 金刚刺|知梗菝葜 铁丝灵仙 云南民族药物志:第五卷 傈僳族
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE005461/YEM-426 Rhizoma Curculiginis|Curculigo orchioides Gaertn. 仙茅 仙茅 云南民族药物志:第三卷 To reinforce the kidney yang, to strengthen the tendons and bones,and to dispel cold-damp./Impotence seminal cool, limp wilting sinew and bone, cold impediment in lumbus and knees, yang vacuity cold diarrhea. 阿昌族/白族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/苗族/佤族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000204 CXCL8 GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 C-X-C motif chemokine ligand 8
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE000452 CFTR ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-CFTR; dJ760C5.1 CF transmembrane conductance regulator
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE001148 VEGFA MVCD1; VEGF; VPF vascular endothelial growth factor A
TCMBANKGE009543 LTA LT; TNFB; TNFSF1; TNLG1E lymphotoxin alpha
TCMBANKGE009727 ITGA2B BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93 integrin subunit alpha 2b
TCMBANKGE010979 TBXAS1 BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS thromboxane A synthase 1
TCMBANKGE011547 APOC3 APOCIII apolipoprotein C3
TCMBANKGE013786 ASIC3 ACCN3; DRASIC; SLNAC1; TNaC1 acid sensing ion channel subunit 3
TCMBANKGE014262 CYP11B1 CPN1; CYP11B; FHI; P450C11 cytochrome P450 family 11 subfamily B member 1
TCMBANKGE014865 ATP2A2 ATP2B; DAR; DD; SERCA2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2