Compound Summary


  Compound Information
化合物待补充

药名:

vitamin b1

分子式:

C63H88CoN14O14P

Smiles:

CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)(O)OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+2]

成分:

HBIN048039;HBIN048043

SymMap_id:

SMIT01658;SMIT02671;SMIT02672;SMIT01808;SMIT02670

TCMID_id:

22538;23572

PubChem_id:

54605677

DrugBank_id:

DB00152;DB00140


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000207 Saccharum granorum 饴糖 For tonifying qi
TCMBANKHE000232 川射干
TCMBANKHE000845 semen zizphi spinosae 枣仁 Treatment of insomnia, dream-disturbed sleep, excessive sweating due to debility, thirst due to consumption of body fluid./The chief components are jujuboside A and B. 1. Intraperitoneal injection its decoction ( 2.5-5.0g/kg ) exerts sedative and hypnotic effects in rats. 2. Intravenous injection of its decoction exerts significant and proloned hypotensive effect in anesthetized dogs. 3. Occasionally causing heart block. 4. Inducing hysterospasm.
TCMBANKHE000955 Polysaccharidum Versicolor 云芝
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001282 瓦松
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE001875 Herba Clinopodii 断血流 To arrest bleeding./Treatment of excessive menstrual discharge, hemorrhage from hysteromyoma, hematuria, epistaxis, gingival bleeding, traumatic bleeding.
TCMBANKHE002002 Pedicellus Melo 甜瓜蒂 1. To remove lumps, eliminate fluid and relieve jaundice. For acute and chronic viral hepatitis, hepatocirrhosis and liver cancer. 2. Emetic. For accumulation of phlegm, epilepsy due to wind-phelgm, persistent dyspepsis, etc./1. To remove lumps, eliminate fluid and relieve jaundice. For acute and chronic viral hepatitis, hepatocirrhosis and liver cancer. 2. Emetic. For accumulation of phlegm, epilepsy due to wind-phelgm, persistent dyspepsis, etc.
TCMBANKHE002642 冬瓜子 Phlegm-heat cough, pulmonary welling abscess, intestinal welling abscess, white turbidity, vaginal discharge, beriberi, edema, strangury syndrome.
TCMBANKHE002715 Semen Phaseoli Radiati 绿豆 1. To clear heat and toxic materials, clear summer-heat and promote diuresis. 2. To relieve the metallic and drug poisoning. 3. External use for clearing away heat and promoting tissue regeneration. 4. To reduce the level of blood-fat./1. Diuretic. 2. Its coat exerts a bacteriostatic effect on staphylococcus.
TCMBANKHE003063 Herba Plantaginis 车前草 To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003123 radix vitis romanetii 野葡萄根
TCMBANKHE003732 Ganoderma Lucidum seu Japonicum 灵芝(赤芝) Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis.
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE003826 Rhizoma Cimicifugae 升麻 To induce perspiration and promote eruption, to remove toxic heat, and to cure drooping and ptosis./Prevention of ptosis, women’s hormone dysfunction diseases, seasonal epidemic fire toxin, mouth sore, sore pharynx, macula, cold-heat headache, swelling toxin of welling abscess and sore, center qi fall, spleen vacuity diarrhea, chronic dysentery, vaginal discharge, flooding.
TCMBANKHE003863 Herba Cichorii 菊苣 To remove heat from the liver, to stimulate the discharge of bile, to promote digestion and increase appetite, and to cause diuresis./Treatment of jaundice caused by damp-heat, epigastric pain with impairment of appetite, edema with oliguria.
TCMBANKHE004022 Cordyceps 冬虫夏草 To tonify the lung and the kidney, arrest bleeding, and dispel phlegm./Impotence and emission, neurasthenia, backache, aching in lumbus and knees, enduring cough and vacuity asthma, taxation damage hemoptysis.
TCMBANKHE007954 Flos Rhododendri Mollis 闹羊花 To relieve rheumatic conditions, and to eliminate blood stasis and alleviate pain./Tachycardia, palpitation, hypertension, wind-damp impediment pain, knocks and falls, intractable lichen.
TCMBANKHE004258 Radix Angelicae sinensis 当归根 To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE004260 Radix Ginseng 人参 To reinforce the vital energy, to remedy collapse and restore the normal pulse, to benefit the spleen and lung, to promote the production of body fluid, and to calm the nerves./Qi vacuity and verging on desertion, cold limbs and faint pulse, reduced food intake due to spleen vacuity, cough and asthma due to lung vacuity, fluid damage and thirst, diabetes mellitus due to internal heat, enduring illness qi vacuity, fright palpitation and insomnia, impotence, uterus cold, cardiac failure.
TCMBANKHE006054 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE006212 Semen Astragali Complanati;Semen Astragali Complati 潼蒺藜;沙苑子 Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
TCMBANKHE007730 Fructus Meliae Toosendan 川楝子 To relieve pain by smoothing the flow of the liver qi and to repel worms./Chest and rib-side pain, distending pain in stomach duct, mounting qi , abdominal pain due to worm accumulation.
TCMBANKHE006403 Herba Schizonepetae 荆芥 To induce diaphoresis, to dispel wind, and to promote eruptions./Common cold with fever, headache, itchy eye, cough, swelling pain in throat, measles papules, wind papules, swollen welling abscess, sore and scab, throat pain, conjunctivitis, child measles, spontaneous external bleeding, blood ejection, hematochezia, flooding and spotting, postpartum blood dizziness.
TCMBANKHE004636 Fructus Zizyphi Jujubae 大枣 To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE004843 Cervus nippon , Cervus elaphus 鹿茸 To supplement kidney and invigorate yang , boost essence and blood, strengthen sinews and bones, regulate thoroughfare and controlling vessels, draw sore toxin./Impotence and emission, infertility due to uterus cold, marked emaciation, thrombocytopenia, septicemia, fatigued spirit, aversion of cold, dizziness, tinnitus and deafness, aching pain in lumbus and back, limp wilting sinew and bone, flooding and spotting with vaginal discharge, enduring yin flat abscess.
TCMBANKHE004973 Herba Ephedrae 麻黄 To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.
TCMBANKHE005328 Radix Stellariae 银柴胡 1. To reduce heat caused by deficient yin; 2. To clear heat in infants caused by malnutrition/Yin vacuity fever, steaming bone taxation fever, child gan fever.
TCMBANKHE008104 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE005544 Celosia cristada 鸡冠子
TCMBANKHE005555 绞股蓝 Vacuity and hypodynamia, septicemia, hyperlipemia, viral hepatitis, chronic gastroenteritis, chronic trachitis.
TCMBANKHE007628 Semen Euryales 芡实 1. To strengthen the kidney to preserve essence, drprive dampness to relieve leucorrhagia. 2. To strengthen the spleen to relieve diarrhea./1. Treatment of kidney-deficiency manifested as nocturnal emission, frequent micturition, enuresis, whitish and turbid urine, or leucorrhagia. 2. Treatment of diarrhea. For diarrhea of spleen-deficiency type.
TCMBANKHE006133 紫苏 Phlegm congestion and qi counterflow, cough and asthma, intestinal dry and constipation.
TCMBANKHE008343 Radix Trichosanthis 天花粉 To remove heat, to promote the production of body fluid, and to facilitate the drainage of pus and the subsidence of swelling./Febrile diseases thirst, lung heat dry cough, diabetes mellitus due to internal heat, toxin swelling of sores, induce abortion.
TCMBANKHE009190 Fructus Mori 桑椹 To nourish n and blood and promote the production of body fluid./Its contains sugar, organic acid , vitamins B1, B2 and C and carotene. Its oleum contains oleic acid and linoleic acid.
TCMBANKHE006504 Gallus gallus domesticus 鸡内金 To fortify spleen and disperse food, rough essence and arrest emission, disperse concretion and transform stone./Indigestion, food stagnation, vomiting nausea, diarrhea and dysentery, child gan accumulation, emission, enuresis, frequent urination, calculus of urinary system, gallstones, amenorrhea with concretion and conglomeration, throat impediment with nipple moth, gan of teeth and gum, mouth sore.
TCMBANKHE008341 Fructus Zizyphi Jujubae 大枣 To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE006949 Hippophae rhamnoides 醋柳果 To relieve cough and transform phlegm, fortify stomach and disperse food, quicken blood and dissipate stasis./Cough with profuse phlegm, pulmonary welling abscess, indigestion, food accumulati on abdominal pain, stomachache, enteritis, amenorrhea, stasis swelling from knocks and falls.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE008798 Malus pumila 苹果 To boost stomach, engender liquid, eliminate vexation, arouse liquor./Scant fluid and thirst, spleen vacuity diarrhea, food retention and abdominal distention, resolve liquor toxin.
TCMBANKHE008690 Pericarpium Citri Reticulatae 陈皮 To regulate the flow of qi, to invigorate the spleen function, to eliminate damp, and to resolve phlegm./Treatment of distension and fullness sensation in the chest and epigastrium with anorexia, vomiting and diarrhea, cough with copious phlegm.
TCMBANKHE009030 Resi myrrhae;Myrrha 没药 1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall.
TCMBANKHE008880 Vitex rotundifolia [Syn. Vitex trifollia var. simplicifolia ] 单叶蔓荆子 See Vitex trifolia./See Vitex trifolia .
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE004034/YEM-290/YEM-296 Oryza sativa|Oryza sativa L.var. glutinosa Matsum. 米皮糠|糯稻 糯稻 云南民族药物志:第二卷 To increase appetite, precipitate qi./Dysphagia-occlusion, beriberi . 白族/傣族/哈尼族/彝族
TCMBANKHE004010/YEM-314 fructus vitis viniferae|Vitis vinifera L. 葡萄 葡萄 云南民族药物志:第二卷 傣族/藏族
TCMBANKHE006191/YEM-346 Arillus Longan|Dimocarpus longan Lour. 龙眼肉|龙眼 龙眼 云南民族药物志:第二卷 Treatment of cardiac palpitation, forgetfulness and insomnia due to deficiency of qi and blood, anemia./Treatment of cardiac palpitation, forgetfulness and insomnia due to deficiency of qi and blood, anemia. 傈僳族/瑶族/壮族
TCMBANKHE005494/YEM-445 Fructus Hordei Germitus|Hordeum vulgare L. 麦芽|大麦 大麦 云南民族药物志:第三卷 To invigo rate the function of the spleen, to regulate the function of the stomach, and to promote the flow of milk./Food accumulation, abdominal distention and diarrhea, nausea and vomiting, inappetence, galactostasis, distending pain in breast. 佤族/彝族
TCMBANKHE006470/YEM-531 Siphonostegia chinensis|Siphonostegia chinensis Benth. 阴行草 阴行草 云南民族药物志:第三卷 To clear heat and disinhibit damp, quicken blood and dispel stasis./Jaundice, inhibited urination, abdominal distention with edema, stasis pain from knocks and falls, blood dysentery, blood strangury, vaginal discharge, menstrual disorder, concretion conglomeration accumulation and gathering, postpartum abdomin al pain. 布依族/傈僳族/苗族/纳西族/壮族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE006261/YEM-689 Rhizoma Phragmitis|Phragmites communis Trin. 芦根|芦苇 芦苇 云南民族药物志:第四卷 To remove heat, to promote the production of body fluid, to relieve emesis, and to alleviate dysuria./Febrile diseases with vexation and thirst, stomach heat vomiting, lung heat cough, pulmonary welling abscess, heat strangury with inhibited pain. 阿昌族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/水族/佤族/彝族/壮族
TCMBANKHE006962/YEM-697/XU-461 Taraxacum mongolicum|Taraxacum mongolicum H.-M. 蒲公英 蒲公英 云南民族药物志:第四卷|云南省昆明市呈贡区梁王山 To clear heat and resolve toxin, dissipate binds and disperse swelling, disinhibit urine and free strangury./Epidemic parotitis, infection of upper respiratory tract, tonsillitis, laryngitis, sore pharynx, mastitis, hepatitis, swelling toxin of clove sore, mammary welling abscess, scrofula, red eyes, pulmonary welling abscess, damp-heat jaundice, heat strangury with inhibited pain. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE007941/YEM-822 Herba Schizonepetae|Schizonepeta tenuifolia(Benth.)Briq. 荆芥|裂叶荆芥 裂叶荆芥 云南民族药物志:第四卷 To induce diaphoresis, to dispel wind, and to promote eruptions./Common cold with fever, headache, itchy eye, cough, swelling pain in throat, measles papules, wind papules, swollen welling abscess, sore and scab, throat pain, conjunctivitis, child measles, spontaneous external bleeding, blood ejection, hematochezia, flooding and spotting, postpartum blood dizziness. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE007939/YEM-89 Rhizoma Fagopyri Cymosi|Fagopyrum dibotrys (D.Don)Hara 金荞麦 金荞麦 云南民族药物志:第一卷 1. Its extractum and component flavanol promotes macrophage phagocytosis in the peritoneum of mouse.2. Flavanol is also an anti-inflammatory component. It promotes blood circulation and inhibits the agglutination of blood platelet./1. To clear heat and toxic material. For lung abscess, cough due to lung-heat, also for sorethroat and skin infection. 2. To promote blood circulation to eliminate blood stasis. For menorrhalgia due to blood stasis, postpartum abdominal pain due to blood 傣族/哈尼族/基诺族/彝族/藏族
TCMBANKHE003869/YEM-999/XU-341 Folium Isatidis|Isatis indigotica Fort.|Isatis indigotica 板蓝根(大青叶)|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To clear heat and toxic materials, cool blood and eliminate eruption./Acute parotitis, encephalitis, hepatitis, lung abscess, acute gastroenteritis, infection of upper respiratory tract, warm evil in construction, ardent fever with clouded spirit, macular eruption and papules, jaundice, heat dysentery, epidemic parotitis, throat impediment, erysipelas, swollen welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000048 Neoplasms group Neoplasms 28911109
TCMBANKDI015740 Colorectal Neoplasms group Digestive System Diseases; Neoplasms 21693628
TCMBANKDI019359 Adenoma group Neoplasms 21693628
TCMBANKDI020079 Multiple Acyl Coenzyme A Dehydrogenase Deficiency disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases 30232818
TCMBANKDI024649 Neuroblastoma disease Neoplasms 24884571
TCMBANKDI031985 Brain Ischemia disease Nervous System Diseases; Cardiovascular Diseases 30014516

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000209 IZUMO1R FOLR4; FR-delta; Folbp3; JUNO IZUMO1 receptor, JUNO
TCMBANKGE000340 ACP5 HPAP; TRACP5a; TRACP5b; TRAP; TrATPase acid phosphatase 5, tartrate resistant
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001149 PPARGC1A LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 PPARG coactivator 1 alpha
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53
TCMBANKGE001540 FOLR1 FBP; FOLR; FRalpha folate receptor alpha
TCMBANKGE001990 ACP4 ACPT; AI1J acid phosphatase 4
TCMBANKGE003333 PYGL GSD6 glycogen phosphorylase L
TCMBANKGE005688 ACP1 HAAP; LMW-PTP; LMWPTP acid phosphatase 1
TCMBANKGE007644 FOLR2 BETA-HFR; FBP; FBP/PL-1; FOLR1; FR-BETA; FR-P3; FRbeta folate receptor beta
TCMBANKGE008501 ACP3 5'-NT; ACP-3; ACPP; TM-PAP acid phosphatase 3
TCMBANKGE008896 BLVRB BVRB; FLR; HEL-S-10; SDR43U1 biliverdin reductase B
TCMBANKGE013144 SLC52A3 BVVLS; BVVLS1; C20orf54; RFT2; RFVT3; bA371L19.1; hRFT2 solute carrier family 52 member 3
TCMBANKGE015109 RFK RIFK riboflavin kinase