Compound Summary


  Compound Information

药名:

isocorynoline

分子式:

C20H23NO4

Smiles:

CC12C(CC3=CC4=C(C=C3C1N(CC5=C2C=CC6=C5OCO6)C)OCO4)O

成分:

HBIN030611; HBIN025323; HBIN001452; HBIN002081; HBIN021572

OB_score:

47.439489; 3.995306; 46.059583; 30.531631

CAS_id:

475-67-2; 51151-82-7; 18797-79-0

SymMap_id:

SMIT00735; SMIT09890; SMIT06160; SMIT00734

TCMID_id:

11343; 4116; 6873

TCMSP_id:

MOL008640; MOL008639; MOL004198; MOL008636

PubChem_id:

56842002; 177014


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001007 Corydalis tuberosa
TCMBANKHE003276 Artabotrys suaveolens
TCMBANKHE004003 Rauwolfia serpentina 印度萝芙木 To lower blood pressure./Hypertension.
TCMBANKHE004103 Mahonia aquifolium 尖叶十大功劳
TCMBANKHE004376 Pericarpium Grati 石榴皮 To check diarrhea, arrest bleeding and repel worms./Chronic diarrhea, chronic dysentery, hematochezia, prolapse of rectum, flooding and spotting, leukorrhea, abdominal pain due to worm accumulation.
TCMBANKHE006167 Herba Corydalis bungeae 苦地丁 Influenza, infection of upper respiratory tract, tonsillitis, infective hepatitis, enteritis, dysentery, nephritis, parotitis, conjunctivitis, acute appendicitis, clove sore and swollen welling abscess, scrofula.
TCMBANKHE004522 Rhizoma Corydalis 延胡索 1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls.
TCMBANKHE005184 Peucedanum rubricaule 云前胡 See Angelica decursiva./See Angelica decursiva .
TCMBANKHE005216 Corydalis cava 凹陷紫堇
TCMBANKHE007317 Holarrhena antidysenterica 止泻木皮 To move qi and check diarrhea, kill worms./Dysentery, gastrointestinal flatulence.
TCMBANKHE006524 Nandina domestica 南天竹子 To constrain lung and relieve cough, calm asthma./Enduring cough, asthma, pertussis.
TCMBANKHE008498 fructus Sophorae 槐角 For cooling blood and stopping bleeding
TCMBANKHE007194 Thalictrum urbainii 台湾唐松草
TCMBANKHE008052 Corydalis incisa 紫花鱼灯草 To resolve toxin and kill worms, relieve pain./Toxin swelling of sores, scab and lai, intractable lichen, eczema, poisonous snake bite.
TCMBANKHE006958 Papaver commutatum [Syn. Papaver rhoeas ] 丽春花 To suppress cough, settle pain, check diarrhea./Cough, migraine, abdominal pain, dysentery.
TCMBANKHE007291 Corydalis suaveolens [Syn. Corydalis sheareri] 尖距紫堇 To quicken blood and relieve pain, clear heat and resolve toxin./Stomachache, abdominal pain and diarrhea, knocks and falls, swelling toxin of welling abscess and sore, red eyes with gall.
TCMBANKHE004351/YEM-1003 Litsea cubeba|Litsea cubeba(Lour.)Pers. 澄茄子|山鸡椒 木姜子 云南民族药物志:第五卷 To warm center and relieve pain, move qi and quicken blood, calm asthma, disinhibit urine./Chronic bronchitis, bronchial asthma, asthma, cold pain in stomach duct and abdomen, food accumulation and qi distention, stomach reflux vomiting, summerheat stroke with vomiting and diarrhea, diarrhea, cold mounting with abdominal pain, cold-damp water drum distention, inhibited urination, opacity of urine, toxin swelling of sores, toothache, cold-damp impediment pain, knocks and falls. 傣族/德昂族/景颇族/傈僳族/水族/佤族/彝族/壮族
TCMBANKHE000400/YEM-1035 Stephania brachyandra|Stephania brachyandra Diels 白鲜树|白线薯 一滴血 云南民族药物志:第五卷 To move qi and quicken blood, dispel wind and relieve pain, clear heat and resolve toxin./Stomachache, wind-damp impediment pain, knocks and falls, dysmenorrhea, swelling toxin of welling abscess and boil, eczema. 傣族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1