Compound Summary

  Compound Information

TCMBANKIN060247

药名:	Saikosaponin D
分子式:	C42H68O13
Smiles:	CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC56C4(CC(C7(C5CC(CC7)(C)C)CO6)O)C)C)C)O)OC8C(C(C(C(O8)CO)O)O)O)O
成分:	HBIN042801;HBIN042802
OB_score:	34.393887
CAS_id:	20874-52-6
SymMap_id:	SMIT06523;SMIT17533
TCMID_id:	19133;23079
TCMSP_id:	MOL004637
PubChem_id:	137705034

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004980	Bupleurum scorzonerifolium	红柴胡			See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE004172	Radix Bupleuri	柴胡			To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE004524	Herba Polygoni Avicularis	萹蓄			To relieve dysuria, to kill parasites and to alleviate itching./Urethritis, lithiasis, chyluria, dysentery, parotitis, heat strangury, short voidings of reddish urine, dripping with inhibited pain, eczema, pudendal itch, vaginal discharge, ascariasis.
TCMBANKHE004641	Bupleurum falcatum	紫胡
TCMBANKHE005148	Bupleurum longiradiatum	大叶柴胡			See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE006024	Bupleurum smithii var. parvifolium	小叶黑柴胡			See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE006304	Bupleurum yinchowense	银州柴胡			See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE007288	Bupleurum smithii	黑柴胡
TCMBANKHE007334	Bupleurum angustissimum	线叶柴胡			See Bupleurum chinense ./See Bupleurum chinense .
TCMBANKHE003973/YNS-60/YEM-200	Bupleurum marginatum|Bupleurum marginatum Wall.ex DC. 和 B.hamiltonii N.P.Balak|Bupleurum marginatum Wall.	竹叶柴胡|竹叶柴胡和小柴胡	滇柴胡|竹叶柴胡	云南药材标准：第七册|云南民族药物志：第一卷	和解少阳，平肝解郁，调经。用于少阳病寒热往来，口苦咽干，胸胁胀满，头痛目眩，月经不调，中气下陷。|See Bupleurum chinense./See Bupleurum chinense.	彝族/藏族
TCMBANKHE004008/YEM-522	Sansevieria trifasciata|Sansevieria trifasciata Prain	虎尾兰	虎尾兰	云南民族药物志：第三卷	To clear heat and resolve toxin, quicken blood and disperse swelling./Common cold, lung heat cough, toxin swelling of sores, knocks and falls, poisonous snake bite, scalds.	白族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000019	RAB5A	RAB5	RAB5A, member RAS oncogene family
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000241	CASP8	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5	caspase 8
TCMBANKGE000269	ATG5	APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5	autophagy related 5
TCMBANKGE000313	JUN	AP-1; AP1; c-Jun; cJUN; p39	Jun proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000523	BMP4	BMP2B; BMP2B1; MCOPS6; OFC11; ZYME	bone morphogenetic protein 4
TCMBANKGE000884	FN1	CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF	fibronectin 1
TCMBANKGE000898	MYC	MRTL; MYCC; bHLHe39; c-Myc	MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000962	TFEB	ALPHATFEB; BHLHE35; TCFEB	transcription factor EB
TCMBANKGE001006	BAK1	BAK; BAK-LIKE; BCL2L7; CDN1	BCL2 antagonist/killer 1
TCMBANKGE001098	NFKBIA	EDAID2; IKBA; MAD-3; NFKBI	NFKB inhibitor alpha
TCMBANKGE001106	MTOR	FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS	mechanistic target of rapamycin kinase
TCMBANKGE001113	ACTA2	ACTSA	actin alpha 2, smooth muscle
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001155	CASP7	CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3	caspase 7
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001170	CDK4	CMM3; PSK-J3	cyclin dependent kinase 4
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001181	TGFB1	CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta	transforming growth factor beta 1
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001197	FOS	AP-1; C-FOS; p55	Fos proto-oncogene, AP-1 transcription factor subunit