Compound Summary

  Compound Information

TCMBANKIN060545

药名:	Uosolic Acid
分子式:	C30H48O3
Smiles:	CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O
成分:	HBIN047555; HBIN047612; HBIN008269; HBIN008614; HBIN008504
OB_score:	11.941806; 17.517414
CAS_id:	77-52-1; 989-30-0
SymMap_id:	SMIT09988; SMIT09988
TCMID_id:	34926; 33475; 36843
TCMSP_id:	MOL008760; MOL012360
PubChem_id:	64945; 139292119; 7163177

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001729	Cacumen Tamaricis	西河柳			To induce diaphoresis and dispel wind and to promote eruption./1. Bacteriostatic.2. Antipyretic.
TCMBANKHE004113	Fraxinus ornus	花白蜡树
TCMBANKHE004123	Medicinal Indianmulberry	巴戟天			Neurasthenia, impotence and emission, cold pain in abdomen, urinary incontinence, vacuity cold of uterus, wind-cold-damp impediment, aching in lumbus and knees.
TCMBANKHE004636	Fructus Zizyphi Jujubae	大枣			To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE004946	Herba Hedyotis Diffusae	白花蛇舌草			1. To eliminate heat and toxic material, promote blood circulation and remove blood stasis. 2. To clear dampness-heat./Lung heat cough asthma, swelling pain in throat, intestinal welling abscess, swelling of sores and boils, poisonous snake bite, heat strangury with inhibited pain, edema, dysentery, enteritis, damp-heat jaundice, carcinoma.
TCMBANKHE007950	Herba Lycopi;Eupatorium compositifolium	泽兰			1. To invigorate blood and remove stagnation; 2. To promote urination and reduce edema/Amenorrhea, concretion and conglomeration, postpartum blood stasis abdominal pain, edema in body and face, knocks and falls, incised wound.
TCMBANKHE008341	Fructus Zizyphi Jujubae	大枣			To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation.
TCMBANKHE005760	Craibiodendron yunnanese	金椰子			To dispel wind and quicken blood, free network vessels and relieve pain./Impediment pain, hemiplegia, knocks and falls.
TCMBANKHE009016	Herba Lycopi	泽兰叶;泽兰			Treatment of menstrual disorders, amenorrhea, dysmenorrhea, postpatum abdominal pain due to blood stasis, edema.1. To invigorate blood and remove stagnation; 2. To promote urination and reduce edema/Treatment of menstrual disorders, amenorrhea, dysmenorrhea, postpatum abdominal pain due to blood stasis, edema.Amenorrhea, concretion and conglomeration, postpartum blood stasis abdominal pain, edema in body and face, knocks and falls, incised wound.
TCMBANKHE005628/YEM-121	Fructus Chaenomelis|Chaenomeles speciosa (Sweet) Nakai	木瓜|皱皮木瓜	木瓜	云南民族药物志：第一卷	To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema.	傣族/景颇族/苗族/彝族/藏族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000130	TOP2A	TOP2; TP2A	DNA topoisomerase II alpha
TCMBANKGE000140	EIF4EBP1	4E-BP1; 4EBP1; BP-1; PHAS-I	eukaryotic translation initiation factor 4E binding protein 1
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000241	CASP8	ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5	caspase 8
TCMBANKGE000294	CDKN1A	CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1	cyclin dependent kinase inhibitor 1A
TCMBANKGE000396	TOP1	TOPI	DNA topoisomerase I
TCMBANKGE000513	CYP2C19	CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19	cytochrome P450 family 2 subfamily C member 19
TCMBANKGE000757	PTPN2	PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP	protein tyrosine phosphatase non-receptor type 2
TCMBANKGE000825	CDKN1B	CDKN4; KIP1; MEN1B; MEN4; P27KIP1	cyclin dependent kinase inhibitor 1B
TCMBANKGE000863	GPBAR1	BG37; GPCR19; GPR131; M-BAR; TGR5	G protein-coupled bile acid receptor 1
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000948	ERN1	IRE1; IRE1P; IRE1a; hIRE1p	endoplasmic reticulum to nucleus signaling 1
TCMBANKGE001006	BAK1	BAK; BAK-LIKE; BCL2L7; CDN1	BCL2 antagonist/killer 1
TCMBANKGE001037	MMP2	CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1	matrix metallopeptidase 2
TCMBANKGE001042	PTPN1	PTP1B	protein tyrosine phosphatase non-receptor type 1
TCMBANKGE001044	RPS6KB1	PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha	ribosomal protein S6 kinase B1
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001077	HSPA5	BIP; GRP78; HEL-S-89n; MIF2	heat shock protein family A (Hsp70) member 5
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001170	CDK4	CMM3; PSK-J3	cyclin dependent kinase 4
TCMBANKGE001181	TGFB1	CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta	transforming growth factor beta 1
TCMBANKGE001205	DDIT3	AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153	DNA damage inducible transcript 3
TCMBANKGE001991	CCND3	-	cyclin D3
TCMBANKGE002555	HSD11B1	11-DH; 11-beta-HSD1; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1	hydroxysteroid 11-beta dehydrogenase 1
TCMBANKGE005960	RORC	IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR	RAR related orphan receptor C
TCMBANKGE009472	AKR1B10	AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI	aldo-keto reductase family 1 member B10
TCMBANKGE010916	CCNE1	CCNE; pCCNE1	cyclin E1