Compound Summary


  Compound Information

药名:

14-deoxy-11-oxoandrographolide

分子式:

C20H28O5

Smiles:

CC12CCC(C(C1CCC(=C)C2C(=O)CC3=CC(=O)OC3)(C)CO)O

成分:

HBIN001408

OB_score:

57.055826

SymMap_id:

SMIT00350

TCMID_id:

5199

TCMSP_id:

MOL008203

PubChem_id:

101593061


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001532 日本萍逢草
TCMBANKHE003976 Periostracum Cicadae 蝉蜕 To dispel wind-heat, to soothe sore throat, to promote eruption, to clear the eye of corneal opacity, and to arrest spasm.;Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus./Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE009019 Nuphar luteum 欧洲萍逢草
TCMBANKHE004755 Semen Impatientis 急性子 To remove stagnation of qi, eliminate blood stasis, and soften hard masses./Concretion and conglomeration, lump glomus, amenorrhea, dysphagia-occlusion.
TCMBANKHE007748/YEM-22/XU-390 Herba andrographitis|Andrographis paniculata (Burm. f,)Nees|Andrographis paniculata 穿心莲 穿心莲 云南民族药物志:第一卷|云南省普洱市镇沅县 1. To clear heat and release toxins; 2. To dry dampness/Infection of upper respiratory tract, fever, wind-heat common cold, bacillary dysentery, diarrhea, tonsillitis, pneumonia, tuberculosis, lung heat cough, pulmonary welling abscess, postlithotripsy urinary tract infection, warm disease fever, pertussis, swelling pain in throat, damp-heat jaundice, strangury syndrome, erysipelas, sore and welling abscess, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE006576/YEM-61/XU-569 Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella 诃子|微毛诃子 诃子 云南民族药物志:第一卷|云南省临沧市永德县 To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE002388 NR3C2 MCR; MLR; MR; NR3C2VIT nuclear receptor subfamily 3 group C member 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2