Compound Summary


  Compound Information

药名:

gamabufotalin

分子式:

C24H34O5

Smiles:

CC12CCC(CC1CCC3C2C(CC4(C3(CCC4C5=COC(=O)C=C5)O)C)O)O

成分:

HBIN027073; HBIN027072; HBIN037518

OB_score:

36.320348

CAS_id:

465-11-2

SymMap_id:

SMIT15449; SMIT10324

TCMID_id:

24393; 8120

TCMSP_id:

MOL009157

PubChem_id:

259803


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE005508 Bufo bufo gargarizans, Bufo melanostictus 蟾酥 To resolve toxin, relieve pain, open orifices and arouse spirit./Welling abscess and flat abscess with clove sores, swelling pain in throat, summerheat stroke with vomiting and diarrhea, abdominal pain and clouded spirit, local anesthesia.
TCMBANKHE004086 Plumula Nelumbinis 莲子心 To remove heat from the heart and calm the nerves, to restore the coordination between the heart and the kidney, to check emission, and to arrest bleeding./Heat entering pericardium, clouded spirit with delirious speech, non-interaction of heart and kidney, insomnia and emission, blood ejection due to blood heat, hypertension.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE004534/XU-848 Equisetum arvense 问荆 云南省红河州屏边县 To stanch bleeding, disinhibit urine, brighten eyes./Spontaneous external bleeding, blood ejection, hemoptysis, hematochezia, flooding and spotting, bleeding due to external injury, red eyes and eye screen.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI026275 Glioblastoma disease Neoplasms 31746080

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000663 AQP4 MIWC; WCH4 aquaporin 4
TCMBANKGE000664 ATP1A3 AHC2; ATP1A1; CAPOS; DYT12; RDP ATPase Na+/K+ transporting subunit alpha 3
TCMBANKGE002388 NR3C2 MCR; MLR; MR; NR3C2VIT nuclear receptor subfamily 3 group C member 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor