Compound Summary

  Compound Information

TCMBANKIN060018

药名:	Costunolide
分子式:	C15H20O2
Smiles:	CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C
成分:	HBIN021599; HBIN021600
OB_score:	29.070333; 60.482537
CAS_id:	553-21-9
SymMap_id:	SMIT11810;SMIT14772;SMIT00796
TCMID_id:	4128;30816
TCMSP_id:	MOL010825;MOL010826
PubChem_id:	133640194

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002834	Radix Aucklandiae	广木香			Regulation of qi
TCMBANKHE004907		连钱草			Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE007831	Vladimiria denticulata	越西木香			To rectify qi , relieve pain./Pain in stomach duct and rib-side, diarrhea, dysentery, indigestion.
TCMBANKHE005842	Vladimiria souliei [Syn. Jurinea souliei]	川木香			To move qi and relieve pain./Distending pain in stomach duct, rumbling intestines and diarrhea, tenesmus, liver gallbladder pain.
TCMBANKHE007295	Radix Aucklandiae	木香			To relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. /Distending pain in chest and stomach duct, diarrhea and tenesmus, non-digestion of food accumu lation, no thought of food and drink.
TCMBANKHE008945	Laurus nobilis	月桂子			To dispel wind-damp, resolve toxin, kill worms./Wind-damp impediment pain, tetrodon poisoning, scab and lichen, postauricular sore.
TCMBANKHE004275/YEM-156	Inula helenium|Inula helenium L.	土木香	土木香	云南民族药物志：第一卷	To fortify spleen and harmonize stomach, regulate qi and resolve depression, relieve pain and quiet fetus./Distending pain in chest and rib-side, distending pain in stomach duct, vomiting and diarrhea, contusion in chest and rib-side, forking qi with pain, stirring fetus in pregnancy.	阿昌族/傣族/哈尼族/景颇族/傈僳族/藏族
TCMBANKHE006668/YEM-19	Aquilaria sinensis|Aquilaria sinensis (Lour.) Spreng.	白木香	沉香	云南民族药物志：第一卷	See Aquilaria agallocha./See Aquilaria agallocha .	阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005473/YEM-262	Momordica cochinchinensis|Momordica cochinchinensis(Lour.)Spreng	木鳖根|木鳖子	木鳖子	云南民族药物志：第二卷	To resolve toxin, disperse distention, relieve pain./Welling abscess and toxin of clove, innominate toxin swelling, lymphrnoditis.	傣族/哈尼族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000008	Brain Neoplasms	group	Neoplasms; Nervous System Diseases	27148686
TCMBANKDI000022	Prostatic Neoplasms	group	Neoplasms; Male Urogenital Diseases	21421237
TCMBANKDI000086	Colonic Neoplasms	group	Digestive System Diseases; Neoplasms	29037867
TCMBANKDI004589	Breast Carcinoma	disease	Neoplasms; Skin and Connective Tissue Diseases	24028602
TCMBANKDI008155	Micronuclei, Chromosome-Defective	phenotype	Pathological Conditions, Signs and Symptoms	28914393
TCMBANKDI026275	Glioblastoma	disease	Neoplasms	27148686

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000221	GRIA2	GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B	glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000313	JUN	AP-1; AP1; c-Jun; cJUN; p39	Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000940	TERT	CMM9; DKCA2; DKCB4; EST2; PFBMFT1; TCS1; TP2; TRT; hEST2; hTRT	telomerase reverse transcriptase
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE002334	TEP1	TLP1; TP1; TROVE1; VAULT2; p240	telomerase associated protein 1
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1