Compound Summary


  Compound Information

药名:

smilagenin

分子式:

C27H44O3

Smiles:

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1

成分:

HBIN044212; HBIN025421; HBIN027995; HBIN043196; HBIN036749; HBIN044613; HBIN025419; HBIN043203; HBIN043195; HBIN043197

OB_score:

13.16164; 14.086399; 16.05314; 80.984145; 16.884959; 16.467209; 17.408045

CAS_id:

77-60-1; 470-01-9; 75172-34-8; 126-19-2

SymMap_id:

SMIT01619; SMIT05898; SMIT08643; SMIT00205; SMIT00356; SMIT00284; SMIT08811; SMIT00193; SMIT05897

TCMID_id:

20009; 7021; 21367; 8587; 15454; 7012; 24872; 19375

TCMSP_id:

MOL003894; MOL007158; MOL004495; MOL008581; MOL008522; MOL008519; MOL007362; MOL003893; MOL003892

PubChem_id:

91439; 99512; 99516; 53486207; 12304433; 156577; 12304430; 92095


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000698 Radix Asparagi 天冬 To replenish yin, promote fluid secretion and moisten the lung./1. Asparamide is an expectorant, antitussive and antiasthmatic.2. Inhibiting the cell growth of acute lymphocytic, acute monocytic and chronic granulocytic leukemias in vitro.
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001367 Semen Hyoscyami 天仙子 To relieve spasm and pain, and to cause tranquilization./1. Antisudorific, saliva antisecretory and mydriatic.2. Relaxing the smooth muscles.3. Increasing heart rate and exciting the respiratory center.
TCMBANKHE001571 Caulis Clematidis Armandii 川木通 To remove heat and induce diuresis, to stimulate menstrual discharge, and promote lactation./Treatment of edema, stranguria oliguria, arthralgia, amenorrhea, lack of lactation.
TCMBANKHE002083 石见穿
TCMBANKHE002445 Smilax aristolochiaefolia
TCMBANKHE003600 Gummi Elasticum 天然橡胶
TCMBANKHE003739 龙葵 Clove sore, swollen welling abscess, erysipelas, sprain from knocks and falls, mastitis, cervicitis, chronic bronchitis, chronic trachitis, acute nephritis, dysentery, infection of skin, leukorrhea, scant urine in children.
TCMBANKHE003752 Radix Salviae liguliobae 丹参 To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE005462 Bulbus Allii Macrostemi 薤白 To remove the retained phlegm from the chest, promote the flow of qi and relieve its stagnation./Chest impediment, phlegm-rheum cough asthma, diarrhea and tenesmus.
TCMBANKHE003957 Smilax sieboldii 鲶鱼须 To dispel wind and disinhibit damp, quicken blood and free network vessels, resolve toxin and dissipate binds./Wind-damp impediment pain, sore and boil, toxin swelling, scrofula.
TCMBANKHE004098 Herba Swertiae 青叶胆 To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis.
TCMBANKHE004260 Radix Ginseng 人参 To reinforce the vital energy, to remedy collapse and restore the normal pulse, to benefit the spleen and lung, to promote the production of body fluid, and to calm the nerves./Qi vacuity and verging on desertion, cold limbs and faint pulse, reduced food intake due to spleen vacuity, cough and asthma due to lung vacuity, fluid damage and thirst, diabetes mellitus due to internal heat, enduring illness qi vacuity, fright palpitation and insomnia, impotence, uterus cold, cardiac failure.
TCMBANKHE004287 Radix Achyranthis bidentatae 牛膝 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat.
TCMBANKHE004439 Rhizoma Smilacis Glabrae 土茯苓 To remove damp, to counteract toxicity, and to improve the mobility of joints./Damp-heat with strangury turbidity, vaginal discharge, swollen welling abscess, scrofula, scab and lichen, syphilis, mercurial poisoning.
TCMBANKHE007051 Stephania japonica 千金藤 To clear heat and resolve toxin, dispel wind and relieve pain, disinhibit water and disperse edema./Swelling pain in throat, swollen welling abscess, sore and boil, poisonous snake bite, wind-damp impediment pain, stomachache, beriberi with edema, nephritis with edema, urinary tract infection, rheumatic arthritis, sciatica.
TCMBANKHE006589 Agave americana var. marginata [Syn. Agave americana var. variegata] 无刺番麻 To moisten lung, transform phlegm, suppress cough./Vacuity taxation cough, blood ejection, asthma.
TCMBANKHE004858 白毛藤 Malaria, jaundice, edema, strangury, pain in joints due to rheumatalgia, erysipelas, clove sore.
TCMBANKHE004936 Cordyline strcta 剑叶铁树叶 To dissipate stasis and disperse swelling, cool blood and stanch bleeding./Knocks and falls, bleeding due to external injury, hematochezia, hematuria, nosebleed(epistaxis), cough with blood ejection, asthma, child gan accumulation, dysenter y.
TCMBANKHE004964 Agave east - one 剑麻
TCMBANKHE007143 Agave americana 番麻 To resolve toxin and draw out pus, kill worms, stanch bleeding./Sores with welling abscess and flat abscess, scab and lichen, pelvic inflammation, flooding.
TCMBANKHE007593 Physalis alkekengi var. franchetii 挂金灯 To clear heat and resolve toxin, disinhibit urine./Heat cough, throat pain, jaundice, dysentery, edema, clove sore, erysipelas.
TCMBANKHE008629 pollen typhae 蒲黄 To arrest bleeding, to remove blood stasis, and to relieve dysuria./Hyperlipemia, angina pectoris, exudative eczema, bleeding, hemoptysis, spontaneous external bleeding, blood ejection, hematochezia, hematuria, flooding and spotting, bleeding due to external injury, pain in heart and abdomen, dysmenorrhea, postpartum bleeding, postpartum abdominal pain, blood strangury with inhibited pain.
TCMBANKHE006128 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE006212 Semen Astragali Complanati;Semen Astragali Complati 潼蒺藜;沙苑子 Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
TCMBANKHE009129 Flos Trollii chinensis 金莲花 For clearing heat and removing toxic substances/Common cold with fever, swelling pain in throat, mouth sore, gum swelling and pain, gum hemorrhage, red eyes with gall, swelling toxin of clove sore, acute periostitis, acute lymphangitis.
TCMBANKHE007038 Solanum dulcamara 千年不烂心 To expel wind and eliminate damp, clear heat and resolve toxin./Wind-damp pain, tetanus, swollen welling abscess, malign sore, scab sore, bleeding due to external injury.
TCMBANKHE008778 Agave angustifolia 短叶龙舌兰
TCMBANKHE006597 Agave cantala 狭叶龙舌兰
TCMBANKHE009100 Alstonia yunnanensis 滇鸡骨常山 To interrupt malaria, clear heat and resolve toxin, stanch bleeding and disperse swelling./Malaria, common cold with fever, lung heat cough, swelling pain in throat, mouth and tongue sores, swelling toxin of welling abscess and sore, knocks and falls, bleeding due to external injury.
TCMBANKHE006736 Radix Smilacis 铁丝威灵仙
TCMBANKHE007508 Polianthes tuberosa 晚香玉 To clear heat and resolve toxin./Swelling toxin of welling abscess and sore.
TCMBANKHE009154 Radix Gentiae macrophyllae 秦艽 To relieve rheumatic conditions, and to remove damp-heat./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever.
TCMBANKHE007734 Fructus Tribuli 蒺藜 To subdue hyperactivity of the liver, to promote blood circulation, to dispel wind, to clear the eye of opacity, and to arrest itching./1. Antitussive, expectorant and antiasthmatic. 2. Its alcoholic infusion exerts hypotensive effect in anesthetized animals.
TCMBANKHE008256 Agave east - one 东一号剑麻
TCMBANKHE008687 Rhizoma Anemarrhee 知母 To remove heat and quench fire, and to promote the production of body fluid and relieve dryness syndromes./Diabetes mellitus, warm heat disease, ardent fever with vexation and thirst, cough and asthma, dry cough, constipation, steaming bone tidal fever, vacuity vexation and insomnia, strangury-turbidity.
TCMBANKHE000065/YEM-1032 Smilax scobinicaulis C.H.Wright 金刚刺|知梗菝葜 铁丝灵仙 云南民族药物志:第五卷 傈僳族
TCMBANKHE008911/YEM-126 Radix Achyranthis bidentatae|Achyranthes bidentata Blume 牛膝;怀牛膝|牛膝 牛膝 云南民族药物志:第一卷 To replenish the liver and the kidney, to strengthen the tendons and bones, to eliminate blood stasis and stimulate menstrual discharge, and to lead the blood to flow downward.Treament of soreness of the lumbar and knee joints with weakness inthe legs, amenorrhea with mass formation in the abdomen, dizziness due to hyperactivity of the liver./Aching in lumbus and knees, amenorrhea due to blood stasis, dysmenorrhea, postpartum blood stasis abdominal pain, concretion and conglomeration, retention of placenta , heat strangury, blood strangury, knocks and falls, swollen welling abscess and malign sore, swelling pain in throat. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/彝族
TCMBANKHE005594/YEM-148 Acorus calamus|Acorus calamus L. 白鲳;白菖|菖蒲 水菖蒲 云南民族药物志:第一卷 To transform phlegm and open orifices, dispel damp and fortify stomach, kill worms and relieve itch./Stupor due to phlegm reversal, wind stroke, epilepsy, fright palpitation and amnesia, tinnitus and deafness, food accumulation abdominal pain, diarrhea and dysentery, wind-damp pain, eczema, scab sore. 阿昌族/布朗族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/怒族/普米族/佤族/彝族/藏族
TCMBANKHE008257/YEM-229 Agave sisalana|Agave sisalana Perr ex Engelm. 剑麻 剑麻 云南民族药物志:第二卷 傣族/哈尼族/佤族
TCMBANKHE004965/YEM-229 Agave sisalana|Agave sisalana Perr ex Engelm. 剑麻;琼麻|剑麻 剑麻 云南民族药物志:第二卷 To cool blood and stanch bleeding, resolve toxin and disperse swelling./Tuberculosis and hemoptysis, spontaneous external bleeding, hematochezia, dysentery, welling abscess, hemorrhoids. 傣族/哈尼族/佤族
TCMBANKHE005619/YEM-411 Solanum melongena|Solanum melongena L. 茄子|茄 茄子 云南民族药物志:第二卷 To clear heat and quicken blood, disperse swelling and relieve pain./Intestinal wind bleeding, heat toxin swollen welling abscess. 傣族/德昂族/基诺族/佤族
TCMBANKHE003914/YEM-562 Dioscorea collettii|Dioscorea collettii Hook.f. 叉蕊薯蓣 叉蕊薯蓣 云南民族药物志:第三卷 To dispel wind and disinhibit damp, free network vessels and relieve pain, clear heat and resolve toxin./Wind-damp impediment pain, hypertonicity and numbness, qi stagnation stomachache, damp-heat jaundice, white turbidity, strangury with pain, leukorrhea, knocks and falls, damp sore with swelling toxin, wind papules, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE006634/YNS-20/YEM-636 Costus speciosus|Costus speciosus (Koen.) Smith|Costus speciosus(Koen.)Smith 樟柳头|闭鞘姜 闭鞘姜 云南药材标准:第五册|云南民族药物志:第四卷 除风解毒,利咽化痰,活血止痛,利水消肿,用于咽喉肿痛,咳喘痰多,痄腮,耳道溢脓,风湿痹痛,水肿,小便热涩疼痛,胆汁病(黄疸病,白疸病,黑疸病)|To move water and disperse swelling./Ascites, white turbidity, swollen welling abscess, malign sore. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/佤族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000737 PGR NR3C3; PR progesterone receptor
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor