Compound Summary


  Compound Information

药名:

harmine

分子式:

C13H12N2O

Smiles:

CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC

成分:

HBIN028803; HBIN048577

OB_score:

56.800218

CAS_id:

442-51-3

SymMap_id:

SMIT01439; SMIT09838

TCMID_id:

9234

TCMSP_id:

MOL008570

PubChem_id:

5280953

DrugBank_id:

DB07919


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000889 Fructus Tribuli 白蒺藜 Treatment of headache and dizziness, distending pain in the chest and costal regions, cessation of milk secretion, mastitis, redness of the eye with formation of nebula, urticaria with itching./Treatment of headache and dizziness, distending pain in the chest and costal regions, cessation of milk secretion, mastitis, redness of the eye with formation of nebula, urticaria with itching.
TCMBANKHE008218 Trema dielsiana 山油麻 To relieve pain, stanch bleeding./Boil.
TCMBANKHE004414 Elaeagnus angustifolia 沙枣 To nourish liver and boost kidney, fortify spleen and regulate menstruation./Liver vacuity dim vision, kidney vacuity lumbago, spleen vacuity diarrhea, indigestion, vaginal discharge, menstrual disorder.
TCMBANKHE004610 Ramulus Uncariae cum Uncis 钩藤 To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache.
TCMBANKHE005119 Passiflora incarnata 粉红色西番莲
TCMBANKHE008416 Symplocos racemosa 煮紫薯;珠仔树
TCMBANKHE006129 Thalictrum foetidum 香唐松草 To clear heat and dry damp, resolve toxin./Damp-heat dysentery, jaundice, red eyes with gall, swollen welling abscess, sore and boil, wind-damp-heat impediment.
TCMBANKHE008649 Ophiorrhiza japonica 日本蛇根草 To relieve cough and dispel phlegm, quicken blood and regulate menstruation./Cough, taxation damage and blood ejection, hematochezia, dysmenorrhea, menstrual disorder, pain in sinews and bones, sprain and contusion.
TCMBANKHE008744 Tribulus terrestris 刺蒺藜 To dissipate wind and brighten eyes, precipitate qi and move blood./Headache, itchy body, red eyes and eye screen, convulsion, fullness in chest, cough and counterflow, concretion and conglomeration, difficult lactation, welling abscess and flat abscess, scrofula.
TCMBANKHE005763/XU-552 Peganum harmala 骆驼蓬子|骆驼蓬 甘肃省定西市岷县 To relieve cough and calm asthma, dispel wind-damp, resolve depression./Cough and asthma, inhibited urination, numbness in limbs, aching pain in joints.
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE006990 Passiflora edulis 鸡蛋果 To clear lung and moisten dryness, quiet spirit and relieve pain, harmonize blood and check dysentery./Cough, dry throat, hoarseness, constipation, insomnia, dysmenorrhea, pain in joints, dysentery.
TCMBANKHE006949 Hippophae rhamnoides 醋柳果 To relieve cough and transform phlegm, fortify stomach and disperse food, quicken blood and dissipate stasis./Cough with profuse phlegm, pulmonary welling abscess, indigestion, food accumulati on abdominal pain, stomachache, enteritis, amenorrhea, stasis swelling from knocks and falls.
TCMBANKHE005696/XU-552 Peganum harmala 骆驼蓬 甘肃省定西市岷县 To diffuse lung qi, dispel wind-damp, disperse swelling toxin./Cough and shortness of breath, wind-damp impediment pain, itchy skin, innominate toxin swelling.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE007889 杜仲叶 Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE003831/YEM-100 Polygala tenuifolia|Polygala sibirica L. 远志|西伯利亚远志 苦远志 云南民族药物志:第一卷 To quiet heart and spirit, dispel phlegm and open orifices, resolve toxin and disperse swelling./Pharyngitis, disquieted heart spirit, fright palpitation and insomnia, amnesia, fright epilepsy, cough with profuse phlegm, effusion of back from welling abscess and flat abscess, painful swollen breast. 白族/拉祜族/傈僳族/纳西族/佤族/瑶族/壮族
TCMBANKHE005257/YEM-104 Folium Nelumbinis|Nelumbo nucifera Gaertn. 荷叶|莲 云南民族药物志:第一卷 To relieve summer-heat, to invigorate the spleen function of the spleen and arrest bleeding by reducing heat in blood./Summerheat-heat vexation and thirst, summerheat-damp diarrhea, spleen vacuity diarrhea, blood heat, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000075 Diabetes disease Endocrine System Diseases 25751815

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000406 CDKL5 CFAP247; EIEE2; ISSX; STK9 cyclin dependent kinase like 5
TCMBANKGE000407 DYRK1A DYRK; DYRK1; HP86; MNB; MNBH; MRD7 dual specificity tyrosine phosphorylation regulated kinase 1A
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1