Compound Summary

  Compound Information

TCMBANKIN060290

药名:	Galgravin;di-o-methyltetrahydrofuriguaiacin b;(?)-galbelgin;saucernetin;(±)-galgravin;Veraguensin;(+)-galbelgin
分子式:	C22H28O5
Smiles:	CC1C(C(OC1C2=CC(=C(C=C2)OC)OC)C3=CC(=C(C=C3)OC)OC)C
成分:	HBIN027024;HBIN024107;HBIN027018;HBIN043224;HBIN027025;HBIN047799;HBIN027019
OB_score:	57.118922;25.53054;
CAS_id:	528-63-2;19950-55-1
SymMap_id:	SMIT02937;SMIT15178;SMIT15440;SMIT17606;SMIT15441;SMIT02956;SMIT18157
TCMID_id:	6409;8087;19389;8092;22367;8088
TCMSP_id:	MOL000313;MOL000333
PubChem_id:	101749;443018;44340797;15559448

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003919	Medicago sativa	苜蓿			To clear heat and cool blood, disinhibit damp and abate jaundice./Febrile diseases with vexation and fullness, jaundice, enteritis, dysentery, edema, urethral stone, hematochezia from hemorrhoids.
TCMBANKHE005688	Rhizoma Acori Talarinowii	石菖蒲			To eliminate damp and phlegm, to improve appetite, and to restore consciousness and benefit the mentality./Febrile diseases clouded spirit, phlegm reversal, amnesia, tinnitus, deafness, distending pain in stomach duct and abdomen, food-denying dysentery, wind-damp impediment pain, knocks and falls, scab and lichen with welling abscess and flat abscess.
TCMBANKHE004037	Rhizoma seu Herba Saururi	三白草			To remove toxic heat, and cause diuresis./Edema, beriberi, jaundice, strangury-turbidity, vaginal discharge, swollen welling abscess, clove sore.
TCMBANKHE004702	Magnolia acuminata	渐尖木兰; 尖头木兰
TCMBANKHE004773	Herba Pteridis multifidae	凤尾草			1. To clear heat and toxic material. 2. To cool the blood and stop bleeding./Dysentery, diarrhea, strangury-turbidity, vaginal discharge, jaundice, swelling toxin of clove sore, throat impediment with nipple moth, scrofula, parotitis, mastitis, ardent fever and convulsion, snake or insect bites, blood ejection, spontaneous external bleeding, hematuria, hematochezia, bleeding due to external injury.
TCMBANKHE005168		辛夷			Wind-cold common cold, headache, nasal congestion and runny nose, nasitis, nasosinusitis.
TCMBANKHE005412	Magnolia denudata [Syn. Magnolia heptapata]	玉兰			See Magnolia liliflora./See Magnolia liliflora.
TCMBANKHE005733	Saururus cernuus	梅州三白草
TCMBANKHE006932	Caulis Piperis Kadsurae;Caulis Piperis futokadsurae	海风藤			To relieve rheumatic conditions./Wind-cold-damp impediment, aching sinews in limb joints, hypertonicity of sinews and vessels.
TCMBANKHE006566	Cortex Moutan	牡丹皮			To remove heat from blood, to activate blood circulation and eliminate blood stasis./Appendicitis, dysentery, hypertension, allergic rhinitis, warm heat disease with fever, macular eruption, blood ejection, spontaneous external bleeding, steaming bone tidal fever due to yin vacuity, amenorrhea due to blood stasis, dysmenorrhea, concretion and conglomeration, swelling toxin of welling abscess and sore, painful wound from knocks and falls, wind-damp-heat impediment.
TCMBANKHE008660	Machilus thunbergii	红南皮;红楠皮			To warm center and normalize qi, soothe channels and quicken blood, disperse swelling and relieve pain./Sprain and contusion, incessant vomiting and diarrhea, cramp and swelling of feet.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000425	DRD1	DADR; DRD1A	dopamine receptor D1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000869	DRD2	D2DR; D2R	dopamine receptor D2
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005535	CHRM1	HM1; M1; M1R	cholinergic receptor muscarinic 1
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006943	CHRM3	EGBRS; HM3; PBS	cholinergic receptor muscarinic 3
TCMBANKGE008056	ADRA2C	ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR	adrenoceptor alpha 2C
TCMBANKGE008921	RXRA	NR2B1	retinoid X receptor alpha
TCMBANKGE009455	CHRM5	HM5	cholinergic receptor muscarinic 5
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE011923	CHRM4	HM4; M4R	cholinergic receptor muscarinic 4
TCMBANKGE012155	SLC6A3	DAT; DAT1; PKDYS; PKDYS1	solute carrier family 6 member 3
TCMBANKGE013926	RXRB	DAUDI6; H-2RIIBP; NR2B2; RCoR-1	retinoid X receptor beta
TCMBANKGE014625	OPRD1	DOP; DOR; DOR1; OPRD	opioid receptor delta 1
TCMBANKGE014975	PTAFR	PAFR	platelet activating factor receptor