Compound Summary


  Compound Information

药名:

isoandrographolide;12-dideoxyhydro-andrographolide;andrographolide

分子式:

C20H30O5

Smiles:

CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O

成分:

HBIN030423;HBIN016019;HBIN000784

SymMap_id:

SMIT02388;SMIT01269

TCMID_id:

29746;25035;1159


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003250 Folium Andrographitis 穿心莲叶
TCMBANKHE003976 Periostracum Cicadae 蝉蜕 To dispel wind-heat, to soothe sore throat, to promote eruption, to clear the eye of corneal opacity, and to arrest spasm.;Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus./Treatment of upper respiratory infection with sore throat, hoarseness of voice, measles with inadequate eruption, urticaria with itching, inflammation of the eye with formation of corneal opacity, convulsion, tetanus.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE006133 紫苏 Phlegm congestion and qi counterflow, cough and asthma, intestinal dry and constipation.
TCMBANKHE007747 Andrographis elongata 穿心莲
TCMBANKHE007748/YEM-22/XU-390 Herba andrographitis|Andrographis paniculata (Burm. f,)Nees|Andrographis paniculata 穿心莲 穿心莲 云南民族药物志:第一卷|云南省普洱市镇沅县 1. To clear heat and release toxins; 2. To dry dampness/Infection of upper respiratory tract, fever, wind-heat common cold, bacillary dysentery, diarrhea, tonsillitis, pneumonia, tuberculosis, lung heat cough, pulmonary welling abscess, postlithotripsy urinary tract infection, warm disease fever, pertussis, swelling pain in throat, damp-heat jaundice, strangury syndrome, erysipelas, sore and welling abscess, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000868 NFATC1 NF-ATC; NF-ATc1.2; NFAT2; NFATc nuclear factor of activated T cells 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001079 CYP1A1 AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX cytochrome P450 family 1 subfamily A member 1
TCMBANKGE001161 IL2 IL-2; TCGF; lymphokine interleukin 2
TCMBANKGE001162 IFNG IFG; IFI interferon gamma
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE007368 GSTP1 DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI glutathione S-transferase pi 1
TCMBANKGE012574 MAPK12 ERK-6; ERK3; ERK6; MAPK 12; P38GAMMA; PRKM12; SAPK-3; SAPK3 mitogen-activated protein kinase 12
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A